Prognostic value of estrogen receptor and progesterone receptor tumor expression in Danish ovarian cancer patients: From the 'MALOVA' Ovarian Cancer Study

Oncology Reports

Volumn 18, Issue 5, 2007, Pages 1051-1059

  Høgdall, Estrid V S ^a   Christensen, Lise ^b   Høgdall, Claus K ^b   Blaakaer, Jan ^c   Gayther, Simon ^d   Jacobs, Ian J ^d   Christensen, Ib Jarle ^b   Kjaer, Susanne K ^a  

^a INSTITUTE OF CANCER EPIDEMIOLOGY   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Estrogen; Immunohistochemistry; Ovarian cancer; Progesterone; Prognosis; Tissue array

Indexed keywords

ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; TUMOR MARKER;

ARTICLE; CANCER STAGING; COLLOID CARCINOMA; CYSTADENOCARCINOMA; DENMARK; ENDOMETRIUM TUMOR; ENZYME IMMUNOASSAY; FEMALE; HUMAN; LUNG CARCINOMA; METABOLISM; OVARY TUMOR; PATHOLOGY; PROGNOSIS; SURVIVAL RATE;

ADENOCARCINOMA, MUCINOUS; CARCINOMA, LOBULAR; CYSTADENOCARCINOMA, SEROUS; DENMARK; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; NEOPLASM STAGING; OVARIAN NEOPLASMS; PROGNOSIS; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 38449084929     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Kjaerbye-Thygesen A, Huusom LD, Frederiksen K and Kjaer SK: Trends in the incidence and mortality of ovarian cancer in Denmark 1978-2002 - Comparison with other Nordic countries. Acta Obstet Gynecol Scand 84: 1006-1012, 2005. (Pubitemid 41400305)
2. Lu KH, Patterson AP, Wang L, et al: Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis. Clin Cancer Res 10: 3291-3300, 2004. (Pubitemid 38685433)
3. Rapkiewicz AV, Espina V, Petricoin EF and Liotta LA: Biomarkers of ovarian tumours. Eur J Cancer 40: 2604-2612, 2004. (Pubitemid 39487082)
4. Lindgren PR, Cajander S, Bäckström T, Gustafsson JA, Mäkelä S and Olofsson JI: Estrogen and progesterone receptors in ovarian epithelial tumors. Mol Cell Endocrinol 221: 97-104, 2004. (Pubitemid 38829727)
5. Lee P, Rosen DG, Zhu C, Silva EG and Liu J: Expression of progesterone receptor is a favorable prognostic marker in ovarian cancer. Gynecol Oncol 96: 671-677, 2005. (Pubitemid 40255486)
6. Syed V, Zhang X, Lau KM, Cheng R, Mukherjee K and Ho SM: Profiling estrogen-regulated gene expression changes in normal and malignant human ovarian surface epithelial cells. Oncogene 24: 8128-8143, 2005. (Pubitemid 41759812)
7. Bardin A, Hoffmann P, Boulle N, Katsaros D, Vignon F, Pujol P and Lazennec G: Involvement of estrogen receptor beta in ovarian carcinogenesis. Cancer Res 64: 5861-5869, 2004. (Pubitemid 39095587)
8. Lazennec G: Estrogen receptor beta, a possible tumor suppressor involved in ovarian carcinogenesis. Cancer Lett 231: 151-157, 2006.
9. Münstedt K, Steen J, Knauf AG, Buch T, von Georgi R and Franke FE: Steroid hormone receptors and long term survival in invasive ovarian cancer. Cancer 89: 1783-1791, 2000.
10. Kleine W, Maier T, Geyer H and Pfleiderer A: Estrogen and progesterone receptors in endometrial cancer and their prognostic relevance. Gynecol Oncol 38: 59-65, 1990. (Pubitemid 20206227)
11. Iwai K, Fukuda K, Hachisuga T, Mori M, Uchiyama M, Iwasaka T and Sugimori H: Prognostic significance of progesterone receptor immunohistochemistry for lymph node metastases in endometrial carcinoma. Gynecol Oncol 72: 351-359, 1999. (Pubitemid 29118193)
12. Kumar B, De Silva M, Venter DJ and Armes JE: Tissue microarrays: a practical guide. Pathology 36: 295-300, 2004. (Pubitemid 39178967)
13. Nocito A, Kononen J, Kallioniemi OP and Sauter G: Tissue microarrays (TMAs) for high-throughput molecular pathology research. Int J Cancer 94: 1-5, 2001. (Pubitemid 32801745)
14. Høgdall EV, Christensen L, Kjaer SK, et al: Distribution of HER-2 overexpression in ovarian carcinoma tissue and its prognostic value in patients with ovarian carcinoma: from the Danish MALOVA Ovarian Cancer Study. Cancer 98: 66-73, 2003. (Pubitemid 36741127)
15. Høgdall EV, Ryan A, Kjaer SK, et al: Loss of heterozygosity on the X chromosome is an independent prognostic factor in ovarian carcinoma: from the Danish 'MALOVA' Ovarian Carcinoma Study. Cancer 9: 2387-2395, 2003.
16. Kjaerbye-Thygesen A, Frederiksen K, Høgdall EV, et al: Smoking and overweight: negative prognostic factors in stage III epithelial ovarian cancer. Cancer Epidemiol Biomarkers Prev 15: 798-803, 2006.
17. Cox DR: Regression models and life tables. J Roy Stat Soc B 34: 187-220, 1972.
18. Remmele W and Stegner HE: Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue. Pathologe 8: 138-140, 1987.
19. van Doorn HC, Burger CW, van der Valk P and Bonfrèr HM: Oestrogen, progesterone, and androgen receptors in ovarian neoplasia: correlation between immunohistochemical and biochemical receptor analyses. J Clin Pathol 53: 201-205, 2000. (Pubitemid 30163603)
20. Lindgren P, Bäckström T, Mählck CG, Ridderheim M and Cajander S: Steroid receptors and hormones in relation to cell proliferation and apoptosis in poorly differentiated epithelial ovarian tumors. Int J Oncol 19: 31-38, 2001.