-
1
-
-
0142009533
-
Development of autoantibodies before the clinical onset of systemic lupus erythematosus
-
Arbuckle MR, McClain MT, Rubertone MV et al 2003 Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 349:1526-1533
-
(2003)
N Engl J Med
, vol.349
, pp. 1526-1533
-
-
Arbuckle, M.R.1
McClain, M.T.2
Rubertone, M.V.3
-
2
-
-
0035167967
-
-
Bennett CL, Christie J, Ramsdell F et al 2001 The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 27:20-21
-
Bennett CL, Christie J, Ramsdell F et al 2001 The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 27:20-21
-
-
-
-
3
-
-
0033555859
-
Emergent properties of networks of biological signaling pathways
-
Bhalla US, Iyengar R 1999 Emergent properties of networks of biological signaling pathways. Science 283:381-387
-
(1999)
Science
, vol.283
, pp. 381-387
-
-
Bhalla, U.S.1
Iyengar, R.2
-
4
-
-
12144291502
-
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
-
Bottini N, Musumeci L, Alonso A et al 2004 A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 36:337-338
-
(2004)
Nat Genet
, vol.36
, pp. 337-338
-
-
Bottini, N.1
Musumeci, L.2
Alonso, A.3
-
5
-
-
19344369383
-
Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice
-
Bygrave AE, Rose KL, Cortes-Hernandez J et al 2004 Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice. PLoS Biol 2:E243
-
(2004)
PLoS Biol
, vol.2
-
-
Bygrave, A.E.1
Rose, K.L.2
Cortes-Hernandez, J.3
-
6
-
-
5644236524
-
Systemic lupus erythematosus genome scan: Support for linkage at 1q23, 2q33, 16q12-13, and 17q21-23 and novel evidence at 3p24, 10q23-24, 13q32, and 18q22-23
-
Cantor RM, Yuan J, Napier S et al 2004 Systemic lupus erythematosus genome scan: support for linkage at 1q23, 2q33, 16q12-13, and 17q21-23 and novel evidence at 3p24, 10q23-24, 13q32, and 18q22-23. Arthritis Rheum 50:3203-3210
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3203-3210
-
-
Cantor, R.M.1
Yuan, J.2
Napier, S.3
-
7
-
-
0029866102
-
Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: Implications for coagulation events and antigenic spread in systemic lupus erythematosus
-
Casciola-Rosen L, Rosen A, Petri M, Schlissel M 1996 Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus. Proc Natl Acad Sci USA 93:1624-1629
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1624-1629
-
-
Casciola-Rosen, L.1
Rosen, A.2
Petri, M.3
Schlissel, M.4
-
8
-
-
0034121119
-
PARP alleles and SLE: Failure to confirm association with disease susceptibility
-
Criswell LA, Moser KL, Gaffney PM et al 2000 PARP alleles and SLE: failure to confirm association with disease susceptibility. J Clin Invest 105:1501-1502
-
(2000)
J Clin Invest
, vol.105
, pp. 1501-1502
-
-
Criswell, L.A.1
Moser, K.L.2
Gaffney, P.M.3
-
9
-
-
1342298274
-
Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus
-
Croker BP, Gilkeson G, Morel L 2003 Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus. Genes Immun 4:575-585
-
(2003)
Genes Immun
, vol.4
, pp. 575-585
-
-
Croker, B.P.1
Gilkeson, G.2
Morel, L.3
-
10
-
-
0026537198
-
A revised estimate of twin concordance in systemic lupus erythematosus
-
Deapen D, Escalante A, Weinrib L et al 1992 A revised estimate of twin concordance in systemic lupus erythematosus. Arthritis Rheum 35:311-318
-
(1992)
Arthritis Rheum
, vol.35
, pp. 311-318
-
-
Deapen, D.1
Escalante, A.2
Weinrib, L.3
-
11
-
-
0015310384
-
The sampling theory of selectively neutral alleles
-
Ewens WJ 1972 The sampling theory of selectively neutral alleles. Theor Popul Biol 3:87-112
-
(1972)
Theor Popul Biol
, vol.3
, pp. 87-112
-
-
Ewens, W.J.1
-
12
-
-
0035960122
-
Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
-
Fajans SS, Bell GI, Polonsky KS 2001 Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 345:971-980
-
(2001)
N Engl J Med
, vol.345
, pp. 971-980
-
-
Fajans, S.S.1
Bell, G.I.2
Polonsky, K.S.3
-
13
-
-
1542376173
-
The transfer of a laboratory based hypothesis to a clinically useful therapy: The development of anti-TNF therapy of rheumatoid arthritis
-
Feldmann M, Brennan FM, Williams RO, Woody JN, Maini RN 2004 The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis. Best Pract Res Clin Rheumatol 18:59-80
-
(2004)
Best Pract Res Clin Rheumatol
, vol.18
, pp. 59-80
-
-
Feldmann, M.1
Brennan, F.M.2
Williams, R.O.3
Woody, J.N.4
Maini, R.N.5
-
14
-
-
0036546060
-
An osteopontin (SPP1) polymorphism is associated with systemic lupus erythematosus
-
Forton AC, Petri MA, Goldman D, Sullivan KE 2002 An osteopontin (SPP1) polymorphism is associated with systemic lupus erythematosus. Hum Mutat 19:459
-
(2002)
Hum Mutat
, vol.19
, pp. 459
-
-
Forton, A.C.1
Petri, M.A.2
Goldman, D.3
Sullivan, K.E.4
-
15
-
-
4243900858
-
A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families
-
Gaffney PM, Kearns GM, Shark KB et al 1998 A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. Proc Natl Acad Sci USA 95: 14875-14879
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14875-14879
-
-
Gaffney, P.M.1
Kearns, G.M.2
Shark, K.B.3
-
16
-
-
0033929750
-
Genome screening in human systemic lupus erythematosus: Results from a second Minnesota cohort and combined analyses of 187 sibpair families
-
Gaffney PM, Ortmann WA, Selby SA et al 2000 Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sibpair families. Am J Hum Genet 66:547-556
-
(2000)
Am J Hum Genet
, vol.66
, pp. 547-556
-
-
Gaffney, P.M.1
Ortmann, W.A.2
Selby, S.A.3
-
17
-
-
18544367934
-
Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus
-
Graham RR, Ortmann WA, Langefeld CD et al 2002 Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. Am J Hum Genet 71:543-553
-
(2002)
Am J Hum Genet
, vol.71
, pp. 543-553
-
-
Graham, R.R.1
Ortmann, W.A.2
Langefeld, C.D.3
-
18
-
-
4644328058
-
Dissection of BXSB lupus phenotype using mice congenic for chromosome 1 demonstrates that separate intervals direct different aspects of disease
-
Haywood ME, Rogers NJ, Rose SJ et al 2004 Dissection of BXSB lupus phenotype using mice congenic for chromosome 1 demonstrates that separate intervals direct different aspects of disease. J Immunol 173:4277-4285
-
(2004)
J Immunol
, vol.173
, pp. 4277-4285
-
-
Haywood, M.E.1
Rogers, N.J.2
Rose, S.J.3
-
19
-
-
0031229830
-
Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus
-
Hochberg MC 1997 Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 40:1725
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1725
-
-
Hochberg, M.C.1
-
20
-
-
0032727902
-
Association of Fas/APO-1 gene polymorphism with systemic lupus erythematosus in Japanese
-
Horiuchi T, Nishizaka H, Yasunaga S et al 1999 Association of Fas/APO-1 gene polymorphism with systemic lupus erythematosus in Japanese. Rheumatology (Oxford) 38:516-520
-
(1999)
Rheumatology (Oxford)
, vol.38
, pp. 516-520
-
-
Horiuchi, T.1
Nishizaka, H.2
Yasunaga, S.3
-
22
-
-
0032765523
-
A comparison of genome-scans performed in multicase families with systemic lupus erythematosus from different population groups
-
Johanneson B, Steinsson K, Lindqvist AK et al 1999 A comparison of genome-scans performed in multicase families with systemic lupus erythematosus from different population groups. J Autoimmun 13:137-141
-
(1999)
J Autoimmun
, vol.13
, pp. 137-141
-
-
Johanneson, B.1
Steinsson, K.2
Lindqvist, A.K.3
-
23
-
-
22144479219
-
Analysis of HLA DR, HLA DQ, C4A, FcgammaRIIa, FcgammaRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcgammaRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility
-
Jonsen A, Bengtsson AA, Sturfelt G, Truedsson L 2004 Analysis of HLA DR, HLA DQ, C4A, FcgammaRIIa, FcgammaRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcgammaRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility. Arthritis Res Ther 6:R557-562
-
(2004)
Arthritis Res Ther
, vol.6
-
-
Jonsen, A.1
Bengtsson, A.A.2
Sturfelt, G.3
Truedsson, L.4
-
24
-
-
7044260956
-
New insights into disease pathogenesis from mouse lupus genetics
-
Jorgensen TN, Gubbels MR, Kotzin BL 2004 New insights into disease pathogenesis from mouse lupus genetics. Curr Opin Immunol 16:787-793
-
(2004)
Curr Opin Immunol
, vol.16
, pp. 787-793
-
-
Jorgensen, T.N.1
Gubbels, M.R.2
Kotzin, B.L.3
-
25
-
-
0037379229
-
The Fc gamma RIIIA-F158 allele is a risk factor for the development of lupus nephritis: A meta-analysis
-
Karassa FB, Trikalinos TA, Ioannidis JP 2003 The Fc gamma RIIIA-F158 allele is a risk factor for the development of lupus nephritis: a meta-analysis. Kidney Int 63:1475-1482
-
(2003)
Kidney Int
, vol.63
, pp. 1475-1482
-
-
Karassa, F.B.1
Trikalinos, T.A.2
Ioannidis, J.P.3
-
26
-
-
20944434679
-
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities
-
Kochi Y, Yamada R, Suzuki A et al 2005 A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet 37:478-485
-
(2005)
Nat Genet
, vol.37
, pp. 478-485
-
-
Kochi, Y.1
Yamada, R.2
Suzuki, A.3
-
27
-
-
26444593959
-
FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling
-
Kono H, Kyogoku C, Suzuki T et al 2005 FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling. Hum Mol Genet 14:2881-2892
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2881-2892
-
-
Kono, H.1
Kyogoku, C.2
Suzuki, T.3
-
28
-
-
0035983742
-
Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: Contribution of FCGR2B to genetic susceptibility
-
Kyogoku C, Dijstelbloem HM, Tsuchiya N et al 2002 Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility. Arthritis Rheum 46:1242-1254
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1242-1254
-
-
Kyogoku, C.1
Dijstelbloem, H.M.2
Tsuchiya, N.3
-
29
-
-
0037994582
-
Studies on the association of Fc gamma receptor IIA, IIB, IIIA and IIIB polymorphisms with rheumatoid arthritis in the Japanese: Evidence for a genetic interaction between HLA-DRB1 and FCGR3A
-
Kyogoku C, Tsuchiya N, Matsuta K, Tokunaga K 2002 Studies on the association of Fc gamma receptor IIA, IIB, IIIA and IIIB polymorphisms with rheumatoid arthritis in the Japanese: evidence for a genetic interaction between HLA-DRB1 and FCGR3A. Genes Immun 3: 488-493
-
(2002)
Genes Immun
, vol.3
, pp. 488-493
-
-
Kyogoku, C.1
Tsuchiya, N.2
Matsuta, K.3
Tokunaga, K.4
-
30
-
-
0028578184
-
Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Drosophila melanogaster
-
Lai C, Lyman RF, Long AD, Langley CH, Mackay TF 1994 Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Drosophila melanogaster. Science 266:1697-1702
-
(1994)
Science
, vol.266
, pp. 1697-1702
-
-
Lai, C.1
Lyman, R.F.2
Long, A.D.3
Langley, C.H.4
Mackay, T.F.5
-
31
-
-
18344390831
-
Fcgamma receptor IIIA polymorphism in Korean patients with systemic lupus erythematosus
-
Lee EB, Lee YJ, Baek HJ et al 2002 Fcgamma receptor IIIA polymorphism in Korean patients with systemic lupus erythematosus. Rheumatol Int 21:222-226
-
(2002)
Rheumatol Int
, vol.21
, pp. 222-226
-
-
Lee, E.B.1
Lee, Y.J.2
Baek, H.J.3
-
32
-
-
29144433522
-
The mannose-binding lectin gene polymorphisms and systemic lupus erythematosus: Two case-control studies and a meta-analysis
-
Lee YH, Witte T, Momot T et al 2005 The mannose-binding lectin gene polymorphisms and systemic lupus erythematosus: two case-control studies and a meta-analysis. Arthritis Rheum 52:3966-3974
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3966-3974
-
-
Lee, Y.H.1
Witte, T.2
Momot, T.3
-
33
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN 2003 Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33:177-182
-
(2003)
Nat Genet
, vol.33
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.3
Lander, E.S.4
Hirschhorn, J.N.5
-
34
-
-
3242773701
-
Both risk alleles for FcgammaRIIA and FcgammaRIIIA are susceptibility factors for SLE: A unifying hypothesis
-
Magnusson V, Johanneson B, Lima G, Odeberg J, Alarcon-Segovia D, Alarcon-Riquelme ME 2004 Both risk alleles for FcgammaRIIA and FcgammaRIIIA are susceptibility factors for SLE: a unifying hypothesis. Genes Immun 5:130-137
-
(2004)
Genes Immun
, vol.5
, pp. 130-137
-
-
Magnusson, V.1
Johanneson, B.2
Lima, G.3
Odeberg, J.4
Alarcon-Segovia, D.5
Alarcon-Riquelme, M.E.6
-
35
-
-
2542505506
-
The role of complement in the development of systemic lupus erythematosus
-
Manderson AP, Botto M, Walport MJ 2004 The role of complement in the development of systemic lupus erythematosus. Annu Rev Immunol 22:431-456
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 431-456
-
-
Manderson, A.P.1
Botto, M.2
Walport, M.J.3
-
36
-
-
0036707519
-
Fcgamma receptor IIa, IIIa, and IIIb polymorphisms in German patients with systemic lupus erythematosus: Association with clinical symptoms
-
Manger K, Repp R, Jansen M et al 2002 Fcgamma receptor IIa, IIIa, and IIIb polymorphisms in German patients with systemic lupus erythematosus: association with clinical symptoms. Ann Rheum Dis 61:786-792
-
(2002)
Ann Rheum Dis
, vol.61
, pp. 786-792
-
-
Manger, K.1
Repp, R.2
Jansen, M.3
-
37
-
-
0022235453
-
Genetic deficiency of C4, C2 or C1q and lupus syndromes. Association with anti-Ro (SS-A) antibodies
-
Meyer O, Hauptmann G, Tappeiner G, Ochs HD, Mascart-Lemone F 1985 Genetic deficiency of C4, C2 or C1q and lupus syndromes. Association with anti-Ro (SS-A) antibodies. Clin Exp Immunol 62:678-684
-
(1985)
Clin Exp Immunol
, vol.62
, pp. 678-684
-
-
Meyer, O.1
Hauptmann, G.2
Tappeiner, G.3
Ochs, H.D.4
Mascart-Lemone, F.5
-
38
-
-
0034612320
-
Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains
-
Morel L, Croker BP, Blenman KR et al 2000 Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains. Proc Natl Acad Sci USA 97:6670-6675
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6670-6675
-
-
Morel, L.1
Croker, B.P.2
Blenman, K.R.3
-
39
-
-
4243900937
-
Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees
-
Moser KL, Neas BR, Salmon JE et al 1998 Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees. Proc Natl Acad Sci USA 95:14869-14874
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14869-14874
-
-
Moser, K.L.1
Neas, B.R.2
Salmon, J.E.3
-
40
-
-
0027514171
-
Molecular mimicry and the generation of host defense protein diversity
-
Murphy PM 1993 Molecular mimicry and the generation of host defense protein diversity. Cell 72:823-826
-
(1993)
Cell
, vol.72
, pp. 823-826
-
-
Murphy, P.M.1
-
42
-
-
34547481484
-
Genome scan stratified by the presence of antidouble-stranded DNA (dsDNA) autoantibody in pedigrees multiplex for systemic lupus erythematosus (SLE) establishes linkages at 19p13.2 (SLED1) and 18q21.1 (SLED2)
-
Namjou B, Nath SK, Kilpatrick J et al 2002 Genome scan stratified by the presence of antidouble-stranded DNA (dsDNA) autoantibody in pedigrees multiplex for systemic lupus erythematosus (SLE) establishes linkages at 19p13.2 (SLED1) and 18q21.1 (SLED2). Genes Immun 3 Suppl 1, S35-41
-
(2002)
Genes Immun
, vol.3
, Issue.SUPPL. 1
-
-
Namjou, B.1
Nath, S.K.2
Kilpatrick, J.3
-
43
-
-
0036845210
-
Stratification of pedigrees multiplex for systemic lupus erythematosus and for self-reported rheumatoid arthritis detects a systemic lupus erythematosus susceptibility gene (SLER1) at 5p15.3
-
Namjou B, Nath SK, Kilpatrick J et al 2002 Stratification of pedigrees multiplex for systemic lupus erythematosus and for self-reported rheumatoid arthritis detects a systemic lupus erythematosus susceptibility gene (SLER1) at 5p15.3. Arthritis Rheum 46:2937-2945
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2937-2945
-
-
Namjou, B.1
Nath, S.K.2
Kilpatrick, J.3
-
44
-
-
0035208598
-
Evidence for a susceptibility gene, SLEV1, on chromosome 17p13 in families with vitiligo-related systemic lupus erythematosus
-
Nath SK, Kelly JA, Namjou B et al 2001 Evidence for a susceptibility gene, SLEV1, on chromosome 17p13 in families with vitiligo-related systemic lupus erythematosus. Am J Hum Genet 69:1401-1406
-
(2001)
Am J Hum Genet
, vol.69
, pp. 1401-1406
-
-
Nath, S.K.1
Kelly, J.A.2
Namjou, B.3
-
45
-
-
0036664610
-
SLEB3 in systemic lupus erythematosus (SLE) is strongly related to SLE families ascertained through neuropsychiatric manifestations
-
Nath SK, Kelly JA, Reid J et al 2002 SLEB3 in systemic lupus erythematosus (SLE) is strongly related to SLE families ascertained through neuropsychiatric manifestations. Hum Genet 111:54-58
-
(2002)
Hum Genet
, vol.111
, pp. 54-58
-
-
Nath, S.K.1
Kelly, J.A.2
Reid, J.3
-
46
-
-
19944433325
-
Association of a functional singlenucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus
-
Orozco G, Sanchez E, Gonzalez-Gay MA et al 2005 Association of a functional singlenucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Rheum 52:219-224
-
(2005)
Arthritis Rheum
, vol.52
, pp. 219-224
-
-
Orozco, G.1
Sanchez, E.2
Gonzalez-Gay, M.A.3
-
47
-
-
0036340979
-
The population genetics of adaptation: The adaptation of DNA sequences
-
Orr HA 2002 The population genetics of adaptation: the adaptation of DNA sequences. Evolution Int J Org Evolution 56:1317-1330
-
(2002)
Evolution Int J Org Evolution
, vol.56
, pp. 1317-1330
-
-
Orr, H.A.1
-
48
-
-
0037264546
-
The autoantibody repertoire: Searching for order
-
Plotz PH 2003 The autoantibody repertoire: searching for order. Nat Rev Immunol 3: 73-78
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 73-78
-
-
Plotz, P.H.1
-
49
-
-
0034969437
-
Are rare variants responsible for susceptibility to complex diseases?
-
Pritchard JK 2001 Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet 69:124-137
-
(2001)
Am J Hum Genet
, vol.69
, pp. 124-137
-
-
Pritchard, J.K.1
-
50
-
-
0036799545
-
The allelic architecture of human disease genes: Common disease-common variant . . . or not?
-
Pritchard JK, Cox NJ 2002 The allelic architecture of human disease genes: common disease-common variant . . . or not? Hum Mol Genet 11:2417-2423
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2417-2423
-
-
Pritchard, J.K.1
Cox, N.J.2
-
51
-
-
13244277850
-
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
-
Prokunina L, Castillejo-Lopez C, Oberg F et al 2002 A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet 32:666-669
-
(2002)
Nat Genet
, vol.32
, pp. 666-669
-
-
Prokunina, L.1
Castillejo-Lopez, C.2
Oberg, F.3
-
52
-
-
34547414073
-
The genetics of systemic lupus erythematosus stratified by renal disease: Linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3)
-
Quintero-Del-Rio AI, Kelly JA, Kilpatrick J, James JA, Harley JB 2002 The genetics of systemic lupus erythematosus stratified by renal disease: linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3). Genes Immun 3 Suppl 1, S57-62
-
(2002)
Genes Immun
, vol.3
, Issue.SUPPL. 1
-
-
Quintero-Del-Rio, A.I.1
Kelly, J.A.2
Kilpatrick, J.3
James, J.A.4
Harley, J.B.5
-
53
-
-
28544444365
-
The R620W C/T polymorphism of the gene PTPN22 is associated with SLE independently of the association of PDCD1
-
Reddy MV, Johansson M, Sturfelt G et al 2005 The R620W C/T polymorphism of the gene PTPN22 is associated with SLE independently of the association of PDCD1. Genes Immun 6:658-662
-
(2005)
Genes Immun
, vol.6
, pp. 658-662
-
-
Reddy, M.V.1
Johansson, M.2
Sturfelt, G.3
-
54
-
-
0035451780
-
On the allelic spectrum of human disease
-
Reich DE, Lander ES 2001 On the allelic spectrum of human disease. Trends Genet 17:502-510
-
(2001)
Trends Genet
, vol.17
, pp. 502-510
-
-
Reich, D.E.1
Lander, E.S.2
-
55
-
-
0023135007
-
Assessing the role of HLA-linked and unlinked determinants of disease
-
Risch N 1987 Assessing the role of HLA-linked and unlinked determinants of disease. Am J Hum Genet 40:1-14
-
(1987)
Am J Hum Genet
, vol.40
, pp. 1-14
-
-
Risch, N.1
-
56
-
-
55949129208
-
-
Rus VHA, Hochberg MC eds, Oxford University Press
-
Rus VHA, Hochberg MC (eds) 2001 Systemic lupus erythematosus. Oxford University Press, 123-140
-
(2001)
Systemic lupus erythematosus
, pp. 123-140
-
-
-
57
-
-
0347917232
-
Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus
-
Russell AI, Cunninghame Graham DS, Shepherd C et al 2004 Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus. Hum Mol Genet 13:137-147
-
(2004)
Hum Mol Genet
, vol.13
, pp. 137-147
-
-
Russell, A.I.1
Cunninghame Graham, D.S.2
Shepherd, C.3
-
58
-
-
0012156457
-
Specificlocus test shows ethylnitrosourea to be the most potent mutagen in the mouse
-
Russell WL, Kelly EM, Hunsicker PR, Bangham JW, Maddux SC, Phipps EL 1979 Specificlocus test shows ethylnitrosourea to be the most potent mutagen in the mouse. Proc Natl Acad Sci USA 76:5818-5819
-
(1979)
Proc Natl Acad Sci USA
, vol.76
, pp. 5818-5819
-
-
Russell, W.L.1
Kelly, E.M.2
Hunsicker, P.R.3
Bangham, J.W.4
Maddux, S.C.5
Phipps, E.L.6
-
59
-
-
0019974408
-
Associations between systemic lupus erythematosus and the major histocompatibility complex: Clinical and immunological considerations
-
Schur PH, Meyer I, Garovoy M, Carpenter CB 1982 Associations between systemic lupus erythematosus and the major histocompatibility complex: clinical and immunological considerations. Clin Immunol Immunopathol 24:263-275
-
(1982)
Clin Immunol Immunopathol
, vol.24
, pp. 263-275
-
-
Schur, P.H.1
Meyer, I.2
Garovoy, M.3
Carpenter, C.B.4
-
60
-
-
0033029712
-
Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families
-
Shai R, Quismorio FP Jr, Li L et al 1999 Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families. Hum Mol Genet 8:639-644
-
(1999)
Hum Mol Genet
, vol.8
, pp. 639-644
-
-
Shai, R.1
Quismorio Jr, F.P.2
Li, L.3
-
61
-
-
0030060230
-
Evolution of hemopoietic ligands and their receptors. Influence of positive selection on correlated replacements throughout ligand and receptor proteins
-
Shields DC, Harmon DL, Whitehead AS 1996 Evolution of hemopoietic ligands and their receptors. Influence of positive selection on correlated replacements throughout ligand and receptor proteins. J Immunol 156:1062-1070
-
(1996)
J Immunol
, vol.156
, pp. 1062-1070
-
-
Shields, D.C.1
Harmon, D.L.2
Whitehead, A.S.3
-
62
-
-
13844292408
-
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
-
Sigurdsson S, Nordmark G, Goring HH et al 2005 Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet 76:528-537
-
(2005)
Am J Hum Genet
, vol.76
, pp. 528-537
-
-
Sigurdsson, S.1
Nordmark, G.2
Goring, H.H.3
-
63
-
-
0036798007
-
The allelic structure of common disease
-
Smith DJ, Lusis AJ 2002 The allelic structure of common disease. Hum Mol Genet 11: 2455-2461
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2455-2461
-
-
Smith, D.J.1
Lusis, A.J.2
-
65
-
-
0344405696
-
Analysis of polymorphisms affecting immune complex handling in systemic lupus erythematosus
-
Sullivan KE, Jawad AF, Piliero LM et al 2003 Analysis of polymorphisms affecting immune complex handling in systemic lupus erythematosus. Rheumatology (Oxford) 42:446-452
-
(2003)
Rheumatology (Oxford)
, vol.42
, pp. 446-452
-
-
Sullivan, K.E.1
Jawad, A.F.2
Piliero, L.M.3
-
66
-
-
0030447092
-
Mannose-binding protein genetic polymorphisms in black patients with systemic lupus erythematosus
-
Sullivan KE, Wooten C, Goldman D, Petri M 1996 Mannose-binding protein genetic polymorphisms in black patients with systemic lupus erythematosus. Arthritis Rheum 39:2046-2051
-
(1996)
Arthritis Rheum
, vol.39
, pp. 2046-2051
-
-
Sullivan, K.E.1
Wooten, C.2
Goldman, D.3
Petri, M.4
-
67
-
-
0020436689
-
The 1982 revised criteria for the classification of systemic lupus erythematosus
-
Tan EM, Cohen AS, Fries JF et al 1982 The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25:1271-1277
-
(1982)
Arthritis Rheum
, vol.25
, pp. 1271-1277
-
-
Tan, E.M.1
Cohen, A.S.2
Fries, J.F.3
-
68
-
-
7444227970
-
Coding single-nucleotide polymorphisms associated with complex vs. Mendelian disease: Evolutionary evidence for differences in molecular effects
-
Thomas PD, Kejariwal A 2004 Coding single-nucleotide polymorphisms associated with complex vs. Mendelian disease: evolutionary evidence for differences in molecular effects. Proc Natl Acad Sci USA 101:15398-15403
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15398-15403
-
-
Thomas, P.D.1
Kejariwal, A.2
-
69
-
-
4344633188
-
Update on human systemic lupus erythematosus genetics
-
Tsao BP 2004 Update on human systemic lupus erythematosus genetics. Curr Opin Rheumatol 16:513-521
-
(2004)
Curr Opin Rheumatol
, vol.16
, pp. 513-521
-
-
Tsao, B.P.1
-
70
-
-
0033560931
-
PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus
-
Tsao BP, Cantor RM, Grossman JM et al 1999 PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus. J Clin Invest 103:1135-1140
-
(1999)
J Clin Invest
, vol.103
, pp. 1135-1140
-
-
Tsao, B.P.1
Cantor, R.M.2
Grossman, J.M.3
-
71
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda H, Howson JM, Esposito L et al 2003 Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423:506-511
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.2
Esposito, L.3
-
72
-
-
21144438325
-
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
-
Vinuesa CG, Cook MC, Angelucci C et al 2005 A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature 435:452-458
-
(2005)
Nature
, vol.435
, pp. 452-458
-
-
Vinuesa, C.G.1
Cook, M.C.2
Angelucci, C.3
-
73
-
-
2942620983
-
Illuminating autoimmune regulators through controlled variation of the mouse genome sequence
-
Vinuesa CG, Goodnow CC 2004 Illuminating autoimmune regulators through controlled variation of the mouse genome sequence. Immunity 20:669-679
-
(2004)
Immunity
, vol.20
, pp. 669-679
-
-
Vinuesa, C.G.1
Goodnow, C.C.2
-
74
-
-
0035555022
-
The genetics of complex autoimmune diseases: Non-MHC susceptibility genes
-
Wandstrat A, Wakeland E 2001 The genetics of complex autoimmune diseases: non-MHC susceptibility genes. Nat Immunol 2:802-809
-
(2001)
Nat Immunol
, vol.2
, pp. 802-809
-
-
Wandstrat, A.1
Wakeland, E.2
-
75
-
-
13144265739
-
Genome-wide association studies: Theoretical and practical concerns
-
Wang WY, Barratt BJ, Clayton DG, Todd JA 2005 Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet 6 109-118
-
(2005)
Nat Rev Genet
, vol.6
, pp. 109-118
-
-
Wang, W.Y.1
Barratt, B.J.2
Clayton, D.G.3
Todd, J.A.4
-
76
-
-
7944220775
-
The allelic spectra of common diseases may resemble the allelic spectrum of the full genome
-
Wang WY, Pike N 2004 The allelic spectra of common diseases may resemble the allelic spectrum of the full genome. Med Hypotheses 63:748-751
-
(2004)
Med Hypotheses
, vol.63
, pp. 748-751
-
-
Wang, W.Y.1
Pike, N.2
-
77
-
-
0029058932
-
Genes and arthritis
-
Wordsworth P 1995 Genes and arthritis. Br Med Bull 51:249-266
-
(1995)
Br Med Bull
, vol.51
, pp. 249-266
-
-
Wordsworth, P.1
-
78
-
-
23644432242
-
Association analysis of the R620W polymorphism of protein tyrosine phosphatase PTPN22 in systemic lupus erythematosus families: Increased T allele frequency in systemic lupus erythematosus patients with autoimmune thyroid disease
-
Wu H, Cantor RM, Graham DS et al 2005 Association analysis of the R620W polymorphism of protein tyrosine phosphatase PTPN22 in systemic lupus erythematosus families: increased T allele frequency in systemic lupus erythematosus patients with autoimmune thyroid disease. Arthritis Rheum 52:2396-2402
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2396-2402
-
-
Wu, H.1
Cantor, R.M.2
Graham, D.S.3
-
79
-
-
0029737324
-
Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease
-
Wu J, Wilson J, He J, Xiang L, Schur PH, Mountz JD 1996 Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. J Clin Invest 98:1107-1113
-
(1996)
J Clin Invest
, vol.98
, pp. 1107-1113
-
-
Wu, J.1
Wilson, J.2
He, J.3
Xiang, L.4
Schur, P.H.5
Mountz, J.D.6
-
80
-
-
17044421246
-
Recent findings on genes associated with inflammatory disease
-
Yamada R, Ymamoto K 2005 Recent findings on genes associated with inflammatory disease. Mutat Res 573:136-151
-
(2005)
Mutat Res
, vol.573
, pp. 136-151
-
-
Yamada, R.1
Ymamoto, K.2
-
81
-
-
10544249874
-
Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
-
Yamagata K, Oda N, Kaisaki PJ et al 1996 Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3). Nature 384:455-458
-
(1996)
Nature
, vol.384
, pp. 455-458
-
-
Yamagata, K.1
Oda, N.2
Kaisaki, P.J.3
-
82
-
-
0035089823
-
Low-binding alleles of Fcgamma receptor types IIA and IIIA are inherited independently and are associated with systemic lupus erythematosus in Hispanic patients
-
Zuniga R, Ng S, Peterson MG et al 2001 Low-binding alleles of Fcgamma receptor types IIA and IIIA are inherited independently and are associated with systemic lupus erythematosus in Hispanic patients. Arthritis Rheum 44:361-367
-
(2001)
Arthritis Rheum
, vol.44
, pp. 361-367
-
-
Zuniga, R.1
Ng, S.2
Peterson, M.G.3
|