Pre-emptive analgesia using intravenous fentanyl plus low-dose ketamine for radical prostatectomy under general anesthesia does not produce short-term or long-term reductions in pain or analgesic use

Pain

Volumn 110, Issue 3, 2004, Pages 707-718

  Katz, Joel ^a,b,c,f   Schmid, Roger ^b   Snijdelaar, Dirk G ^d   Coderre, Terence J ^e   McCartney, Colin J L ^b,c   Wowk, Adarose ^b  

^a YORK UNIVERSITY   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^f TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Analgesia; Fentanyl; Ketamine

Indexed keywords

FENTANYL; KETAMINE; MORPHINE;

ADULT; AGED; AGITATION; ANALGESIA; ANAPHYLAXIS; ARTICLE; BLEEDING; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELIRIUM TREMENS; DISABILITY; DOUBLE BLIND PROCEDURE; DROWSINESS; DRUG EFFICACY; DRUG USE; FOLLOW UP; GENERAL ANESTHESIA; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH; PAIN ASSESSMENT; PAIN THRESHOLD; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; PROSTATECTOMY; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; VIVID DREAM;

AGED; ANALGESIA; ANALYSIS OF VARIANCE; ANESTHESIA, GENERAL; CHI-SQUARE DISTRIBUTION; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FENTANYL; HUMANS; INFUSIONS, INTRAVENOUS; KETAMINE; MALE; MIDDLE AGED; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PROSTATECTOMY; TIME FACTORS;

EID: 3843149647     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2004.05.011     Document Type: Article

References (44)

1. Adam F., Libier M., Oszustowicz T., Lefebvre D., Beal J., Meynadier J. Preoperative small-dose ketamine has no preemptive analgesic effect in patients undergoing total mastectomy. Anesth Analg. 89:1999;444-447
2. Aida S., Yamakura T., Baba H., Taga K., Fukuda S., Shimoji K. Preemptive analgesia by intravenous low-dose ketamine and epidural morphine in gastrectomy: a randomized double-blind study. Anesthesiology. 92:2000;1624-1630
3. Brown B.W., Brauner C., Chan A., Gutierrez D., Herson J., Lovato J., Polsley J. STPLAN version 4.0: June, 1993. Calculations for sample sizes and related problems. 1993;The University of Texas M.D. Anderson Cancer Center, Houston, TX
4. Celerier E., Rivat C., Jun Y., Laulin J.P., Larcher A., Reynier P., Simonnet G. Long-lasting hyperalgesia induced by fentanyl in rats: preventive effect of ketamine. Anesthesiology. 92:2000;465-472
5. Chapman V., Dickenson A.H. The combination of NMDA antagonism and morphine produces profound antinociception in the rat dorsal horn. Brain Res. 573:1992;321-323
6. Clements J.A., Nimmo W.S., Grant I.S. Bioavailability, pharmacokinetics, and analgesic activity of ketamine in humans. J Pharm Sci. 71:1982;539-542
7. Crain S.M., Shen K.F. Antagonists of excitatory opioid receptor functions enhance morphine's analgesic potency and attenuate opioid tolerance/dependence liability. Pain. 84:2000;121-131
8. Dahl V., Ernoe P.E., Steen T., Raeder J.C., White P.F. Does ketamine have preemptive effects in women undergoing abdominal hysterectomy procedures? Anesth Analg. 90:2000;1419-1422
9. Dajczman E., Gordon A., Kriesman H., Wolklove N. Long-term postthoracotomy pain. Chest. 99:1991;270-274
10. Dallal GE. DESIGN: a supplementary module for SYSTAT and SYGRAPH, SYSTAT. Evanston, IL; 1988.
11. Dickenson A.H. NMDA receptor antagonists: interactions with opioids. Acta Anaesthesiol Scand. 41:1997;112-115
12. Fu E.S., Miguel R., Scharf J.E. Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery. Anesth Analg. 84:1997;1086-1090
13. Glantz S.A. Primer of biostatistics: the program. 1997;McGraw-Hill, New York
14. Hammersley J.M., Handscomb D.C. Monte Carlo methods. 1964;Methuen, London
15. Hirata S., Seo N., Murayama T., Fujiwara T., Sekiguchi M. Addition of low-dose ketamine to general anesthesia does not improve cardiovascular response during conventional abdominal surgery. Anesth Analg. 81:1995;1111-1112
16. Hoffmann V.L., Baker A.K., Vercauteren M.P., Adriaensen H.F., Meert T.F. Epidural ketamine potentiates epidural morphine but not fentanyl in acute nociception in rats. Eur J Pain. 7:2003;121-130
17. Katz J. Timing of treatment and pre-emptive analgesia. Rice A., Warfield C., Justins D., Eccleston C. Clinical pain management: acute volume. 2003;113-162 Arnold, London
18. Katz J., Melzack R. Measurement of pain. Surg Clin North Am. 79:1999;231-252
19. Katz J., Clairoux M., Kavanagh B.P., Roger S., Nierenberg H., Redahan C., Sandler A.N. Pre-emptive lumbar epidural anaesthesia reduces postoperative pain and patient-controlled morphine consumption after lower abdominal surgery. Pain. 59:1994;395-403
20. Katz J., Cohen L., Schmid R., Chan V.W., Wowk A. Postoperative morphine use and hyperalgesia are reduced by preoperative but not intraoperative epidural analgesia: implications for preemptive analgesia and the prevention of central sensitization. Anesthesiology. 98:2003;1449-1460
21. Kee W.D., Khaw K.S., Ma M.L., Mainland P.A., Gin T. Postoperative analgesic requirement after cesarean section: a comparison of anesthetic induction with ketamine or thiopental. Anesth Analg. 85:1997;1294-1298
22. Kissin I. Preemptive analgesia. Anesthesiology. 93:2000;1138-1143
23. Kissin I., Bright C.A., Bradley E.L. Jr. The effect of ketamine on opioid-induced acute tolerance: can it explain reduction of opioid consumption with ketamine-opioid analgesic combinations? Anesth Analg. 91:2000;1483-1488
24. Laulin J.P., Maurette P., Corcuff J.B., Rivat C., Chauvin M., Simonnet G. The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance. Anesth Analg. 94:2002;1263-1269
25. Mao J., Price D.D., Mayer D.J. Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions. Pain. 62:1995;259-274
26. Marietta M.P., Way W.L., Castagnoli N. Jr., Trevor A.J. On the pharmacology of the ketamine enantiomorphs in the rat. J Pharmacol Exp Ther. 202:1977;157-165
27. Mathisen L.C., Skjelbred P., Skoglund L.A., Oye I. Effect of ketamine, an NMDA receptor inhibitor, in acute and chronic orofacial pain. Pain. 61:1995;215-220
28. McCartney C.J.L., Sinha A., Katz J. A qualitative systematic review of the role of the N-methyl-D-aspartate (NMDA) receptor antagonists in preventive analgesia. Anesth Analg. 98:2004;1385-1400
29. Melzack R. The McGill Pain Questionnaire: major properties and scoring methods. Pain. 1:1975;277-299
30. Menigaux C., Fletcher D., Dupont X., Guignard B., Guirimand F., Chauvin M. The benefits of intraoperative small-dose ketamine on postoperative pain after anterior cruciate ligament repair. Anesth Analg. 90:2000;129-135
31. Roytblat L., Korotkoruchko A., Katz J., Glazer M., Greemberg L., Fisher A. Postoperative pain: the effect of low-dose ketamine in addition to general anesthesia. Anesth Analg. 77:1993;1161-1165
32. Schmid R.L., Sandler A.N., Katz J. Use and efficacy of low-dose ketamine in the management of acute postoperative pain: a review of current techniques and outcomes. Pain. 82:1999;111-125
33. Sethna N.F., Liu M., Gracely R., Bennett G.J., Max M.B. Analgesic and cognitive effects of intravenous ketamine-alfentanil combinations versus either drug alone after intradermal capsaicin in normal subjects. Anesth Analg. 86:1998;1250-1256
34. Snijdelaar D.G., Cornelisse H.B., Schmid R.L., Katz J. A randomised, controlled study of peri-operative low dose s(+)-ketamine in combination with postoperative patient-controlled s(+)-ketamine and morphine after radical prostatectomy. Anaesthesia. 59:2004;222-228
35. Spielberger C.D., Gorsuch R.L., Lushene R.E. STAI manual for the State-Trait Anxiety Inventory. 1970;Consulting Psychologists Press Inc., Palo Alto, CA
36. Tverskoy M., Oz Y., Isakson A., Finger J., Bradley E.L. Jr., Kissin I. Preemptive effect of fentanyl and ketamine on postoperative pain and wound hyperalgesia. Anesth Analg. 78:1994;205-209
37. Ware J.E.J., Johnston S.A., Davies-Avery A., Brook R.H. Conceptualization and measurement of health for adults in the Health Insurance Study. Vol. III. Mental health (R-1987/3-HEW). 1979;RAND Corporation, Santa Monica, CA
38. Weinstein M.C., Berwick D.M., Goldman P.A., Murphy J.M., Barsky A. A comparison of three psychiatric screening tests using receiver operating characteristics (ROC) analysis. Med Care. 27:1989;593-607
39. White P.F., Way W.L., Trevor A.J. Ketamine - its pharmacology and therapeutic uses. Anesthesiology. 56:1982;119-136
40. White P.F., Schuttler J., Shafer A., Stanski D.R., Horai Y., Trevor A.J. Comparative pharmacology of the ketamine isomers. Studies in volunteers. Br J Anaesth. 57:1985;197-203
41. Wilcox G.L. Excitatory neurotransmitters and pain. Bond M.R., Charlton J.E., Woolf C.J. Proceedings of the VI World Congress on Pain. 1991;97-117 Elsevier, Amsterdam
42. Wilder-Smith O.H., Arendt-Nielsen L., Gaumann D., Tassonyi E., Rifat K.R. Sensory changes and pain after abdominal hysterectomy: a comparison of anesthetic supplementation with fentanyl versus magnesium or ketamine. Anesth Analg. 86:1998;95-101
43. Woolf C.J., Chong M.S. Preemptive analgesia - treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg. 77:1993;362-379
44. Woolf C.J., Thompson S.W. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain. 44:1991;293-299