Modeling Interactions between Electrical Activity and Second-Messenger Cascades in Aplysia Neuron R15

Journal of Neurophysiology

Volumn 91, Issue 5, 2004, Pages 2297-2311

  Yu, Xintian ^a   Byrne, John H ^a   Baxter, Douglas A ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CALCIUM ION; CALMODULIN; CYCLIC AMP; PHOSPHODIESTERASE;

APLYSIA; ARTICLE; BIOMECHANICS; ELECTRIC ACTIVITY; MEMBRANE CONDUCTANCE; MODEL; NERVE CELL; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SECOND MESSENGER; SIMULATION;

ADENYLATE CYCLASE; ALGORITHMS; ANIMALS; APLYSIA; CALCIUM CHANNELS; CALCIUM SIGNALING; CALMODULIN; COMPUTER SIMULATION; CYCLIC AMP; ELECTROPHYSIOLOGY; MEMBRANE POTENTIALS; MODELS, NEUROLOGICAL; NEURONS; PHOSPHORIC DIESTER HYDROLASES; POTASSIUM CHANNELS; SECOND MESSENGER SYSTEMS;

EID: 3843145622     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00787.2003     Document Type: Article

References (64)

1. 2+/calmodulin and transmitter. J Neurosci 11: 2655-2665, 1991.
2. Adams DJ and Gage PW. Characteristics of sodium and calcium conductance changes produced by membrane depolarization in an Aplysia neurone. J Physiol 289: 143-161, 1979.
3. Adams SR, Bacskai BJ, Hochner B, Kaang BK, Kandel ER, Mahaut-Smith M, and Tsien RY. Confocal imaging of cAMP signals in Aplysia neurons. Jpn J Physiol 43, Suppl. 1: S91-S93, 1993.
4. Adams SR, Harootunian AT, Buechler YJ, Taylor SS, and Tsien RY. Fluorescence ratio imaging of cyclic AMP in single cells. Nature 349: 694-697, 1991.
5. Adams WB. Slow depolarizing and hyperpolarizing currents which mediate bursting in Aplysia neurone R15. J Physiol 360: 51-68, 1985.
6. Adams WB and Benson JA. The generation and modulation of endogenous rhythmicity in the Aplysia bursting pacemaker neurone R15. Prog Biophys Mol Biol 46: 1-49, 1985.
7. Adams WB and Levitan IB. Voltage and ion dependences of the slow currents which mediate bursting in Aplysia neurone R15. J Physiol 360: 69-93, 1985.
8. Alevizos A, Karagogeos D, Weiss KR, Buck L, and Koester J. R15 alpha 1 and R15 alpha 2 peptides from Aplysia: comparison of bioactivity, distribution, and function of two peptides generated by alternative splicing. J Neurobiol 22: 405-417, 1991.
9. Arvanitaki A and Charlazonitis N. Electrical properties and temporal organization in oscillatory neurons. In: Neurobiology of Invertebrates, edited by Salanki J. New York: Plenum, 1968, p. 169-199.
10. Baxter DA, Canavier CC, Lechner H, Butera RJ, DeFranceschi AA, Clark JW, and Byrne JH. Coexisting stable oscillatory states in single cell and multicellular neuronal oscillators. In: Oscillations in Neural Systems, edited by Levine D, Brown V, and Shirey T. Hillsdale, NJ: Erlbaum, 2000, p. 51-77.
11. Bertram R. Reduced-system analysis of the effects of serotonin on a molluscan burster neuron. Biol Cybern 70: 359-368, 1994.
12. Blumenthal DK and Stull JT. Activation of skeletal muscle myosin light chain kinase by calcium and calmodulin. Biochemistry 19: 5608-5614, 1980.
13. Brooker G. Oscillation of cyclic adenosine monophosphate concentration during the myocardial contraction cycle. Science 182: 933-934, 1973.
14. Butera RJ. Multirhythmic bursting. Chaos 8: 274-284, 1998.
15. Butera RJ Jr, Clark JW Jr, Canavier CC, Baxter DA, and Byrne JH. Analysis of the effects of modulatory agents on a modeled bursting neuron: dynamic interactions between voltage and calcium dependent systems. J Comput Neurosci 2: 19-44, 1995.
16. Calvin WH and Hartline DK. Retrograde invasion of lobster stretch receptor somata in control of firing rate and extra spike patterning. J Neurophysiol 40: 106-118, 1977.
17. Canavier CC, Baxter DA, Clark JW, and Byrne JH. Nonlinear dynamics in a model neuron provide a novel mechanism for transient synaptic inputs to produce long-term alterations of postsynaptic activity. J Neurophysiol 69: 2252-2257, 1993.
18. Canavier CC, Baxter DA, Clark JW, and Byrne JH. Multiple modes of activity in a model neuron suggest a novel mechanism for the effects of neuromodulators. J Neurophysiol 72: 872-882, 1994.
19. Canavier CC, Clark JW, and Byrne JH. Simulation of the bursting activity of neuron R15 in Aplysia: role of ionic currents, calcium balance, and modulatory transmitters. J Neurophysiol 66: 2107-2124, 1991.
20. Carpenter DO, McCreery MJ, Woodbury CM, and Yarowsky PJ. Modulation of endogenous discharge in neuron R15 through specific receptors for several neurotransmitters. In: Abnormal Neuronal Dischargers, edited by Chalazonitis N and Boisson M. New York: Raven Press, 1978, p. 189-203.
21. Chafouleas JG, Bolton WE, Hidaka H, Boyd AE 3rd, and Means AR. Calmodulin and the cell cycle: involvement in regulation of cell-cycle progression. Cell 28: 41-50, 1982.
22. Chay TR. Eyring rate theory in excitable-membranes-application to neuronal oscillations. J Phys Chem 87: 2935-2940, 1983.
23. Cooper DM, Mons N, and Karpen JW. Adenylyl cyclases and the interaction between calcium and cAMP signaling. Nature 374: 421-424, 1995.
24. Destexhe A, Babloyantz A, and Sejnowski TJ. Ionic mechanisms for intrinsic slow oscillations in thalamic relay neurons. Biophys J 65: 1538-1552, 1993.
25. Drummond AH, Benson JA, and Levitan IB. Serotonin-induced hyperpolarization of an indentified Aplysia neuron is mediated by cyclic AMP. Proc Natl Acad Sci USA 77: 5013-5017, 1980.
26. Egorov AV, Hamam BN, Fransen E, Hasselmo ME, and Alonso AA. Graded persistent activity in entorhinal cortex neurons. Nature 420: 173-178, 2002.
27. 2+/calmodulin sensitivity may be common to all forms of neural adenylate cyclase. Proc Natl Acad Sci USA 86: 9564-9568, 1989.
28. Ermentrout B. Simulating, Analyzing, and Animating Dynamical Systems. Philadelphia, PA: Society for Industrial and Applied Mathematics, 2002.
29. Gerisch G, Hulser D, Malchow D, and Wick U. Cell communication by periodic cyclic-AMP pulses. Philos Trans R Soc Lond B Biol Sci 272: 181-192, 1975.
30. Gerisch G and Wick U. Intracellular oscillations and release of cyclic AMP from Dictyostelium cells. Biochem Biophys Res Commun 65: 364-370, 1975.
31. 2+ spikes. Nature 418: 93-96, 2002.
32. Gorman AL, Hermann A, and Thomas MV. Intracellular calcium and the control of neuronal pacemaker activity. Fed Proc 40: 2233-2239, 1981.
33. Gorman AL, Hermann A, and Thomas MV. Ionic requirements for membrane oscillations and their dependence on the calcium concentration in a molluscan pace-maker neurone. J Physiol 327: 185-217, 1982.
34. Gorman AL and Thomas MV. Changes in the intracellular concentration of free calcium ions in a pace-maker neurone, measured with the metallochromic indicator dye arsenazo III. J Physiol 275: 357-376, 1978.
35. Gospe SM Jr and Wilson WA Jr. Dopamine inhibits burst-firing of neurosecretory cell R 15 in Aplysia californica: establishment of a dose-response relationship. J Pharmacol Exp Ther 214: 112-118, 1980.
36. Guckenheimer J and Holmes P. Nonlinear Oscillations, Dynamical Systems, and Bifurcation of Vector Fields. New York: Springer-Verlag, 1983.
37. Gunning R. Increased numbers of ion channels promoted by an intracellular second messenger. Science 235: 80-82, 1987.
38. Haisenleder DJ, Yasin M, and Marshall JC. Enhanced effectiveness of pulsatile 3′,5′-cyclic adenosine monophosphate in stimulating prolactin and alpha-subunit gene expression. Endocrinology 131: 3027-3033, 1992.
39. Heyward P, Ennis M, Keller A, and Shipley MT. Membrane bistability in olfactory bulb mitral cells. J Neurosci 21: 5311-5320, 2001.
40. 2+ binding sites of calmodulin. J Biol Chem 271: 761-767, 1996.
41. Kramer RH, Levitan ES, Wilson MP, and Levitan IB. Mechanism of calcium-dependent inactivation of a potassium current in Aplysia neuron R15: interaction between calcium and cyclic AMP. J Neurosci 8: 1804-1813, 1988.
42. Kramer RH and Levitan IB. Calcium-dependent inactivation of a potassium current in the Aplysia neuron R15. J Neurosci 8: 1796-1803, 1988.
43. Kramer RH and Levitan IB. Activity-dependent neuromodulation in Aplysia neuron R15: intracellular calcium antagonizes neurotransmitter responses mediated by cAMP. J Neurophysiol 63: 1075-1088, 1990.
44. Lechner HA, Baxter DA, Clark JW, and Byrne JH. Bistability and its regulation by serotonin in the endogenously bursting neuron R15 in Aplysia. J Neurophysiol 75: 957-962, 1996.
45. Lee RH and Heckman CJ. Bistability in spinal motoneurons in vivo: systematic variations in rhythmic firing patterns. J Neurophysiol 80: 572-582, 1998.
46. + currents. Proc Natl Acad Sci USA 84: 6307-6311, 1987.
47. Levitan ES and Levitan IB. Serotonin acting via cyclic AMP enhances both the hyperpolarizing and depolarizing phases of bursting pacemaker activity in the Aplysia neuron R15. J Neurosci 8: 1152-1161, 1988.
48. Lotshaw DP, Levitan ES, and Levitan IB. Fine tuning of neuronal electrical activity: modulation of several ion channels by intracellular messengers in a single identified nerve cell. J Exp Biol 124: 307-322, 1986.
49. Lotshaw DP and Levitan IB. Reciprocal modulation of calcium current by serotonin and dopamine in the identified Aplysia neuron R15. Brain Res 439: 64-76, 1988.
50. 2+-regulated dynamic compartmentalization of calmodulin in living smooth muscle cells. J Biol Chem 270:21532-21538, 1995.
51. Marder E, Abbott LF, Turrigiano GG, Liu Z, and Golowasch J. Memory from the dynamics of intrinsic membrane currents. Proc Natl Acad Sci USA 93: 13481-13486, 1996.
52. Mathieu PA and Roberge FA. Characteristics of pacemaker oscillations in Aplysia neurons. Can J Physiol Pharmacol 49: 787-795, 1971.
53. 2+-calmodulin in intact cells. J Biol Chem 274: 6827-6830, 1999.
54. Rasmussen H and Barrett PQ. Calcium messenger system: an integrated view. Physiol Rev 64: 938-984, 1984.
55. Reisert J and Matthews HR. Responses to prolonged odour stimulation in frog olfactory receptor cells. J Physiol 534: 179-191, 2001.
56. Rich TC, Fagan KA, Nakata H, Schaack J, Cooper DM, and Karpen JW. Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion. J Gen Physiol 116: 147-161, 2000.
57. Rich TC, Fagan KA, Tse TE, Schaack J, Cooper DM, and Karpen JW. A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell. Proc Natl Acad Sci USA 98: 13049-13054, 2001.
58. Rinzel J and Ermentrout GB. Analysis of neuronal excitability and oscillations. In: Methods in Neuronal Modeling: From Synapses to Networks, edited by Koch C and Segev I. Cambridge, MA: MIT Press, 1989, p. 135-169.
59. Rinzel J and Lee YS. Dissection of a model for neuronal parabolic bursting. J Math Biol 25: 653-675, 1987.
60. 2+ sensitivity of light chain phosphorylation within smooth muscle cells. J Biol Chem 269: 9912-9920, 1994.
61. Tomchik KJ and Devreotes PN. Adenosine 3′,5′-monophosphate waves in Dictyostelium discoideum: a demonstration by isotope dilution-fluorography. Science 212: 443-446, 1981.
62. Vitalis EA, Costantin JL, Tsai PS, Sakakibara H, Paruthiyil S, Iiri T, Martini JF, Taga M, Choi AL, Charles AC, and Weiner RI. Role of the cAMP signaling pathway in the regulation of gonadotropin-releasing hormone secretion in GT1 cells. Proc Natl Acad Sci USA 97: 1861-1866, 2000.
63. 2+/calmodulin sensitivity of adenylyl cyclase in Aplysia, Drosophila, and rat. J Neurochem 59: 1736-1744, 1992.
64. 2+ interplay: a matter of oscillation patterns. Trends Neurosci 26: 53-55, 2003.