Protective effects of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxy- phenylethylamino) propane hydrochloride (DDPH) on brain ischemia injury in rats

Yaoxue Xuebao

Volumn 38, Issue 10, 2003, Pages 725-727

  Qu, Ling ^a   Wang, Wei Ting ^a   Guo, Lian Jun ^a   Wang, Fang ^a   Lü, Qing ^a   Qian, Jia Qing ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

1 (2, 6 dimethylphenoxy) 2 (3, 4 dimethoxyphenylethylamino) propane hydrochloride; Cerebral ischemia; Reperfusion injury; Superoxide dismutase

Indexed keywords

1 (2,6 DIMETHYLPHENOXY) 2 (3,4 DIMETHOXYPHENYLETHYLAMINO)PROPANE; 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXYPHENYLETHYLAMINO)PROPANE; MALONALDEHYDE; NEUROPROTECTIVE AGENT; PHENETHYLAMINE DERIVATIVE; SUPEROXIDE DISMUTASE;

ANIMAL; ARTICLE; BRAIN; BRAIN ISCHEMIA; CEREBRAL ARTERY DISEASE; FEMALE; MALE; METABOLISM; PATHOLOGY; RAT; REPERFUSION INJURY; WISTAR RAT;

ANIMALS; BRAIN; BRAIN ISCHEMIA; FEMALE; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MALONDIALDEHYDE; NEUROPROTECTIVE AGENTS; PHENETHYLAMINES; RATS; RATS, WISTAR; REPERFUSION INJURY; SUPEROXIDE DISMUTASE;

EID: 3843144119     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Xia L, Ni PZ, Ji M. Synthesis of mexiletine analogues[J]. Acta Pham Sin, 1984, 19(9): 656-659.
2. Zheng H, Hu XD, Qian JQ. Comparison of the blocking effect 1-(2, 6-dimethylphenoxy)-2-(3, 4-dimethoxyphenyletylamino) propane hydrochloride (DDPH) and its (-) enantiomers on calcium channel and α1-adrenoreceptor[J] . Acta Univ Med Tongji, 2001, 30 (6): 522-524.
3. Wang WT, Guo LJ, Qu L, et al. 1-(2,6-dimethylphenoxy)-2-(3,4- dimethoxyphenyletylamino) propane hydrochloride on brain ischemia injury in rats[J]. Chin J Pharmacol Toxicol, 2001, 15(2): 137-140.
4. Cai J, Zhen XM, Guo LJ. A study on focal cerebral ischemia model with suture method [J]. Acta Univ Med Tongji, 1998, 27(2): 167-168.
5. Zhou YQ, Liu L. Evaluation of motor functional compensation after the focal cerebral ischemia in rats[J]. J Fourth Mil Med Univ , 2001, 22 (Suppl): 6-9.
6. Engelhard K, Werner C, Reeker W, et al. Desflurane and isoflurane improve neurological outcome after incomplete cerebral ischaemia in rats[J]. Br J Anaesth, 1999, 83(3): 415-421.
7. Liu X, Zhu XZ. The application of the cerebral ischemia model in medicine screen test[J]. Chin Pharmacol Bull, 1998, 14(5): 399-401.
8. Wang F, Qu L, Lu Q, et al. Effect of phenolic alkaoids from menispemum dauricum on myocardial-cerebral ischemia-reperfusion injury in rabbits[J] . Acta Pharmacol Sin, 2001, 22(12): 1130-1134.