Stereoselective synthesis and preliminary evaluation of new D-3-heteroarylcarbonylalanines as ligands of the NMDA receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 17, 2004, Pages 4399-4403

  Lima, Paulo G ^a,b   Caruso, Rodrigo R B ^c   Alves, Simone O ^c   Pessôa, Renata F ^c   Mendonç Silva, Dayde L ^c   Nunes, Ricardo J ^d   Noël, François ^c   Castro, Newton G ^c   Costa, Paulo R R ^a  

^a Nucleo de Pesq de Produtos Naturais   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c ICB   (Brazil)

^d FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

D Aminoacid; Glutamate; Glycine; NMDA

Indexed keywords

ALANINE DERIVATIVE; DIZOCILPINE; GLYCINE; MANNITOL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PYRIDINE DERIVATIVE; THIOPHENE DERIVATIVE;

ANIMAL CELL; ARTICLE; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; FETUS; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; RAT; STEREOCHEMISTRY;

ALANINE; ANIMALS; CEREBRAL CORTEX; DIZOCILPINE MALEATE; DRUG EVALUATION, PRECLINICAL; LIGANDS; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; STEREOISOMERISM; THIOPHENES;

EID: 3843141833     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.06.062     Document Type: Article

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