Synthesis and cellular uptake of a fluorescently labeled cyclic PNA-based compound

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 17, 2004, Pages 4435-4438

  Caldarelli, Sergio ^a   Depecker, Geoffrey ^a   Patino, Nadia ^a   Di Giorgio, Audrey ^a   Barouillet, Thibault ^b   Doglio, Alain ^b   Condom, Roger ^a  

^a UNIVERSITÉ CÔTE D'AZUR   (France)

^b INSERM   (France)

Author keywords

Cellular uptake; Cyclic PNA; Fluorescence microscopy

Indexed keywords

FLUORESCEIN; FLUORESCENT DYE; NUCLEIC ACID; POLYAMIDE;

ARTICLE; CELL LEVEL; DRUG SYNTHESIS; DRUG UPTAKE; ELECTROPORATION; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL;

CELL MEMBRANE; FLUORESCEIN; HELA CELLS; HUMANS; JURKAT CELLS; NUCLEIC ACID CONFORMATION; NYLONS; RNA;

EID: 3843118964     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.06.055     Document Type: Article

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12. max2 = 271.0 nm
13. Abbreviations: Alloc: allyloxycarbonyl; Boc: tertiobutyloxycarbonyl; DEA: diethylamine; DIPEA: diisopropylethylamine; DMF: dimethylformamide; FITC: fluorescein isothiocyanate; HATU: O-(7-aza-1-benzotriazolyl)-N,N,N′, N′-tetramethyluronium hexa-fluorophosphate; HOAt: 1-hydroxy-7- azabenzotriazole; Mmt: monomethoxytrityl; TFA: trifluoroacetic acid; TFMSA: trifluoromethane sulfonic acid; Troc: trichloroethyloxycarbonyl
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