Physiological and psychological correlates of fatigue in HIV disease

Biological Research for Nursing

Volumn 6, Issue 1, 2004, Pages 59-74

  Phillips, Kenneth D ^a   Sowell, Richard L ^b   Rojas, Michelle ^c   Tavakoli, Abbas ^a   Fulk, Laura J ^a   Hand, Gregory A ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b KENNESAW STATE UNIVERSITY   (United States)

^c Richland Primary Health Care Association   (United States)

Author keywords

Anxiety; Depression; Fatigue; HIV; Perceived stress; Sleep

Indexed keywords

ADULT; ANEMIA; ANXIETY; ARTICLE; BIOLOGICAL MODEL; BLOOD; CD4 LYMPHOCYTE COUNT; DEPRESSION; FATIGUE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INSOMNIA; MALE; MENTAL STRESS; MIDDLE AGED; PATHOPHYSIOLOGY; PREVALENCE; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL MODEL; QUALITY OF LIFE; QUESTIONNAIRE; REGRESSION ANALYSIS; RISK FACTOR; UNITED STATES; VIROLOGY; VIRUS LOAD;

ADULT; ANEMIA; ANXIETY; CD4 LYMPHOCYTE COUNT; DEPRESSION; FATIGUE; FEMALE; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; MODELS, PSYCHOLOGICAL; PREVALENCE; QUALITY OF LIFE; QUESTIONNAIRES; REGRESSION ANALYSIS; RISK FACTORS; SLEEP INITIATION AND MAINTENANCE DISORDERS; SOUTH CAROLINA; STRESS, PSYCHOLOGICAL; VIRAL LOAD;

EID: 3843107060     PISSN: 10998004     EISSN: 15524175     Source Type: Journal    
DOI: 10.1177/1099800404264846     Document Type: Article

References (93)

1. Adinolfi A. 2001a. Assessment and treatment of HIV-related fatigue. J Assoc Nurses AIDS Care 12 Suppl:29-34.
2. Adinolfi A. 2001b. The need for national guidelines to manage fatigue in HIV-positive patients. J Assoc Nurses AIDS Care 12 Suppl:39-42.
3. Anonymous. 2002. Lactic acidosis and anti-retroviral drugs. Prescrire Internationale 11:113-5.
4. Atanackovic D, Brunner-Weinzierl MC, Kroger H, Serke S, Deter HC. 2002. Acute psychological stress simultaneously alters hormone levels, recruitment of lymphocyte subsets, and production of reactive oxygen species. Immunol Invest 31:73-91.
5. Barroso J. 1999. A review of fatigue in people with HIV infection. J Assoc Nurses AIDS Care 10:42-9.
6. Barroso J, Carlson JR, Meynell J. 2003. Physiological and psychological markers associated with HIV-related fatigue. Clin Nurs Res 12;49-68.
7. Barroso J, Lynn MR. 2002. Psychometric properties of the HIV-Related Fatigue Scale. J Assoc Nurses AIDS Care 13:66-75.
8. Barroso J, Preisser JS, Leserman J, Gaynes BN, Golden RN, Evans DN. 2002. Predicting fatigue and depression in HIV-positive gay men. Psychosomatics 43:317-25.
9. Beekman AT, Deeg DJ, Van Limbeek J, Braam AW, De Vries MZ, Van Tilburg W. 1997. Criterion validity of the Center for Epidemiologic Studies Depression scale (CES-D): results from a community-based sample of older subjects in the Netherlands. Psychol Med 27:231-5.
10. Bormann J, Shively M, Smith TL, Gifford AL. 2001. Measurement of fatigue in HIV-positive adults: reliability and validity of the Global Fatigue Index. J Assoc Nurses AIDS Care 12:75-83.
11. Born J, Kern W, Bieber K, Fehm-Wolfsdorf G, Schiebe M, Fehm HL. 1986. Night-time plasma cortisol secretion is associated with specific sleep stages. Biol Psychiatry 21:1415-24.
12. Breitbart W, McDonald MV, Rosenfeld B, Monkman ND, Passik S. 1998. Fatigue in ambulatory AIDS patients. J Pain Symptom Manage 15:159-67.
13. Bruera E, Brenneis C, Michaud M, Rafter J, Magnan A, Tennant A, Hanson J, Macdonald RN. 1989. Association between asthenia and nutritional status, lean body mass, anemia, psychological status, and tumor mass in patients with advanced breast cancer. J Pain Symptom Manage 4:59-63.
14. Buysse DJ, Reynolds CF III, Monk TH, Berman SR, Kupfer DJ. 1989. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 28:193-213.
15. Buysse DJ, Reynolds CF III, Monk TH, Hoch CC, Yeager AL, Kupfer DJ. 1991. Quantification of subjective sleep quality in healthy elderly men and women using the Pittsburgh Sleep Quality Index (PSQI). Sleep 14:331-8.
16. Carr A, Miller J, Law M, Cooper DA. 2000. A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy syndrome. AIDS 14:F25-32.
17. Cleary PD, Fowler FJ Jr, Weissman J, Massagli MP, Wilson I, Seage GR III, Gatsonis C, Epstein A. 1993. Health-related quality of life in persons with acquired immune deficiency syndrome. Med Care 31:569-80.
18. Clerici M, Trabattoni D, Piconi S, Fusi ML, Ruzzante S, Clerici C. Villa ML. 1997. A possible role for the cortisol/anticortisols imbalance in the progression of human immunodeficiency virus. Psychoneuroendocrinology 22 Suppl 1:S27-31.
19. Cohen PT, Sande MA, Volberding PA. 1999. The AIDS knowledge base: a textbook on HIV disease from the University of California, San Francisco and San Francisco General Hospital. 3rd ed. Philadelphia: Lippincott, Williams & Wilkins.
20. Cole RJ, Kripke DF, Gruen W, Mullaney DJ, Gillin JC. 1992. Automatic sleep/wake identification from wrist activity. Sleep 15:461-9.
21. Cunningham WE, Shapiro MF, Hays RD, Dixon WJ, Visscher BR, George WL, Ettl MK, Beck CK. 1998. Constitutional symptoms and health-related quality of life in patients with symptomatic HIV disease. Am J Med 104;129-36.
22. Curt G, Johnston PG. 2003. Cancer fatigue: the way forward. Oncologist 8 Suppl 1:27-30.
23. Darko DF, McCutchan JA, Kripke DF, Gillin JC, Golshan S. 1992. Fatigue, sleep disturbance, disability, and indices of progression of HIV infection. Am J Psychiatry 149:514-20.
24. Darko DF, Miller JC, Gallen C, White J, Koziol J, Brown SJ, and others. 1995. Sleep electroencephalogram delta-frequency amplitude, night plasma levels of tumor necrosis factor alpha, and human immunodeficiency virus infection. Proc Natl Acad Sci U S A 92:12080-4.
25. Darko DF, Mitler MM, Henriksen SJ. 1995. Lentiviral infection, immune response peptides and sleep. Adv Neuroimmunol 5:57-77.
26. Darko DF, Mitler MM, Miller JC. 1998. Growth hormone, fatigue, poor sleep, and disability in HIV infection. Neuroendocrinology 67:317-24.
27. de Boer JB, van Dam FS, Sprangers MA, Frissen PH, Lange JM. 1993. Longitudinal study on the quality of life of symptomatic HIV-infected patients in a trial of zidovudine versus zidovudine and interferon-alpha. AIDS 7:947-53.
28. Delgado J, Harris M, Tesiorowski A, Montaner JS. 2001. Symptomatic elevations of lactic acid and their response to treatment manipulation in human immunodeficiency virus-infected persons: a case series. Clin Infect Dis 33:2072-4.
29. Doweiko JP, Groopman JE. 1998. Hamtologic manifestations of HIV infection. In Wormser GP, editor. AIDS and other manifestations of HIV infection. Philadelphia: Lippincott-Raven. p 541-57.
30. Duran S, Spire B, Raffi F, Walter V, Bouhour D, Journot V, Cailleton V, Leport C, Moatti JP. 2001. Self-reported symptoms after initiation of a protease inhibitor in HIV-infected patients and their impact on adherence to HAART. HIV Clin Trials 2:38-45.
31. Eller LS. 2001. Quality of life in persons living with HIV Clin Nurs Res 10:401-23.
32. Enwonwu CO, Meeks VI, Sawiris PG. 1996. Elevated cortisol levels in whole saliva in HIV infected individuals. Eur J Oral Sci 104:322-4.
33. Ferrando S, Evans S, Goggin K, Sewell M, Fishman B, Rabkin J. 1998. Fatigue in HIV illness: relationship to depression, physical limitations, and disability. Psychosom Med 60:759-64.
34. Fleishman JA, Crystal S. 1998. Functional status transitions and survival in HIV disease: evidence from the AIDS Costs and Service Utilization Survey. Med Care 36:533-43.
35. Gielen AC, McDonnell KA, Wu AW, O'Campo P, Faden R. 2001. Quality of life among women living with HIV: the importance violence, social support, and self care behaviors. Soc Sci Med 52:315-22.
36. Grady C, Anderson R, Chase GA. 1998. Fatigue in HIV-infected men receiving investigational interleukin-2. Nurs Res 47:227-34.
37. Groopman JE. 1998. Fatigue in cancer and HIV/AIDS. Oncology (Huntingt) 12:335-44.
38. Hagberg L, Janson GL. 2001. Clinical and laboratory signs of mitochondrial dysfunction secondary to nucleoside analogue antiretroviral therapy are reversible. Scand J Infect Dis 33:558.
39. Hart LK, Freel MI, Milde FK. 1990. Fatigue. Nurs Clin North Am 25:967-76.
40. Hoover DR, Saah AJ, Bacellar H, Murphy R, Visscher B, Anderson R, Kaslow RA. 1993. Signs and symptoms of "asymptomatic" HIV-1 infection in homosexual men. Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr 6:66-71.
41. Houston TK, Cooper LA, Ford DE. 2002. Internet support groups for depression: a 1-year prospective cohort study. Am J Psychiatry 159:2062-8.
42. Houston TK, Cooper LA, Vu HT, Kahn J, Toser J, Ford DE. 2001. Screening the public for depression through the Internet. Psychiatr Serv 52:362-7.
43. Johns MW. 1991. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14:540-5.
44. Justice AC, Rabeneck L, Hays RD, Wu AW, Bozzette SA. 1999. Sensitivity, specificity, reliability, and clinical validity of provider-reported symptoms: a comparison with self-reported symptoms. Outcomes Committee of the AIDS Clinical Trials Group. J Acquir Immune Defic Syndr 21:126-33.
45. Kalichman SC, Sikkema KJ, Somlai A. 1995. Assessing persons with human immunodeficiency virus (HIV) infection using the Beck Depression Inventory: disease processes and other potential confounds. J Pers Assess 64:86-100.
46. Kaslow RA, Phair JP, Friedman HB, Lyter D, Solomon RE, Dudley J, Polk BF, Blackwelder W. 1987. Infection with the human immunodeficiency virus: clinical manifestations and their relationship to immune deficiency. A report from the Multicenter AIDS Cohort Study. Ann Intern Med 107:474-80.
47. Kessler HA, Johnson J, Follansbee S, Sension MG, Mildvan D, Sepulveda GE, Bellos NC, Hetherington SV. 2002. Abacavir expanded access program for adult patients infected with human immunodeficiency virus type 1. Clin Infect Dis 34:535-42.
48. Lang W, Anderson RE, Perkins H, Grant RM, Lyman D, Winkelstein W Jr, Royce R, Levy JA. 1987. Clinical, immunologic, and serologic findings in men at risk for acquired immunodeficiency syndrome. The San Francisco Men's Health Study. JAMA 257:326-30.
49. Lavreys L, Baeten JM, Overbaugh J, Panteleeff DD, Chohan BH, Richardson BA, Mandaliya K, Ndinya-Achola JO, Kreiss JK. 2002. Virus load during primary Human Immunodeficiency Virus (HIV) type 1 infection is related to the severity of acute HIV illness in Kenyan women. Clin Infect Dis 35:77-81.
50. Lee KA, Portillo CJ, Miramontes H. 1999. The fatigue experience for women with human immunodeficiency virus. J Obstet Gynecol Neonatal Nurs 28:193-200.
51. Levenstein S, Prantera C, Varvo V, Scribano ML, Berto E, Luzi C, Andreoli A. 1993. Development of the Perceived Stress Questionnaire: a new tool for psychosomatic research. J Psychosom Res 37:19-32.
52. Longo MB, Spross JA, Locke AM. 1990. Identifying major concerns of persons with acquired immunodeficiency syndrome: a replication. Clin Nurse Spec 4:21-6.
53. Lyketsos CG, Hoover DR, Guccione M, Dew MA, Wesch JE, Bing EG, Triesman GJ. 1996. Changes in depressive symptoms as AIDS develops. The Multicenter AIDS Cohort Study. Am J Psychiatry 153:1430-7.
54. Macallan DC, Noble C, Baldwin C, Jebb SA, Prentice AM, Coward WA, Sawyer MB, McManus TJ, Griffin GE. 1995. Energy expenditure and wasting in human immunodeficiency virus infection. N Engl J Med 333:83-8.
55. Malarkey WB, Pearl DK, Demers LM, Kiecolt-Glaser JK, Glaser R. 1995. Influence of academic stress and season on 24-hour mean concentrations of ACTH, cortisol, and beta-endorphin. Psychoneuroendocrinology 20:499-508.
56. Markham PD, Salahuddin SZ, Veren K, Orndorff S, Gallo RC. 1986. Hydrocortisone and some other hormones enhance the expression of HTLV-III. Int J Cancer 37:67-72.
57. McMahon D, Lederman M, Haas DW, Haubrich R, Stanford J, Cooney E, Horton J, Kelleher D, Ross L, Cutrell A, and others. 2001. Antiretroviral activity and safety of abacavir in combination with selected HIV-1 protease inhibitors in therapy-naive HIV-1-infected adults. Antivir Ther 6:105-14.
58. Mocroft A, Kirk O, Barton SE, Dietrich M, Proenca R, Colebunders R, Pradier C, d'Arminio Monteforte A, Ledergerber B, Lundgren JD. 1999. Anaemia is an independent predictive marker for clinical prognosis in HIV-infected patients from across Europe. EuroSIDA Study Group. AIDS 13:943-50.
59. Molassiotis A, Nahas-Lopez V, Chung WY, Lam SW, Li CK, Lau TF. 2002. Factors associated with adherence to antiretroviral medication in HIV-infected patients. Int J STD AIDS 13:301-10.
60. Monreal MT, da Cunha RV Trinca LA. 2002. Compliance to antiretroviral medication as reported by AIDS patients assisted at the University Hospital of the Federal University of Mato Grosso do Sul. Braz J Infect Dis 6:8-14.
61. Morant R. 1996. Asthenia: an important symptom in cancer patients. Cancer Treat Rev 22 Suppl A: 117-22.
62. Moyle G. 2002. Anaemia in persons with HIV infection: prognostic marker and contributor to morbidity. AIDS Rev 4:13-20.
63. National Center for Health Statistics. 1996. Vital and health statistics series 10, number 200: current estimates from the national health survey, 1996. Atlanta (GA): Centers for Disease Control and Prevention.
64. Newshan G, Bennett J, Holman S. 2002. Pain and other symptoms in ambulatory HIV patients in the age of highly active antiretroviral therapy. J Assoc Nurses AIDS Care 13:78-83.
65. Nokes KM, Wheeler K, Kendrew J. 1994. Development of an HIV assessment tool. Image J Nurs Sch 26:133-8.
66. O'Brien ME, Pheifer WG. 1993. Physical and psychosocial nursing care for patients with HIV infection. Nurs Clin North Am 28:303-16.
67. O'Dell MW, Meighen M, Riggs RV. 1996. Correlates of fatigue in HIV infection prior to AIDS: a pilot study. Disabil Rehabil 18:249-54.
68. Ostrow DE, Fox KJ, Chmiel JS, Silvestre A, Visscher BR, Vanable PA, Jacobson LP, Strathdee SA. 2002. Attitudes towards highly active antiretroviral therapy are associated with sexual risk taking among HIV-infected and uninfected homosexual men. AIDS 16:775-80.
69. Parikh RM, Eden DT, Price TR, Robinson RG. 1988. The sensitivity and specificity of the Center for Epidemiologic Studies Depression Scale in screening for post-stroke depression. Int J Psychiatry Med 18:169-81.
70. Perkins DO, Leserman J, Stern RA, Baum SF, Liao D, Golden RN, Evans DL. 1995. Somatic symptoms and HIV infection: relationship to depressive symptoms and indicators of HIV disease. Am J Psychiatry 152:1776-81.
71. Perry S, Fishman B, Jacobsberg E, Frances A. 1992. Relationships over 1 year between lymphocyte subsets and psychosocial variables among adults with infection by human immunodeficiency virus. Arch Gen Psychiatry 49:396-401.
72. Phillips KD, Groer M. 2002. Differentiation and treatment of anemia in HIV disease. J Assoc Nurses AIDS Care 13:47-68.
73. Piedrola G, Casado JE, Lopez E, Moreno A, Perez-Elias MJ, Garcia-Robles R. 1996. Clinical features of adrenal insufficiency in patients with acquired immunodeficiency syndrome. Clin Endocrinol 45:97-101.
74. Piper BF. 1989. Fatigue. In: Funk SG, Tournquist EM, Champagne E, Copp A, Wiese RA, editors. Key aspects of comfort: management of pain, fatigue, and nausea. New York: Springer. p 199-208.
75. Piper BF, Dibble SL, Dodd MJ, Weiss MC, Slaughter RE, Paul SM. 1998. The revised Piper Fatigue Scale: psychometric evaluation in women with breast cancer. Oncol Nurs Forum 25:677-84.
76. Piper BF, Lindsey AM, Dodd MJ. 1987. Fatigue mechanisms in cancer patients: developing nursing theory. Oncol Nurs Forum 14:17-23.
77. Rabkin JG, Ferrando SJ, Wagner GJ, Rabkin R. 2000. DHEA treatment for HIV+ patients: effects on mood, androgenic and anabolic parameters. Psychoneuroendocrinology 25:53-68.
78. Rabkin JG, Williams JB, Remien RH, Goetz R, Kertzner R, Gorman JM. 1991. Depression, distress, lymphocyte subsets, and human immunodeficiency virus symptoms on two occasions in HIV-positive homosexual men. Arch Gen Psychiatry 48:111-9.
79. Radloff LS. 1977. The CES-D Scale: a self-report depression scale for research in the general population. Applied Psychological Measurement 1:385-401.
80. Rhodes VA, Watson PM, Hanson BM. 1988. Patients' descriptions of the influence of tiredness and weakness on self-care abilities. Cancer Nurs 11:186-94.
81. Rondanelli M, Solerte SB, Fioravanti M, Scevola D, Locatelli M, Minoli L, Ferrari E. 1997. Circadian secretory pattern of growth hormone, insulin-like growth factor type I, cortisol, adrenocorticotropic hormone, thyroid-stimulating hormone, and prolactin during HIV infection. AIDS Res Hum Retroviruses 13:1243-9.
82. Rose L, Pugh LC, Lears K, Gordon DL. 1998. The fatigue experience: persons with HIV infection. J Adv Nurs 28:295-304.
83. Sewell MC, Goggin KJ, Rabkin JG, Ferrando SJ, McElhiney MC, Evans S. 2000. Anxiety syndromes and symptoms among men with AIDS: a longitudinal controlled study. Psychosomatics 41:294-300.
84. Singh N, Squier C, Sivek C, Wagener MM, Yu VL. 1997. Psychological stress and depression in older patients with intravenous drug use and human immunodeficiency virus infection: implications for intervention. Int J STD AIDS 8:251-5.
85. Spielberger CD, Gorsuch F, Lushene R. 1971. STAI manual for S-T-A-I ("self-evaluation questionnaire"). Palo Alto (CA): Consulting Psychologists Press.
86. Steptoe A, Wardle J, Lipsey Z, Mills R, Oliver G, Jarvis M, Kirschbaum C. 1998. A longitudinal study of work load and variations in psychological well-being, cortisol, smoking, and alcohol consumption. Ann Behav Med 20:84-91.
87. Sullivan PS, Dworkin MS, the Adult and Adolescent Spectrum of HIV Disease Investigators. 2003. Prevalence and correlates of fatigue among persons with HIV infection. J Pain Symptom Manage 25:329-33.
88. Vlahov D, Munoz A, Solomon L, Astemborski J, Lindsay A, Anderson J, Galai N, Nelson KE. 1994. Comparison of clinical manifestations of HIV infection between male and female injecting drug users. AIDS 8:819-23.
89. Walker K, McGown A, Jantos M, Anson J. 1997. Fatigue, depression, and quality of life in HIV-positive men. J Psychosoc Ment Health Serv 35:32-40.
90. Wilson IB, Cleary PD. 1996. Clinical predictors of functioning in persons with acquired immunodeficiency syndrome. Med Care 34:610-23.
91. Winningham ML, Nail LM, Burke MB, Brophy L, Cimprich B, Jones LS, Pickard-Holley S, Rhodes V, St. Pierre B, Beck S, and others. 1994. Fatigue and the cancer experience: the state of the knowledge. Oncol Nurs Forum 21:23-36.
92. Wollmann T, Barroso J, Monton F, Nieto A. 2002. Neuropsychological test performance of patients with Friedreich's ataxia. J Clin Exp Neuropsychol 24:677-86.
93. Yellen SB, Cella DF, Webster K, Blendowski C, Kaplan E. 1997. Measuring fatigue and other anemia-related symptoms with the Functional Assessment of Cancer Therapy (FACT) measurement system. J Pain Symptom Manage 13:63-74.