Effect of heterogeneity in radiosensitivity on LQ based isoeffect formalism for low α/β cancers

Acta Oncologica

Volumn 43, Issue 5, 2004, Pages 499-502

  Moiseenko, Vitali ^a  

^a Fraser Valley Cancer Centre   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DOSIMETRY; MATHEMATICAL ANALYSIS; NORMAL DISTRIBUTION; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE FRACTIONATION; RADIOSENSITIVITY;

DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; MALE; PROBABILITY; PROSTATIC NEOPLASMS; RADIATION TOLERANCE; RADIOTHERAPY DOSAGE;

EID: 3843096165     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/02841860410032777     Document Type: Article

References (5)

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2. Brenner DJ, Martinez AA, Edmundson GK, Mitchell C, Thames HD, Armour EP. Direct evidence that prostate tumors show high sensitivity to fractionation (low alpha/beta ratio), similar to late-responding normal tissue. Int J Radiat Oncol Biol Phys 2002; 52: 6-13.
3. Nahum AE, Movsas B, Horwitz EM, Stobbe CC, Chapman JD. Incorporating clinical measurements of hypoxia into tumor control modeling of prostate cancer: implications for the alpha/beta ratio. Int J Radiat Oncol Biol Phys 2003; 57: 391-401.
4. Roberts SA, Hendry JH. A realistic closed-form radiobiological model of clinical tumor-control data incorporating intertumor heterogeneity. Int J Radiat Oncol Biol Phys 1998; 41: 689-99.
5. Deasy J. Tumor control probability models for nonuniform dose distributions. In: Paliwal BR, Fowler JF, Herbert DE, Mehta MP, editors. Volume & kinetics in tumor control & normal tissue complications. Madison: Medical Physics Publishing; 1998. p. 65-85.