Comparison of genetic polymorphism of cytochrome CYP2C19 between men and women in Chinese population

Yaoxue Xuebao

Volumn 39, Issue 3, 2004, Pages 161-163

  Fu, Liang Qing ^a   Huang, Feng ^a   Wu, De Zheng ^a   Guo, Jun Hua ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

CYP2C19; Cytochrome; Genetic polymorphism; Genotype

Indexed keywords

CYTOCHROME P450 2C19; CYP2C19 PROTEIN, HUMAN; MIXED FUNCTION OXIDASE; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CHINESE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MALE; NORMAL HUMAN; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; WILD TYPE; ADOLESCENT; ADULT; AGED; ASIAN; CHINA; GENE FREQUENCY; GENETICS; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; ARYL HYDROCARBON HYDROXYLASES; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MIXED FUNCTION OXYGENASES; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SEX FACTORS;

EID: 3843092910     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Xiao ZS, Goldstein JA, Xie HG, et al. Differences in the incidence of the polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele [J]. J Pharmcol Exp Ther, 1997,281(1):604-609.
2. Xie HG, Huang SL, Xu ZH, et al. Evidence for the effect of gender on activity of S-mephenytoin 4′-hydroxylase (CYP2C19) in a Chinese population [J]. Pharmacogenetics, 1997,7(2):115-119.
3. Kupfer A, Preisig R. Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man [J]. Eur J Clin Pharmacol, 1984,26:753-759.
4. Hadidi HH, Irshaid YM, Woosley RL, et al. (S)-Mephenytoin hydroxylation phenotypes in a Jordanian population [J]. Clin Pharmacol Ther, 1995,58:542-547.
5. Evans DAP, Krahn P, Narayanan N. The mephenytoin (cytochrome P4502C19) and dextromethorphan (cytochrome P4502D6) polymorphisms in Saudi Arabians and Filipinos [J]. Pharmacogenetics, 1995,5:64-71.
6. Ededi Ti, Hajiloo L, Butler M, et al. (S)-Mephentoin 4′- hydroxylation in African-Americans (Abstract) [J]. J Clin Pharmacol, 1994,34:1032-1036.