The ethics of clinical innovation in psychopharmacology: Challenging traditional bioethics

Philosophy, Ethics, and Humanities in Medicine

Volumn 2, Issue 1, 2007, Pages

  Nassir, S Nassir ^a   Goodwin, Frederick K ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROLEPTIC AGENT;

CLASSIFICATION; ETHICS; HISTORY; HUMAN; MEDICAL RESEARCH; MENTAL DISEASE; PSYCHOPHARMACOLOGY; REVIEW;

ANTIPSYCHOTIC AGENTS; BIOMEDICAL RESEARCH; HISTORY, 20TH CENTURY; HUMANS; MENTAL DISORDERS; PSYCHOPHARMACOLOGY;

EID: 38349166984     PISSN: None     EISSN: 17475341     Source Type: Journal    
DOI: 10.1186/1747-5341-2-26     Document Type: Review

References (25)

1. Cade JF Contemporary challenges in psychiatry Aust N Z J Psychiatry 1971, 5:10-7 5291035
2. American Psychiatric Association The Principles of Medical Ethics, with annotations especially applicable to psychiatry Washington DC: American Psychiatric Press 2001
3. The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research 1979
4. Blackwell B The process of discovery Discoveries in biological psychiatry Philadelphia: Lippincott Ayd F, Blackwell B 1970, 11-29
5. Deniker P Introduction of neuroleptic chemotherapy into psychiatry Discoveries in biological psychiatry Philadelphia: Lippincott Ayd F, Blackwell B 1970, 155-164
6. Kuhn R The imipramine story Discoveries in biological psychiatry Philadelphia: Lippincott Ayd F, Blackwell B 1970, 205-217
7. Cade J The story of lithium Discoveries in biological psychiatry Philadelphia: Lippincott Ayd F, Blackwell B 1970, 218-229
8. Okuma T Therapeutic and prophylactic effects of carbamazepine in bipolar disorders Pyschiatr Clin North Am 1983, 6:157-174
9. Sackett D Strauss S Richardson W Rosenberg W Haynes R Evidence Based Medicine London: Churchill Livingstone 2 2000
10. Rafaelsen OJ Ethics of psychopharmacological research Prog Neuropsychopharmacol 1979, 3:281-5 10.1016/0364-7722(79)90092-4 400985
11. Shepherd M The use and abuses of drugs in psychiatry Lancet 1970, 1:31-3 10.1016/S0140-6736(70)90538-6 4188353
12. Plutchik R Platman SR Fieve RR Three alternatives to the double-blind Arch Gen Psychiatry 1969, 20:428-32 4886346
13. Forster EF Some ethical considerations in the development of psychopharmacological research and practice in the future Prog Neuropsychopharmacol 1979, 3:277-80 10.1016/0364-7722(79)90091-2 400984
14. Gentili C Ferrari G Ethical problems in psychopharmacological research Prog Neuropsychopharmacol 1979, 3:287-91 10.1016/0364-7722(79)90093-6 400986
15. Cole JO Research barriers in psychopharmacology Am J Psychiatry 1977, 134:896-8 879353
16. Stahl SM Needs and opportunities for innovation in psychopharmacology J R Soc Med 1987, 80:413-7 1290900 3656311
17. Young SN Risk in research-from the Nuremberg Code to the tri-council code: Implications for clinical trials of psychotropic drugs J Psychiatry Neurosci 1998, 23:149-55 1188921 9595888
18. Charlton BG Psychopharmacology and the human condition J R Soc Med 1998, 91:599-601 1296960 10325883
19. Young SN Why psychopharmacological researchers need to become more vocal and thoughtful in debating issues in research ethics J Psychiatry Neurosci 1998, 23:147-8 1188920 9595887
20. Leon CA Ethical aspects of psychopharmacology Prog Neuropsychopharmacol 1979, 3:297-301 10.1016/0364-7722(79)90095-X 400988
21. Muller-Oerlinghausen B Ethical problems in clinical psychopharmacology Int J Clin Pharmacol Biopharm 1978, 16:443-50 700905
22. Alexander L New dimensions in legal and ethical concepts for human research. 2. Special problems of medical disciplines. Psychiatry: methods and processes for investigation of drugs Ann N Y Acad Sci 1970, 169:344-50 10.1111/j.1749-6632.1970.tb54741.x 4907478
23. Katz MM Ethical issues in the use of human subjects in psychopharmacologic research Am Psychol 1967, 22:360-3 10.1037/h0024884 6041094
24. Kanigel R Apprentice to genius: The making of a scientific dynasty New York: Macmillan; 1986
25. Office of Human Subjects Research Guidelines for the Conduct of Research Involving Human Subjects at the National Institutes of Health 1986 http://www.nihtraining.com/ohsrsite/guidelines/GrayBooklet82404.pdf