The loss of the PDE6 deactivating enzyme, RGS9, results in precocious light adaptation at low light levels

Journal of Vision

Volumn 8, Issue 1, 2008, Pages

  Stockman, Andrew ^a   Smithson, Hannah E ^b   Webster, Andrew R ^c   Holder, Graham E ^c   Rana, Naheed A ^d   Ripamonti, Caterina ^a   Sharpe, Lindsay T ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b DURHAM UNIVERSITY   (United Kingdom)

^c MOORFIELDS EYE HOSPITAL   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Bradyopsia; Cone photoreceptor; Light adaptation; PDE6; Photopigment; RGS9; Vision; Visual transduction

Indexed keywords

MEMBRANE PROTEIN; PHOSPHODIESTERASE 6; R9AP PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; COMPARATIVE STUDY; CONTRAST SENSITIVITY; CRITICAL FLICKER FUSION; ENZYME ACTIVATION; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; MIDDLE AGED; MISSENSE MUTATION; PHYSIOLOGY; RETINA; VISUAL ADAPTATION;

ADAPTATION, OCULAR; ADULT; CONTRAST SENSITIVITY; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 6; ENZYME ACTIVATION; FEMALE; FLICKER FUSION; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION, MISSENSE; RETINA;

EID: 38349162817     PISSN: None     EISSN: 15347362     Source Type: Journal    
DOI: 10.1167/8.1.10     Document Type: Article

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