메뉴 건너뛰기




Volumn 10, Issue 1, 2008, Pages 45-53

Prevention of graft vs. host disease with alemtuzumab 'in the bag' decreases early toxicity of stem cell transplantation and in multiple myeloma is associated with improved long-term outcome

Author keywords

CD52; Graft vs. host disease; Plasma cell malignancies; T cell depletion; Total lymphoid irradiation

Indexed keywords

ALEMTUZUMAB; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPHOTERICIN B; ANTIBIOTIC AGENT; BUSULFAN; CEPHALOSPORIN DERIVATIVE; CORTICOSTEROID; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DEXAMETHASONE; DOXORUBICIN; GANCICLOVIR; GRANULOCYTE COLONY STIMULATING FACTOR; HUMAN ALBUMIN; MELPHALAN; OFLOXACIN; POLYPEPTIDE ANTIBIOTIC AGENT; PREDNISONE; PYRROLE DERIVATIVE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; VALACICLOVIR; VALGANCICLOVIR; VINCRISTINE;

EID: 38349160448     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1080/14653240701732771     Document Type: Article
Times cited : (7)

References (34)
  • 1
    • 6444244370 scopus 로고    scopus 로고
    • Melphalan-prednisone versus alternating combination VAD/MP or VND/MP as primary therapy for multiple myeloma: Final analysis of a randomized clinical study
    • Cavo, M., Benni, M. and Ronconi, S. (2002) Melphalan-prednisone versus alternating combination VAD/MP or VND/MP as primary therapy for multiple myeloma: Final analysis of a randomized clinical study. Haematologica, 87, pp. 934-942.
    • (2002) Haematologica , vol.87 , pp. 934-942
    • Cavo, M.1    Benni, M.2    Ronconi, S.3
  • 2
    • 0019929958 scopus 로고
    • Comparison of oral melphalan, CCNU, and BCNU with and without vincristine and prednisone in the treatment of multiple myeloma: Cancer and Leukemia Group B experience
    • Cornwell, GG, Pajak, TF and Kochwa, S. (1982) Comparison of oral melphalan, CCNU, and BCNU with and without vincristine and prednisone in the treatment of multiple myeloma: Cancer and Leukemia Group B experience. Cancer, 50, pp. 1669-1675.
    • (1982) Cancer , vol.50 , pp. 1669-1675
    • Cornwell, G.G.1    Pajak, T.F.2    Kochwa, S.3
  • 3
    • 0021619890 scopus 로고
    • Multiple myeloma
    • Oken, MM. (1984) Multiple myeloma. Med Clin North Am, 68, pp. 757-787.
    • (1984) Med Clin North Am , vol.68 , pp. 757-787
    • Oken, M.M.1
  • 4
    • 9244263575 scopus 로고    scopus 로고
    • High-dose therapy followed by autologous hematopoietic stem-cell infusion for patients with multiple myeloma
    • Bensinger, WI, Rowley, SD and Demire, T. (1996) High-dose therapy followed by autologous hematopoietic stem-cell infusion for patients with multiple myeloma. J Clin Oncol, 14, pp. 1447-1456.
    • (1996) J Clin Oncol , vol.14 , pp. 1447-1456
    • Bensinger, W.I.1    Rowley, S.D.2    Demire, T.3
  • 5
    • 0032929769 scopus 로고    scopus 로고
    • Total therapy with tandem transplants for newly diagnosed multiple myeloma
    • Barlogie, B., Jagannath, S. and Desikan, KR (1999) Total therapy with tandem transplants for newly diagnosed multiple myeloma. Blood, 93, pp. 55-65.
    • (1999) Blood , vol.93 , pp. 55-65
    • Barlogie, B.1    Jagannath, S.2    Desikan, K.R.3
  • 6
    • 38349144179 scopus 로고    scopus 로고
    • Autologous stem cell transplantation in multiple myeloma: An update of the EBMT registry
    • Bjorkstrand, B., Hagman, A. and Ljungman, P. (2001) Autologous stem cell transplantation in multiple myeloma: An update of the EBMT registry. European Journal of Haematology, pp. 199-202.
    • (2001) European Journal of Haematology , pp. 199-202
    • Bjorkstrand, B.1    Hagman, A.2    Ljungman, P.3
  • 7
    • 0033764086 scopus 로고    scopus 로고
    • High-dose therapy autotransplantation/intensification vs. continued standard chemotherapy in multiple myeloma in first remission: Results of a non-randomized study from a single institution
    • Blade, J., Esteve, J. and Rives, S. (2000) High-dose therapy autotransplantation/intensification vs. continued standard chemotherapy in multiple myeloma in first remission: Results of a non-randomized study from a single institution. Bone Marrow Transplant, 26, pp. 845-849.
    • (2000) Bone Marrow Transplant , vol.26 , pp. 845-849
    • Blade, J.1    Esteve, J.2    Rives, S.3
  • 8
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma: Intergroupe Francais du Myelome
    • Attal, M., Harousseau, JL and Stoppa, AM (1996) A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma: Intergroupe Francais du Myelome. New Engl J Med, 335, pp. 91-97.
    • (1996) New Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3
  • 9
    • 0012689130 scopus 로고    scopus 로고
    • Impact on survival of high-dose therapy with autologous stem cell support in patients younger than 60 years with newly diagnosed multiple myeloma: A population-based study, Nordic Myeloma Study Group
    • Lenhoff, S., Hjorth, M. and Holmberg, E. (2000) Impact on survival of high-dose therapy with autologous stem cell support in patients younger than 60 years with newly diagnosed multiple myeloma: A population-based study, Nordic Myeloma Study Group. Blood, 95, pp. 7-11.
    • (2000) Blood , vol.95 , pp. 7-11
    • Lenhoff, S.1    Hjorth, M.2    Holmberg, E.3
  • 10
    • 0028904407 scopus 로고
    • High-dose sequential chemoradiotherapy in multiple myeloma: Residual tumor cells are detectable in bone marrow and peripheral blood cell harvests and after autografting
    • Corradini, P., Voena, C. and Astolfi, M. (1995) High-dose sequential chemoradiotherapy in multiple myeloma: Residual tumor cells are detectable in bone marrow and peripheral blood cell harvests and after autografting. Blood, 85, pp. 1596-1602.
    • (1995) Blood , vol.85 , pp. 1596-1602
    • Corradini, P.1    Voena, C.2    Astolfi, M.3
  • 11
    • 0035449067 scopus 로고    scopus 로고
    • Purging of autologous peripheral-blood stem cells using CD34 selection does not improve overall or progression-free survival after high-dose chemotherapy for multiple myeloma: Results of a multicenter randomized controlled trial
    • Stewart, K., Vescio, R. and Schiller, G. (2001) Purging of autologous peripheral-blood stem cells using CD34 selection does not improve overall or progression-free survival after high-dose chemotherapy for multiple myeloma: Results of a multicenter randomized controlled trial. J Clin Oncol, 19, pp. 3771-3779.
    • (2001) J Clin Oncol , vol.19 , pp. 3771-3779
    • Stewart, K.1    Vescio, R.2    Schiller, G.3
  • 12
    • 0030043438 scopus 로고    scopus 로고
    • Graft-versus-myeloma effect: Proof of principle
    • Tricot, G., Vesole, DH and Jagannath, S. (1996) Graft-versus-myeloma effect: Proof of principle. Blood, 87, pp. 1196-1198.
    • (1996) Blood , vol.87 , pp. 1196-1198
    • Tricot, G.1    Vesole, D.H.2    Jagannath, S.3
  • 13
    • 10544228954 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation versus autologous stem cell transplantation in multiple myeloma: A retrospective case-matched study from the European Group for Blood and Marrow Transplantation
    • Bjorkstrand, BB, Ljungman, P. and Svensson, H. (1996) Allogeneic bone marrow transplantation versus autologous stem cell transplantation in multiple myeloma: A retrospective case-matched study from the European Group for Blood and Marrow Transplantation. Blood, 88, pp. 4711-4718.
    • (1996) Blood , vol.88 , pp. 4711-4718
    • Bjorkstrand, B.B.1    Ljungman, P.2    Svensson, H.3
  • 14
    • 0030815867 scopus 로고    scopus 로고
    • Donor leukocyte infusions are effective in relapsed multiple myeloma after allogeneic bone marrow transplantation
    • Lokhorst, HM, Schattenberg, A. and Cornelissen, JJ (1997) Donor leukocyte infusions are effective in relapsed multiple myeloma after allogeneic bone marrow transplantation. Blood, 90, pp. 4206-4211.
    • (1997) Blood , vol.90 , pp. 4206-4211
    • Lokhorst, H.M.1    Schattenberg, A.2    Cornelissen, J.J.3
  • 15
    • 0033844816 scopus 로고    scopus 로고
    • Donor lymphocyte infusions for relapsed multiple myeloma after allogeneic stem-cell transplantation: Predictive factors for response and long-term outcome
    • Lokhorst, HM, Schattenberg, A. and Cornelissen, JJ (2000) Donor lymphocyte infusions for relapsed multiple myeloma after allogeneic stem-cell transplantation: Predictive factors for response and long-term outcome. J Clin Oncol, 18, pp. 3031-3037.
    • (2000) J Clin Oncol , vol.18 , pp. 3031-3037
    • Lokhorst, H.M.1    Schattenberg, A.2    Cornelissen, J.J.3
  • 16
    • 0029834790 scopus 로고    scopus 로고
    • Syngeneic marrow transplantation in patients with multiple myeloma
    • Bensinger, WI, Demirer, T. and Buckner, CD (1996) Syngeneic marrow transplantation in patients with multiple myeloma. Bone Marrow Transplant, 18, pp. 527-531.
    • (1996) Bone Marrow Transplant , vol.18 , pp. 527-531
    • Bensinger, W.I.1    Demirer, T.2    Buckner, C.D.3
  • 17
    • 2642510845 scopus 로고    scopus 로고
    • Campath-1 Abs 'in the bag' for hematological malignancies: The Cape Town experience
    • Novitzky, N., Thomas, V. and Hale, G. (2004) Campath-1 Abs 'in the bag' for hematological malignancies: The Cape Town experience. Cytotherapy, 6, pp. 172-181.
    • (2004) Cytotherapy , vol.6 , pp. 172-181
    • Novitzky, N.1    Thomas, V.2    Hale, G.3
  • 18
    • 0033949148 scopus 로고    scopus 로고
    • CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells
    • Hale, G., Jacobs, P. and Wood, L. (2000) CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells. Bone Marrow Transplant, 26, pp. 69-76.
    • (2000) Bone Marrow Transplant , vol.26 , pp. 69-76
    • Hale, G.1    Jacobs, P.2    Wood, L.3
  • 19
    • 27244447632 scopus 로고    scopus 로고
    • Myeloablative conditioning is well tolerated by older patients receiving T-cell depleted grafts
    • Novitzky, N., Thomas, V. and Hale, G. (2005) Myeloablative conditioning is well tolerated by older patients receiving T-cell depleted grafts. Bone Marrow Transplant, 36, pp. 675-682.
    • (2005) Bone Marrow Transplant , vol.36 , pp. 675-682
    • Novitzky, N.1    Thomas, V.2    Hale, G.3
  • 20
    • 0025348259 scopus 로고
    • The CAMPATH-1 antigen (Cdw 52)
    • Hale, G., Xia, M-Q and Tighe, HP (1990) The CAMPATH-1 antigen (Cdw 52). Tissue Antig, 35, pp. 118-127.
    • (1990) Tissue Antig , vol.35 , pp. 118-127
    • Hale, G.1    Xia, M.-Q.2    Tighe, H.P.3
  • 21
    • 20644460600 scopus 로고    scopus 로고
    • International staging system for multiple myeloma
    • Greipp, PR, Miguel, J San and Durie, BG (2005) International staging system for multiple myeloma. J Clin Oncol, 23, pp. 3412-3420.
    • (2005) J Clin Oncol , vol.23 , pp. 3412-3420
    • Greipp, P.R.1    Miguel, J.2    San Durie, B.G.3
  • 22
    • 0018764526 scopus 로고
    • A modified right atrial catheter for access to the venous system in marrow transplant recipients
    • Hickman, RO, Buckner, CD and Clift, RA (1979) A modified right atrial catheter for access to the venous system in marrow transplant recipients. Surg Gynecol Obstet, 148, pp. 871-875.
    • (1979) Surg Gynecol Obstet , vol.148 , pp. 871-875
    • Hickman, R.O.1    Buckner, C.D.2    Clift, R.A.3
  • 23
    • 0034754677 scopus 로고    scopus 로고
    • Infectious complications following T-cell depleted hematopoietic stem-cell transplantation
    • Novitzky, N. and Rouskova, A. (2001) Infectious complications following T-cell depleted hematopoietic stem-cell transplantation. Cytotherapy, 3, pp. 165-173.
    • (2001) Cytotherapy , vol.3 , pp. 165-173
    • Novitzky, N.1    Rouskova, A.2
  • 24
    • 0025237877 scopus 로고
    • Very low doses of warfarin can prevent thrombosis in central venous catheters
    • Bern, MM, Lokich, JJ and Wallach, SR (1990) Very low doses of warfarin can prevent thrombosis in central venous catheters. A randomized prospective trial. Ann Intern Med, 112, pp. 423-428.
    • (1990) Ann Intern Med , vol.112 , pp. 423-428
    • Bern, M.M.1    Lokich, J.J.2    Wallach, S.R.3
  • 25
    • 0029760436 scopus 로고    scopus 로고
    • The ISHAGE guidelines for CD34+ cell determination by flow cytometry
    • Sutherland, DR, Anderson, L. and Keeney, M. (1996) The ISHAGE guidelines for CD34+ cell determination by flow cytometry. J Hematother, 5, pp. 213-226.
    • (1996) J Hematother , vol.5 , pp. 213-226
    • Sutherland, D.R.1    Anderson, L.2    Keeney, M.3
  • 26
    • 0016187133 scopus 로고
    • Clinical manifestations of graft vs host disease in human recipients of marrow from HLA matched sibling donors
    • Glucksberg, H., Storb, R. and Fefer, A. (1974) Clinical manifestations of graft vs host disease in human recipients of marrow from HLA matched sibling donors. Transplantation, 18, p. 295.
    • (1974) Transplantation , vol.18 , pp. 295
    • Glucksberg, H.1    Storb, R.2    Fefer, A.3
  • 27
    • 0037111832 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
    • Orlowski, RZ, Stinchcombe, TE and Mitchell, BS (2002) Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J Clin Oncol, 20, pp. 4420-4427.
    • (2002) J Clin Oncol , vol.20 , pp. 4420-4427
    • Orlowski, R.Z.1    Stinchcombe, T.E.2    Mitchell, B.S.3
  • 28
    • 0035880229 scopus 로고    scopus 로고
    • Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: Identification of prognostic factors in a phase 2 study of 169 patients
    • Barlogie, B., Desikan, R. and Eddlemon, P. (2001) Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients. Blood, 98, pp. 492-494.
    • (2001) Blood , vol.98 , pp. 492-494
    • Barlogie, B.1    Desikan, R.2    Eddlemon, P.3
  • 29
    • 0003298401 scopus 로고    scopus 로고
    • A phase I trial of oral CC-5013, an immunomodulatory thalidomide derivative, in patients with relapsed and refractory multiple myeloma
    • Richardson, P., Schlossman, R. and Hideshima, T. (2001) A phase I trial of oral CC-5013, an immunomodulatory thalidomide derivative, in patients with relapsed and refractory multiple myeloma. Blood, 98, p. 775a.
    • (2001) Blood , vol.98
    • Richardson, P.1    Schlossman, R.2    Hideshima, T.3
  • 30
    • 10544228954 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation versus autologous stem cell transplantation in multiple myeloma: A retrospective case-matched study from the European Group for Blood and Marrow Transplantation
    • Bjorkstrand, B., Ljungman, P. and Svensson, H. (1996) Allogeneic bone marrow transplantation versus autologous stem cell transplantation in multiple myeloma: A retrospective case-matched study from the European Group for Blood and Marrow Transplantation. Blood, 88, pp. 4711-4718.
    • (1996) Blood , vol.88 , pp. 4711-4718
    • Bjorkstrand, B.1    Ljungman, P.2    Svensson, H.3
  • 31
    • 0038135027 scopus 로고    scopus 로고
    • For the Dutch-Belgian Hemato-Oncology Cooperative Group. Partially T-cell depleted allogeneic stem-cell transplantation for first-line treatment of multiple myeloma: A prospective evaluation of patients treated in the phase III study HOVON 24 MM
    • Lokhorst, HM, Segeren, CM and Verdonck, LF (2003) For the Dutch-Belgian Hemato-Oncology Cooperative Group. Partially T-cell depleted allogeneic stem-cell transplantation for first-line treatment of multiple myeloma: a prospective evaluation of patients treated in the phase III study HOVON 24 MM. J Clin Oncol, 21, pp. 1728-1733.
    • (2003) J Clin Oncol , vol.21 , pp. 1728-1733
    • Lokhorst, H.M.1    Segeren, C.M.2    Verdonck, L.F.3
  • 32
    • 19944410125 scopus 로고    scopus 로고
    • Reduced-intensity transplantation with in vivo T cell depletion and adjuvant dose-escalating donor lymphocyte infusions for chemotherapy-sensitive myeloma: Limited efficacy of graft-versus-tumor activity
    • Peggs, KS, Mackinnon, S. and Williams, CD (2003) Reduced-intensity transplantation with in vivo T cell depletion and adjuvant dose-escalating donor lymphocyte infusions for chemotherapy-sensitive myeloma: Limited efficacy of graft-versus-tumor activity. Biol Blood Marrow Transplant, 9, pp. 257-265.
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 257-265
    • Peggs, K.S.1    Mackinnon, S.2    Williams, C.D.3
  • 33
    • 21144446701 scopus 로고    scopus 로고
    • Outcomes for reduced-intensity allogeneic transplantation for multiple myeloma: An analysis of prognostic factors from the Chronic Leukaemia Working Party of the EBMT
    • Crawley, C., Lalancette, M. and Szydlo, R. (2005) Outcomes for reduced-intensity allogeneic transplantation for multiple myeloma: An analysis of prognostic factors from the Chronic Leukaemia Working Party of the EBMT. Blood, 105, pp. 4532-4539.
    • (2005) Blood , vol.105 , pp. 4532-4539
    • Crawley, C.1    Lalancette, M.2    Szydlo, R.3
  • 34
    • 0038578245 scopus 로고    scopus 로고
    • Pharmacokinetics of alemtuzumab used for in vivo and in vitro T-cell depletion in allogeneic transplantations: Relevance for early adoptive immunotherapy and infectious complications
    • Morris, EC, Rebello, P. and Thomson, KJ (2003) Pharmacokinetics of alemtuzumab used for in vivo and in vitro T-cell depletion in allogeneic transplantations: Relevance for early adoptive immunotherapy and infectious complications. Blood, 102, pp. 404-406.
    • (2003) Blood , vol.102 , pp. 404-406
    • Morris, E.C.1    Rebello, P.2    Thomson, K.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.