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1342281273
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The integration of pharmacokinetics and pharmacodynamics: Understanding dose-response
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Abdel-Rahman, S. M., & Kauffman, R. E. (2004). The integration of pharmacokinetics and pharmacodynamics: Understanding dose-response. Annual Review of Pharmacology and Toxicology, 44, 111-136.
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Annual Review of Pharmacology and Toxicology
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Abdel-Rahman, S.M.1
Kauffman, R.E.2
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2
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1242277349
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Uncertainty reduction and characterization of complex environmental fate and transport models: An empirical Bayesian framework incorporating the Stochastic Response Surface Method
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Balakrishnan, S., Roy, A., Ierapetritou, M. G., Flach, G. P., & Georgopoulos, P. G. (2003). Uncertainty reduction and characterization of complex environmental fate and transport models: An empirical Bayesian framework incorporating the Stochastic Response Surface Method. Water Resources Research, 39, 1350.
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Water Resources Research
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Balakrishnan, S.1
Roy, A.2
Ierapetritou, M.G.3
Flach, G.P.4
Georgopoulos, P.G.5
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3
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19744365656
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A comparative assessment of efficient uncertainty analysis techniques for environmental fate and transport models: Application to the FACT model
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Balakrishnan, S., Roy, A., Ierapetritou, M. G., Flach, G. P., & Georgopoulos, P. G. (2005). A comparative assessment of efficient uncertainty analysis techniques for environmental fate and transport models: Application to the FACT model. Journal of Hydrology, 307, 204-218.
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Journal of Hydrology
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Balakrishnan, S.1
Roy, A.2
Ierapetritou, M.G.3
Flach, G.P.4
Georgopoulos, P.G.5
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5
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0036843965
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Gene networks: How to put the function in genomics
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Brazhnik, P., de la Fuente, A., & Mendes, P. (2002). Gene networks: How to put the function in genomics. Trends Biotechnol, 20, 467-472.
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Trends Biotechnol
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Brazhnik, P.1
De La Fuente, A.2
Mendes, P.3
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6
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38349188348
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Prepared for American Chemistry Council Long Range Research Initiative Team by Battelle Pacific Northwest Division. Arlington, Virginia. Richland, WA: PNWD (PNWD-3184)
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Buck, J. W., Tolle, D. A., Whelan, G., Mast, T. J., Peffers, M. S., Evers, D. P., et al. (2003). Design of the comprehensive chemical exposure framework and identification of research needs for American Chemistry Council. Prepared for American Chemistry Council Long Range Research Initiative Team by Battelle Pacific Northwest Division. Arlington, Virginia. Richland, WA: PNWD (PNWD-3184).
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(2003)
Design of the Comprehensive Chemical Exposure Framework and Identification of Research Needs for American Chemistry Council
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Buck, J.W.1
Tolle, D.A.2
Whelan, G.3
Mast, T.J.4
Peffers, M.S.5
Evers, D.P.6
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10
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0842279654
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Greener Management International UK
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Christensen, F. M., Bruijn, J. H. M. D., Hansen, B. G., Munn, S. J., Sokull-Klüttgen, B., & Pedersen, F. (2003). Assessment tools under the new European Union chemicals policy (pp. 5-19). UK: Greener Management International (Spring 2003).
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Assessment Tools under the New European Union Chemicals Policy
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Christensen, F.M.1
Bruijn, J.H.M.D.2
Hansen, B.G.3
Munn, S.J.4
Sokull-Klüttgen, B.5
Pedersen, F.6
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12
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1642462948
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Computational physiology and the Physiome Project
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Crampin, E. J., Halstead, M., Hunter, P., Nielsen, P., Noble, D., Smith, N., et al. (2004). Computational physiology and the Physiome Project. Experimental Physiology, 89, 1-26.
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Experimental Physiology
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Crampin, E.J.1
Halstead, M.2
Hunter, P.3
Nielsen, P.4
Noble, D.5
Smith, N.6
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13
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0038701000
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Ultrafine particle deposition in humans during rest and exercise
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Daigle, C. C., Chalupa, D. C., Gibb, F. R., Morrow, P. E., Oberdorster, G., Utell, M. J., et al. (2003). Ultrafine particle deposition in humans during rest and exercise. Inhalation Toxicology, 15, 539-552.
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Inhalation Toxicology
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Daigle, C.C.1
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Gibb, F.R.3
Morrow, P.E.4
Oberdorster, G.5
Utell, M.J.6
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14
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33847028671
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Mechanism-based pharmacokinetic-pharmacodynamic modeling: Biophase distribution, receptor theory, and dynamical systems analysis
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Danhof, M., de Jongh, J., De Lange, E. C., Della Pasqua, O., Ploeger, B. A., & Voskuyl, R. A. (2007). Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis. Annual Review of Pharmacology and Toxicology, 47, 357-400.
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Annual Review of Pharmacology and Toxicology
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Danhof, M.1
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De Lange, E.C.3
Della Pasqua, O.4
Ploeger, B.A.5
Voskuyl, R.A.6
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15
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33750810029
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Examining accountability for changes in population exposures to 8-hour ozone standard with implementation of different control strategies
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Foley, G., Georgopoulos, P. G., & Lioy, P. J. (2003). Examining accountability for changes in population exposures to 8-hour ozone standard with implementation of different control strategies. Environmental Science and Technology, 37, 302A-309A.
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Environmental Science and Technology
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Foley, G.1
Georgopoulos, P.G.2
Lioy, P.J.3
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8744269625
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Hospital response to chemical terrorism: Personal protective equipment, training, and operations planning
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Georgopoulos, P. G., Fedele, P., Shade, P., Lioy, P., Hodgson, M., Longmire, J., et al. (2004). Hospital response to chemical terrorism: Personal protective equipment, training, and operations planning. American Journal of Industrial Medicine, 46, 432-445.
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American Journal of Industrial Medicine
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Georgopoulos, P.G.1
Fedele, P.2
Shade, P.3
Lioy, P.4
Hodgson, M.5
Longmire, J.6
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17
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33750722797
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From theoretical aspects of human exposure and dose assessment to computational model implementation: The MOdeling ENvironment for TOtal Risk studies (MENTOR)
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Georgopoulos, P. G., & Lioy, P. J. (2006). From theoretical aspects of human exposure and dose assessment to computational model implementation: The MOdeling ENvironment for TOtal Risk studies (MENTOR). Journal of Toxicology and Environmental Health B - Critical Reviews, 9, 457-483.
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Journal of Toxicology and Environmental Health B - Critical Reviews
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Georgopoulos, P.G.1
Lioy, P.J.2
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18
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0031031089
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An integrated exposure and dose modeling and analysis system. 1. Formulation and testing of microenvironmental and pharmacokinetic components
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Georgopoulos, P. G., Walia, A., Roy, A., & Lioy, P. J. (1997). An integrated exposure and dose modeling and analysis system. 1. Formulation and testing of microenvironmental and pharmacokinetic components. Environmental Science and Technology, 31, 17-27.
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Environmental Science and Technology
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Georgopoulos, P.G.1
Walia, A.2
Roy, A.3
Lioy, P.J.4
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19
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33748715342
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Assessment of human exposure to copper: A case study using the NHEXAS database
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Georgopoulos, P. G., Wang, S. W., Lioy, P. J., Georgopoulos, I. G., & Yononne-Lioy, M. J. (2006). Assessment of human exposure to copper: A case study using the NHEXAS database. Journal of Exposure Science and Environmental Epidemiology, 16, 397-409.
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(2006)
Journal of Exposure Science and Environmental Epidemiology
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Georgopoulos, P.G.1
Wang, S.W.2
Lioy, P.J.3
Georgopoulos, I.G.4
Yononne-Lioy, M.J.5
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20
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27744562249
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A source-to-dose assessment of population exposures to fine PM and ozone in Philadelphia, PA, during a summer 1999 episode
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Georgopoulos, P. G., Wang, S. W., Vyas, V. M., Sun, Q., Burke, J., Vedantham, R., et al. (2005a). A source-to-dose assessment of population exposures to fine PM and ozone in Philadelphia, PA, during a summer 1999 episode. Journal of Exposure Analysis and Environmental Epidemiology, 15, 439-457.
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Journal of Exposure Analysis and Environmental Epidemiology
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Georgopoulos, P.G.1
Wang, S.W.2
Vyas, V.M.3
Sun, Q.4
Burke, J.5
Vedantham, R.6
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21
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38349168012
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Biologically-based modeling of multimedia, multipathway, multiroute population exposures to arsenic
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in press
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Georgopoulos, P. G., Wang, S. W., Yang, Y. C., McCurdy, T., Özkaynak, H., Xue, J., et al. (2007). Biologically-based modeling of multimedia, multipathway, multiroute population exposures to arsenic. Journal of Exposure Science and Environmental Epidemiology (in press).
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Journal of Exposure Science and Environmental Epidemiology
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Georgopoulos, P.G.1
Wang, S.W.2
Yang, Y.C.3
McCurdy, T.4
Özkaynak, H.5
Xue, J.6
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22
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33750819713
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Assessing multimedia/multipathway exposures to arsenic using a mechanistic source-to-dose modeling framework: Case studies employing MENTOR/SHEDS-4M
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Prepared for the US Environmental Protection Agency North Carolina: USEPA
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Georgopoulos, P. G., Wang, S. W., Yang, Y. C., Xue, J., Zartarian, V., McCurdy, T., et al. (2005b). Assessing multimedia/multipathway exposures to arsenic using a mechanistic source-to-dose modeling framework: Case studies employing MENTOR/SHEDS-4M. Prepared for the US Environmental Protection Agency. Technical Report CERM:2005-01. North Carolina: USEPA.
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Technical Report CERM:2005-01
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Georgopoulos, P.G.1
Wang, S.W.2
Yang, Y.C.3
Xue, J.4
Zartarian, V.5
McCurdy, T.6
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23
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38349160921
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Source-to-dose modeling of long-term population exposures to reactive and non-reactive air pollutants: Indoor and outdoor contributions
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Paper presented Tucson, AZ, October 30-November 3
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Isukapalli, S., Wang, S. W., Ozkaynak, H., & Georgopoulos, P. G. (2005). Source-to-dose modeling of long-term population exposures to reactive and non-reactive air pollutants: Indoor and outdoor contributions. Paper presented at The 15th Annual ISEA Conference, Tucson, AZ, October 30-November 3.
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15th Annual ISEA Conference
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Isukapalli, S.1
Wang, S.W.2
Ozkaynak, H.3
Georgopoulos, P.G.4
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0033857052
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Measurement of total lung deposition of inhaled ultrafine particles in healthy men and women
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Jaques, P. A., & Kim, C. S. (2000). Measurement of total lung deposition of inhaled ultrafine particles in healthy men and women. Inhalation Toxicology, 12, 715-731.
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Inhalation Toxicology
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Jaques, P.A.1
Kim, C.S.2
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0003645565
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Richland, WA: National Radiological Protection Board (NRPB-SR287)
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Jarvis, N. S., Birchall, A., James, A. C., Bailey, M. R., & Dorrian, M.-D. (1996). LUDEP 2.0 Personal computer program for calculating internal doses using the ICRP Publication 66 respiratory tract model. Richland, WA: National Radiological Protection Board (NRPB-SR287).
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LUDEP 2.0 Personal Computer Program for Calculating Internal Doses Using the ICRP Publication 66 Respiratory Tract Model
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Jarvis, N.S.1
Birchall, A.2
James, A.C.3
Bailey, M.R.4
Dorrian, M.-D.5
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Gaussian mixture clustering and imputation of microarray data
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Ouyang, M., Welsh, W. J., & Georgopoulos, P. (2004). Gaussian mixture clustering and imputation of microarray data. Bioinformatics, 20, 917-923.
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Bioinformatics
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Welsh, W.J.2
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33750837761
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San Francisco, CA: The Lifeline Group for The Exposure Technical Implementation Panel, American Chemistry Council (Contract Number 1338)
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Price, P. S., Chaisson, C. F., Koontz, M., Wilkes, C., Ryan, B., Macintosh, D., et al. (2003). Construction of a comprehensive chemical exposure framework using person oriented modeling. San Francisco, CA: The Lifeline Group for The Exposure Technical Implementation Panel, American Chemistry Council (Contract Number 1338).
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Construction of a Comprehensive Chemical Exposure Framework Using Person Oriented Modeling
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Price, P.S.1
Chaisson, C.F.2
Koontz, M.3
Wilkes, C.4
Ryan, B.5
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34248171143
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Medicine. Environmental biology and human disease
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Schwartz, D., & Collins, F. (2007). Medicine. Environmental biology and human disease. Science, 316, 695-696.
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Science
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Computational cell biology: Spatiotemporal simulation of cellular events
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Slepchenko, B. M., Schaff, J. C., Carson, J. H., & Loew, L. M. (2002). Computational cell biology: Spatiotemporal simulation of cellular events. Annual Review of Biophysics and Biomolecular Structure, 31, 423-441.
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Annual Review of Biophysics and Biomolecular Structure
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Schaff, J.C.2
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38349128962
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Prepared for USEPA National Exposure Research Laboratory. Dayton, OH: ManTech Environmental Technologies
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Stallings, C., Tippett, J. A., Glen, G., & Smith, L. (2002). CHAD User's guide: Extracting human activity information from CHAD on the PC. Prepared for USEPA National Exposure Research Laboratory. Dayton, OH: ManTech Environmental Technologies.
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CHAD User's Guide: Extracting Human Activity Information from CHAD on the PC
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Stallings, C.1
Tippett, J.A.2
Glen, G.3
Smith, L.4
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34
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33749178755
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Multiscale plume transport from the collapse of the World Trade Center on September 11, 2001
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Stenchikov, G., Lahoti, N., Diner, D. J., Kahn, R., Lioy, P. J., & Georgopoulos, P. G. (2006). Multiscale plume transport from the collapse of the World Trade Center on September 11, 2001. Environmental Fluid Mechanics, 6, 425-450.
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Environmental Fluid Mechanics
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Stenchikov, G.1
Lahoti, N.2
Diner, D.J.3
Kahn, R.4
Lioy, P.J.5
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38349157181
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Strategy for the EuroPhysiome (STEP) Consortium (2006). First STEP Conference. Available at: http://www.biomedtown.org/biomed_town/STEP/Reception/ step-definitions/STEPConference1.
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First STEP Conference
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36
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0141626866
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E-Cell 2: Multi-platform E-Cell simulation system
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Takahashi, K., Ishikawa, N., Sadamoto, Y., Sasamoto, H., Ohta, S., Shiozawa, A., et al. (2003). E-Cell 2: Multi-platform E-Cell simulation system. Bioinformatics, 19, 1727-1729.
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Bioinformatics
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Takahashi, K.1
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Ohta, S.5
Shiozawa, A.6
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38349168564
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ArrayTrack - Supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research
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38349095183
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UK Environment Agency (2003). Environmental genomics - An introduction. Bristol, UK: UK Environment Agency.
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Environmental Genomics - An Introduction
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Characterizing uncertainties in human exposure modeling through the Random Sampling-High Dimensional Model Representation (RS-HDMR) methodology
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Wang, S. W., Georgopoulos, P. G., Li, G., & Rabitz, H. (2005a). Characterizing uncertainties in human exposure modeling through the Random Sampling-High Dimensional Model Representation (RS-HDMR) methodology. International Journal of Risk Assessment and Management, 5, 387-406.
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International Journal of Risk Assessment and Management
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Wang, S.W.1
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38349099138
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Modeling cumulative and aggregate exposures of co-occurring multimedia contaminants in a probabilistic source-to-dose framework
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Paper presented Tucson, AZ, November
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Wang, S. W., Isukapalli, S., Sasso, A., Yang, Y. C., Zartarian, V., Xue, J., et al. (2005b). Modeling cumulative and aggregate exposures of co-occurring multimedia contaminants in a probabilistic source-to-dose framework. Paper presented at The 15th Annual ISEA Conference, Tucson, AZ, November.
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15th Annual ISEA Conference
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Wang, S.W.1
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Sasso, A.3
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Zartarian, V.5
Xue, J.6
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Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base
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Waters, M., Boorman, G., Bushel, P., Cunningham, M., Irwin, R., Merrick, A., et al. (2003). Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base. Environmental Health Perspectives, 111, 811-824.
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Environmental Health Perspectives
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