Interim monitoring of efficacy data is important and appropriate

Journal of Clinical Epidemiology

Volumn 61, Issue 3, 2008, Pages 203-204

  Sydes, Matthew R ^a   Parmar, Mahesh K B ^a  

^a MRC CLINICAL TRIALS UNIT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DECISION MAKING; ETHICS; HUMAN; OUTCOME ASSESSMENT; PATIENT SAFETY; PRACTICE GUIDELINE; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 38349156411     PISSN: 08954356     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jclinepi.2007.08.002     Document Type: Note

References (2)

1. Bassler D., Montori V.M., Briel M., Glasziou P., and Guyatt G. Early stopping of randomised clinical trials for overt efficacy is problematic. J Clin Epidemiol 61 (2008) 241-246
2. Montori V.M., Devereaux P.J., Adhikari N.K., Burns K.E., Eggert C.H., Briel M., et al. Randomized trials stopped early for benefit: a systematic review. J Am Med Assoc 294 (2005) 2203-2209