A localized negative genetic correlation constrains microevolution of coat color in wild sheep

Science

Volumn 319, Issue 5861, 2008, Pages 318-320

  Gratten, J ^a   Wilson, A J ^b   McRae, A F ^c   Beraldi, D ^b   Visscher, P M ^c   Pemberton, J M ^b   Slate, J ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

TYROSINASE RELATED PROTEIN 1;

COLOR MORPH; EVOLUTION; FITNESS; GENETIC ANALYSIS; HERITABILITY; MUTATION; NATURAL SELECTION; PHENOTYPE; POLYMORPHISM; PREDICTION; SHEEP; SKIN; WILD POPULATION;

ALLELE; ARTICLE; BODY SIZE; COLOR; ENVIRONMENTAL FACTOR; FITNESS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC LINKAGE; GENETIC POLYMORPHISM; HERITABILITY; HETEROZYGOTE; MOLECULAR EVOLUTION; MOLECULAR PHYLOGENY; NONHUMAN; PHENOTYPE; PLEIOTROPY; PREDATOR; PRIORITY JOURNAL; QUANTITATIVE GENETICS; SHEEP; STATISTICAL SIGNIFICANCE; WILD ANIMAL;

ANIMALS; ANIMALS, WILD; BIRTH WEIGHT; BODY SIZE; EVOLUTION; FEMALE; GENOTYPE; HAIR COLOR; HETEROZYGOTE; HOMOZYGOTE; LINEAR MODELS; LINKAGE (GENETICS); MALE; OXIDOREDUCTASES; PHENOTYPE; QUANTITATIVE TRAIT LOCI; REPRODUCTION; SCOTLAND; SELECTION (GENETICS); SHEEP;

OVIS ARIES;

EID: 38349153127     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1151182     Document Type: Article

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25. We thank J. Pilkington, project members, and many volunteers for collecting data and genetic samples; J. Hadfield and S. Nakagawa for statistical advice; F. Pelletier for estimates of de-lifed fitness; T. Coulson and L. Kruuk for helpful discussion; the National Trust for Scotland and Scottish Natural Heritage for permission to access St. Kilda; and QinetiQ for logistical support. Comments from anonymous referees improved this manuscript. Funded by the Natural Environment Research Council. The Australian National Health and Medical Research Council provided support to P.M.V. and A.F.M.