Synthesis and structure-activity relationships of metal-ligand complexes that potently inhibit cell migration

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 2, 2008, Pages 498-504

  Beshir, Anwar B ^a   Guchhait, Sankar K ^a   Gascón, José A ^a   Fenteany, Gabriel ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Cell migration inhibitors; Metal ligand complexes; Structure activity relationships

Indexed keywords

2 ACETYLPYRIDINE; COPPER CHLORIDE; COPPER DERIVATIVE; DITHIOCARBAMIC ACID DERIVATIVE; NICKEL; NSC 295642; PYRIDINE DERIVATIVE; S BENZYL DITHIOCARBAZATE; SCHIFF BASE; SOLVENT; UNCLASSIFIED DRUG; WATER; ZINC;

ARTICLE; BREAST CARCINOMA; CANCER CELL; CANCER INHIBITION; CELL MIGRATION; CELL MOTILITY; CELL TYPE; CHELATION; COLORECTAL CARCINOMA; COMPLEX FORMATION; DENSITY FUNCTIONAL THEORY; DRUG SYNTHESIS; ELECTRONIC GROUND STATE GEOMETRY; GENETIC SCREENING; GEOMETRY; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METAL BINDING; NUCLEAR MAGNETIC RESONANCE; PHARMACOPHORE; PROTEIN TARGETING; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VACUUM; WOUND CLOSURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; CELL MOVEMENT; CHELATING AGENTS; CHROMATOGRAPHY, LIQUID; CRYSTALLOGRAPHY, X-RAY; LIGANDS; MASS SPECTROMETRY; METALS; STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA;

EID: 38349151880     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.11.099     Document Type: Article

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