Genetic testing is ready to change the diagnostic scenario of lactose malabsorption [2]

Gut

Volumn 57, Issue 1, 2008, Pages 137-138

  Usai Satta, P ^a   Congia, M ^b   Schirru, E ^b   Scarpa, M ^a   Mura, G ^a  

^a BROTZU HOSPITAL   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LACTOSE;

BREATH ANALYSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FALSE NEGATIVE RESULT; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HUMAN; JEJUNUM BIOPSY; LACTOSE INTOLERANCE; LETTER; PRIORITY JOURNAL; RISK; SMALL INTESTINE MUCOSA;

ADOLESCENT; ADULT; AGED; ALGORITHMS; BREATH TESTS; GENETIC SCREENING; HUMANS; LACTOSE INTOLERANCE; MIDDLE AGED;

EID: 38349149770     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2007.134627     Document Type: Letter

References (6)

1. Rasinpera H, Savilahti E, Enattah NS, et al. A genetic test can be used to diagnose adult-type hypolactasia in children. Gut 2004;53:1571-6.
2. Enattah NS, Sahi T, Savilahti R, et al. Identification of a variant associated with adult-type hypolactasia. Nat Genet 2002;30:233-7.
3. Bodlaj G, Stocher M, Hufnlagl P, et al. Genotyping of the lactase-phlorizin hydrolase-13910 polymorphism by LightCycler PCR and implications for the diagnosis of lactose intolerance. Clin Chem 2006;52:148-51.
4. Schirru E, Corona V, Usai Satta P, et al. Genetic testing improves the diagnosis of adult type hypolactasia in the Mediterranean population of Sardinia. Eur J Clin Nutr 2007; 61:1220-5.
5. Szilagyi A, Malolepszy P, Hamard E, et al. Comparison of a real-time polymerase chain reaction assay for lactase genetic polymorphism with standard indirect test for lactose maldigestion. Clin Gastroenterol Hepatol 2007;5:192-6.
6. Schirru E, Corona V, Usai Satta P, et al. Diagnosis of lactose malabsorption and the C/T-13910 variant upstream the lactase hydrolase gene in Sardinian children. J Pediatr Gastroenterol Nutr 2007, in press.