L-enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase

Journal of the American Chemical Society

Volumn 130, Issue 3, 2008, Pages 842-844

  Rinaldo Matthis, Agnes ^a   Murkin, Andrew S ^a   Ramagopal, Udupi A ^a   Clinch, Keith ^b   Mee, Simon P H ^b   Evans, Gary B ^b   Tyler, Peter C ^b   Furneaux, Richard H ^b   Almo, Steven C ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CALLAGHAN INNOVATION   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

FORODESINE; PURINE NUCLEOSIDE PHOSPHORYLASE;

ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; CELLULAR IMMUNITY; CELLULAR IMMUNODEFICIENCY; COMPLEX FORMATION; DISSOCIATION CONSTANT; ENANTIOMER; ENZYME INHIBITION; GEOMETRY; HUMAN; MOLECULAR INTERACTION; PROTEIN STRUCTURE; STEREOCHEMISTRY; STRUCTURE ANALYSIS; T LYMPHOCYTE; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; PROTEIN CONFORMATION; PURINE NUCLEOSIDES; PURINE-NUCLEOSIDE PHOSPHORYLASE; PYRIMIDINONES; PYRROLIDINES; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 38349138985     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja710733g     Document Type: Article

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