Subungual penetration of dibutyl phthalate in human fingernails

Skin Pharmacology and Physiology

Volumn 21, Issue 1, 2008, Pages 10-14

  Jackson, E M ^a  

^a Jackson Research Associates Inc   (United States)

Author keywords

Dibutyl phthalate; Subungual penetration

Indexed keywords

PHTHALIC ACID DIBUTYL ESTER; PLASTICIZER;

ARTICLE; FINGER NAIL; HUMAN; HUMAN CELL; HUMAN TISSUE; METABOLISM; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; SKIN ABSORPTION; SKIN PENETRATION; TERATOGENICITY;

ADMINISTRATION, TOPICAL; AGED; CADAVER; COSMETICS; DIBUTYL PHTHALATE; HUMANS; MALE; MIDDLE AGED; NAILS; OINTMENTS; PERMEABILITY; TIME FACTORS;

EID: 38349133939     PISSN: 16605527     EISSN: None     Source Type: Journal    
DOI: 10.1159/000109083     Document Type: Article

References (11)

1. CTFA: The International Cosmetic Ingredient Dictionary (INCI), ed 5. Washington, Cosmetic, Toiletry and Fragrance Association, 1993, vol 1, p 204.
2. CTFA: The Cosmetic Ingredient Handbook, ed 2. Washington, Cosmetic, Toiletry and Fragrance Association, 1992, p 110.
3. Cosmetic Ingredient Review Expert Panel: Final report on the safety assessment of dibutyl phthalate, dimethyl phthalate and diethyl phthalate. Int J Toxicol 1985;4:267-303.
4. Cosmetic Ingredient Review Expert Panel: Revised Final Report on the Safety Assessment of Dibutyl Phthalate, Dimethyl Phthalate and Diethyl Phthalate. Annual Review of Cosmetic Ingredient Safety Assessments 2002/2003. Washington, Cosmetic Ingredient Review, 2003, pp 39-50.
5. Franz TJ: Percutaneous absorption: on the relevance of in vitro data. J Invest Dermatol 1975;64:190-195.
6. Franz TJ: The finite dose technique as a valid in vitro model for the study of percutaneous absorption in man; in Simon G, Paster Z, Kingberg M, Kaye M (eds): Skin - Drug Application and Evaluation of Environmental Hazards. Curr Probl Dermatol. Basel, Karger, 1973, vol 7, pp 58-66.
7. Final report, study No DP202-630, conducted for Jackson Research Associates Inc, Sumner: assessment of dibutyl phthalate absorption in vitro through human finger nails. San Diego, DermPharm (a division of DermTech International), October 22, 2002.
8. Results of PubMed Search for Jackson Research Associates Inc, Sumner: dibutyl phthalate reproductive toxicity - PubMed 2000 to July 2005. San Diego, PLUS Information Services, Biomedical Library, University of California.
9. Waldman P: From an ingredient in cosmetics, toys, a safety concern. The Wall Street Journal, October 4, 2005, p 1.
10. Panel finds no proof that phthalates harm infant reproductive systems. Science 2005;310:422.
11. Jackson EM: Analysis of the subungual penetration of 100% dibutyl phthalate (DBP) in human fingernails. Prepared for the Nail Manufacturers' Council, Professional Beauty Association, Scottsdale, October 25, 2002.