Physiopathology of rotavirus diarrhea;Physiopathologie de la diarrhée à rotavirus

Journal de Pediatrie et de Puericulture

Volumn 20, Issue 8, 2007, Pages 330-336

  Lorrot, M ^a   Vasseur, M ^b  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b INSERM   (France)

Author keywords

Diarrhea; Gastroenteritis; Intestinal Cl secretion; NSP4; Physiopathology; Rotavirus

Indexed keywords

CHLORIDE ION; ENTEROTOXIN; GLUCOSE; ROTAVIRUS NONSTRUCTURAL PROTEIN 4; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM ION;

APICAL MEMBRANE; ARTICLE; BRUSH BORDER; CARBOHYDRATE ABSORPTION; CHLORIDE TRANSPORT; DIARRHEA; ENZYME ACTIVITY; HISTOPATHOLOGY; HUMAN; INFANT DISEASE; INTESTINE CELL; INTESTINE VILLUS; MALABSORPTION; ROTAVIRUS; SODIUM TRANSPORT;

EID: 38349132724     PISSN: 09877983     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpp.2007.11.010     Document Type: Article

References (43)

1. Kapikian A.Z., and Chanock R.M. Rotaviruses. In: Fields B.N., Knipe D.M., and Howley P.M. (Eds). Fields virology (1996), Lippincot-Raven, Philadelphia 1657-1708
2. Parashar U.D., Hummelman E.G., Bresee J.S., et al. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis 9 (2003) 565-572
3. Parashar U.D., Gibson C.J., Bresee J.S., et al. Rotavirus and severe childhood diarrhea. Emerg Infect Dis 12 (2006) 304-306
4. Lundgren O., and Svensson L. Pathogenesis of rotavirus diarrhea. Microbes Infect 3 (2001) 1145-1156
5. Blutt S.E., Matson D.O., Crawford S.E., et al. Rotavirus antigenemia in children is associated with viremia. PLoS Med 4 (2007) e121
6. Stephen J. Pathogenesis of infectious diarrhea. Can J Gastroenterol 15 (2001) 669-683
7. Morris A.P., and Estes M.K. Microbes and microbial toxins: paradigms for microbial-mucosal interactions. VIII. Pathological consequences of rotavirus infection and its enterotoxin. Am J Physiol Gastrointest Liver Physiol 281 (2001) G303-G310
8. Ramig R.F. Pathogenesis of intestinal and systemic rotavirus infection. J Virol 78 (2004) 10213-10220
9. Ball J.M., Tian P., Zeng C.Q., Morris A.P., and Estes M.K. Age-dependent diarrhea induced by a rotaviral nonstructural glycoprotein. Science 272 (1996) 101-104
10. 2+ in the replication and pathogenesis of rotavirus and other viral infections. Cell Calcium 28 (2000) 137-149
11. Lopez S., and Arias C.F. Early steps in rotavirus cell entry. Curr Top Microbiol Immunol 309 (2006) 39-66
12. Martin S., Lorrot M., El Azher M.A., et al. Ionic strength- and temperature-induced K (Ca) shifts in the uncoating reaction of rotavirus strains RF and SA11: correlation with membrane permeabilization. J Virol 76 (2002) 552-559
13. Davidson G.P., Gall D.G., Petric M., et al. Human rotavirus enteritis induced in conventional piglets. Intestinal structure and transport. J Clin Invest 60 (1977) 1402-1409
14. Davidson G.P., and Barnes G.L. Structural and functional abnormalities of the small intestine in infants and young children with rotavirus enteritis. Acta Paediatr Scand 68 (1979) 181-186
15. Greenberg H.B., Clark H.F., and Offit P.A. Rotavirus pathology and pathophysiology. Curr Top Microbiol Immunol 185 (1994) 256-283
16. Graham D.Y., Sackman J.W., and Estes M.K. Pathogenesis of rotavirus-induced diarrhea-preliminary studies in miniature smine piglet. Dig Dis Sci 29 (1984) 1028-1035
17. Collins J., Starkey W.G., Wallis T.S., et al. Intestinal enzyme profiles in normal and rotavirus-infected mice. J Pediatr Gastroenterol Nutr 7 (1988) 264-272
18. Collins J., Candy D.C., Starkey W.G., et al. Disaccharidase activities in small intestine of rotavirus-infected suckling mice: a histochemical study. J Pediatr Gastroenterol Nutr 11 (1990) 395-403
19. Jourdan N., Brunet J.P., Sapin C., et al. Rotavirus infection reduces sucrase-isomaltase expression in human intestinal epithelial cells by perturbing protein targeting and organization of microvillar cytoskeleton. J Virol 72 (1998) 7228-7236
20. Martin-Latil S., Cotte-Laffitte J., Beau I., et al. A cyclic AMP protein kinase A-dependent mechanism by which rotavirus impairs the expression and enzyme activity of brush border-associated sucrase-isomaltase in differentiated intestinal Caco-2 cells. Cell Microbiol 6 (2004) 719-731
21. Beau I., Cotte-Laffitte J., Geniteau-Legendre M., et al. An NSP4-dependant mechanism by which rotavirus impairs lactase enzymatic activity in brush border of human enterocyte-like Caco-2 cells. Cell Microbiol 9 (2007) 2254-2266
22. Beau I., Berger A., and Servin A.L. Rotavirus impairs the biosynthesis of brush-border-associated dipeptidyl peptidase IV in human enterocyte-like Caco-2/TC7 cells. Cell Microbiol 9 (2007) 779-789
23. Salim A.F., Phillips A.D., Walker-Smith J.A., et al. Sequential changes in small intestinal structure and function during rotavirus infection in neonatal rats. Gut 36 (1995) 231-238
24. Katyal R., Rana S.V., Vaiphei K., et al. Effect of rotavirus infection on small gut pathophysiology in a mouse model. J Gastroenterol Hepatol 14 (1999) 779-784
25. Halaihel N., Lievin V., Alvarado F., et al. Rotavirus infection impairs intestinal brush-border membrane Na(+) solute cotransport activities in young rabbits. Am J Physiol Gastrointest Liver Physiol 279 (2000) G587-G596
26. Brunet J.P., Cotte-Laffitte J., Linxe C., et al. Rotavirus infection induces an increase in intracellular calcium concentration in human intestinal epithelial cells: role in microvillar actin alteration. J Virol 74 (2000) 2323-2332
27. Tafazoli F., Zeng C.Q., Estes M.K., et al. NSP4 enterotoxin of rotavirus induces paracellular leakage in polarized epithelial cells. J Virol 75 (2001) 1540-1546
28. Obert G., Peiffer I., and Servin A.L. Rotavirus-induced structural and functional alterations in tight junctions of polarized intestinal Caco-2 cell monolayers. J Virol 74 (2000) 4645-4651
29. Dickman K.G., Hempson S.J., Anderson J., et al. Rotavirus alters paracellular permeability and energy metabolism in Caco-2 cells. Am J Physiol Gastrointest Liver Physiol 279 (2000) G757-G766
30. Starkey W.G., Collins J., Candy D.C., et al. Transport of water and electrolytes by rotavirus-infected mouse intestine: a time course study. J Pediatr Gastroenterol Nutr 11 (1990) 254-260
31. Spencer A.J., Osborne M.P., Haddon S.J., et al. X-ray microanalysis of rotavirus-infected mouse intestine: a new concept of diarrheal secretion. J Pediatr Gastroenterol Nutr 10 (1990) 516-529
32. - reabsorption process across the intestinal brush-border membrane of young rabbits. J Virol 77 (2003) 9305-9311
33. Lorrot M., Benhamadouche-Casari H., and Vasseur M. Mechanisms of net chloride secretion during rotavirus diarrhea in young rabbits: do intestinal villi secrete chloride?. Cell Physiol Biochem 18 (2006) 103-112
34. Lorrot M., and Vasseur M. How do the rotavirus NSP4 and bacterial enterotoxins lead differently to diarrhea?. J Virol 21 4 (2007) 31
35. Field M. Intestinal ion transport and the pathophysiology of diarrhea. J Clin Invest 111 (2003) 931-943
36. Michelangeli F., and Ruiz M.C. Physiology and pathophysiology of the gut in relation to viral diarrhea. In: Desselberger U., and Gray J. (Eds). Viral gastroenteritis (2003), Elsevier Science B. V 23-50
37. Dong Y., Zeng C.Q., Ball J.M., et al. The rotavirus enterotoxin NSP4 mobilizes intracellular calcium in human intestinal cells by stimulating phospholipase C-mediated inositol 1,4,5-trisphosphate production. Proc Natl Acad Sci U S A 94 (1997) 3960-3965
38. Zhang M., Zeng C.Q., Morris A.P., et al. A functional NSP4 enterotoxin peptide secreted from rotavirus-infected cells. J Virol 74 (2000) 11663-11670
39. Ciarlet M., and Estes M.K. Interactions between rotavirus and gastrointestinal cells. Curr Opin Microbiol 4 (2001) 435-441
40. Halaihel N., Lievin V., Ball J.M., Estes M.K., Alvarado F., and Vasseur M. Direct inhibitory effect of rotavirus NSP4 (114-135) peptide on the Na(+) d-glucose symporter of rabbit intestinal brush border membrane. J Virol 74 (2000) 9464-9470
41. Kordasti S., Istrate C., Banasaz M., et al. Rotavirus infection is not associated with small intestinal fluid secretion in the adult mouse. J Virol 80 (2006) 11355-11361
42. Lundgren O., Peregrin A.T., Persson K., et al. Role of the enteric nervous system in the fluid and electrolyte secretion of rotavirus diarrhea. Science 21 287 (2000) 491-495
43. Louvard D., Kedinger M., and Hauri H.P. The differentiating intestinal epithelial cell: establishment and maintenance of functions through interactions between cellular structures. Annu Rev Cell Biol 8 (1992) 157-195