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Volumn 38, Issue 2, 2008, Pages 357-364

Glutamine preferentially inhibits T-helper type 2 cell-mediated airway inflammation and late airway hyperresponsiveness through the inhibition of cytosolic phospholipase A2 activity in a murine asthma model

Author keywords

Airway hyperresponsiveness; Asthma; CPLA2; Glutamine; Th2

Indexed keywords

CYTOKINE; G 8540; GLUTAMINE; MESSENGER RNA; MUCIN; PHOSPHOLIPASE A2; UNCLASSIFIED DRUG;

EID: 38349118907     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2007.02900.x     Document Type: Article
Times cited : (27)

References (33)
  • 1
    • 0031627189 scopus 로고    scopus 로고
    • Hepatic Glutamine transport and metabolism
    • Häussinger D. Hepatic Glutamine transport and metabolism. Adv Enzymol 1998 72: 43 86.
    • (1998) Adv Enzymol , vol.72 , pp. 43-86
    • Häussinger, D.1
  • 2
    • 0029977185 scopus 로고    scopus 로고
    • The role of glutamine and other alternate substrates as energy sources in the fetal rat lung type II cell
    • Fox RE, Hopkins IB, Cabacungan ET, Tildon JT. The role of glutamine and other alternate substrates as energy sources in the fetal rat lung type II cell. Pediatr Res 1996 40: 135 41.
    • (1996) Pediatr Res , vol.40 , pp. 135-41
    • Fox, R.E.1    Hopkins, I.B.2    Cabacungan, E.T.3    Tildon, J.T.4
  • 3
    • 0031696827 scopus 로고    scopus 로고
    • Glutamine biosynthesis and the utilization of succinate and glutamine by Rhizobium etli and Sinorhizobium meliloti
    • Encarnacion S, Calderon J, Gelbard AS, Cooper AJ, Mora J. Glutamine biosynthesis and the utilization of succinate and glutamine by Rhizobium etli and Sinorhizobium meliloti. Microbiology 1998 144: 2629 38.
    • (1998) Microbiology , vol.144 , pp. 2629-38
    • Encarnacion, S.1    Calderon, J.2    Gelbard, A.S.3    Cooper, A.J.4    Mora, J.5
  • 4
    • 0020536675 scopus 로고
    • Mitochondrial metabolism of glutamine and glutamate and its physiological significance
    • Kovacevic Z, McGivan JD. Mitochondrial metabolism of glutamine and glutamate and its physiological significance. Physiol Rev 1983 63: 547 605.
    • (1983) Physiol Rev , vol.63 , pp. 547-605
    • Kovacevic, Z.1    McGivan, J.D.2
  • 5
    • 0022196860 scopus 로고
    • Glutamine metabolism in lymphocytes: Its biochemical, physiological, and clinical importance
    • Newsholme EA, Crabtree B, Ardawi MSM. Glutamine metabolism in lymphocytes: its biochemical, physiological, and clinical importance. Q J Exp Physiol 1985 70: 473 89.
    • (1985) Q J Exp Physiol , vol.70 , pp. 473-89
    • Newsholme, E.A.1    Crabtree, B.2    Ardawi, M.S.M.3
  • 6
    • 0035513751 scopus 로고    scopus 로고
    • Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia
    • Wischmeyer PE, Kahana M, Wolfson R, Ren H, Musch MM, Chang EB. Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia. Shock 2001 16: 398 402.
    • (2001) Shock , vol.16 , pp. 398-402
    • Wischmeyer, P.E.1    Kahana, M.2    Wolfson, R.3    Ren, H.4    Musch, M.M.5    Chang, E.B.6
  • 7
    • 0030904577 scopus 로고    scopus 로고
    • Six-month outcome of critically ill patients given glutamine supplemented parenteral nutrition
    • Griffiths RD, Jones C, Palmer TE. Six-month outcome of critically ill patients given glutamine supplemented parenteral nutrition. Nutrition 1997 13: 295 302.
    • (1997) Nutrition , vol.13 , pp. 295-302
    • Griffiths, R.D.1    Jones, C.2    Palmer, T.E.3
  • 9
    • 33646797447 scopus 로고    scopus 로고
    • Glutamine inhibits lipopolysaccharide-induced cytoplasmic phospholipase A2 activation and protects against endotoxin shock in mouse
    • Kim YS, Kim GY, Kim JH et al. Glutamine inhibits lipopolysaccharide- induced cytoplasmic phospholipase A2 activation and protects against endotoxin shock in mouse. Shock 2006 25: 290 4.
    • (2006) Shock , vol.25 , pp. 290-4
    • Kim, Y.S.1    Kim, G.Y.2    Kim, J.H.3
  • 10
    • 0031445523 scopus 로고    scopus 로고
    • 2 in allergic response and parturition
    • 2 in allergic response and parturition. Nature 1997 390: 618 22.
    • (1997) Nature , vol.390 , pp. 618-22
    • Uozumi, N.1    Kume, K.2    Nagase, T.3
  • 13
    • 0029113871 scopus 로고
    • Effect of chronic 5-lipoxygenase inhibition on airway hyperresponsiveness in asthmatic subjects
    • Fischer AR, McFadden CA, Frantz R et al. Effect of chronic 5-lipoxygenase inhibition on airway hyperresponsiveness in asthmatic subjects. Am J Respir Crit Care Med 1995 152: 1203 7.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 1203-7
    • Fischer, A.R.1    McFadden, C.A.2    Frantz, R.3
  • 15
    • 0026874477 scopus 로고
    • Effect of an inhaled thromboxane mimetic (U46619) on airway function in human subjects
    • Jones GL, Saroea HG, Watson RM, O'Byrne PM. Effect of an inhaled thromboxane mimetic (U46619) on airway function in human subjects. Am Rev Respir Dis 1992 145: 1270 4.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 1270-4
    • Jones, G.L.1    Saroea, H.G.2    Watson, R.M.3    O'Byrne, P.M.4
  • 16
    • 0038491280 scopus 로고    scopus 로고
    • Platelet-activating factor-mediated NF-κB-dependency of a late anaphylactic reaction
    • Choi IH, Kim YS, Kim DK et al. Platelet-activating factor-mediated NF-κB-dependency of a late anaphylactic reaction. J Exp Med 2003 198: 145 51.
    • (2003) J Exp Med , vol.198 , pp. 145-51
    • Choi, I.H.1    Kim, Y.S.2    Kim, D.K.3
  • 17
    • 0037214475 scopus 로고    scopus 로고
    • Involvement of the cysteinyl-leukotrienes in allergen-induced airway eosinophilia and hyperresponsiveness in the mouse
    • Eum SY, Maghni K, Hamid Q, Campbell H, Eidelman DH, Martin JG. Involvement of the cysteinyl-leukotrienes in allergen-induced airway eosinophilia and hyperresponsiveness in the mouse. Am J Respir Cell Mol Biol 2003 28: 25 32.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 25-32
    • Eum, S.Y.1    Maghni, K.2    Hamid, Q.3    Campbell, H.4    Eidelman, D.H.5    Martin, J.G.6
  • 18
    • 0030810734 scopus 로고    scopus 로고
    • Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice
    • Takeda K, Hamelmann E, Joetham A et al. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J Exp Med 1997 186: 449 54.
    • (1997) J Exp Med , vol.186 , pp. 449-54
    • Takeda, K.1    Hamelmann, E.2    Joetham, A.3
  • 19
    • 0036229419 scopus 로고    scopus 로고
    • Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency
    • Corry DB, Rishi K, Kanellis J et al. Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency. Nat Immunol 2002 3: 347 53.
    • (2002) Nat Immunol , vol.3 , pp. 347-53
    • Corry, D.B.1    Rishi, K.2    Kanellis, J.3
  • 20
    • 0037111427 scopus 로고    scopus 로고
    • Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy
    • Drouin SM, Corry DB, Hollman TJ, Kildsgaard J, Wetsel RA. Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy. J Immunol 2002 169: 5926.
    • (2002) J Immunol , vol.169 , pp. 5926
    • Drouin, S.M.1    Corry, D.B.2    Hollman, T.J.3    Kildsgaard, J.4    Wetsel, R.A.5
  • 21
    • 0025900437 scopus 로고
    • Asthma and inflammation
    • Kay AB. Asthma and inflammation. J Allergy Clin Immunol 1991 87: 893.
    • (1991) J Allergy Clin Immunol , vol.87 , pp. 893
    • Kay, A.B.1
  • 22
    • 0026026853 scopus 로고
    • Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma
    • Saetta M, Di Stefano A, Rosina C, Thiene G, Fabbri LM. Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma. Am Rev Respir Dis 1991 143: 138.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 138
    • Saetta, M.1    Di Stefano, A.2    Rosina, C.3    Thiene, G.4    Fabbri, L.M.5
  • 24
    • 0032866048 scopus 로고    scopus 로고
    • Montelukast reduces airway eosinophilic inflammation in asthma: A randomized, controlled trial
    • Pizzichini E, Leff JA, Reiss TF et al. Montelukast reduces airway eosinophilic inflammation in asthma: a randomized, controlled trial. Eur Respir J 1999 14: 12 8.
    • (1999) Eur Respir J , vol.14 , pp. 12-8
    • Pizzichini, E.1    Leff, J.A.2    Reiss, T.F.3
  • 25
  • 26
    • 0030835266 scopus 로고    scopus 로고
    • 5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in mice
    • Irvin CG, Tu YP, Sheller JR, Funk CD. 5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in mice. Am J Physiol 1997 272: L1053 8.
    • (1997) Am J Physiol , vol.272
    • Irvin, C.G.1    Tu, Y.P.2    Sheller, J.R.3    Funk, C.D.4
  • 27
    • 10244267521 scopus 로고    scopus 로고
    • The importance of leukotrienes in airway inflammation in a mouse model of asthma
    • Henderson WR, Lewis JDB, Albert RK et al. The importance of leukotrienes in airway inflammation in a mouse model of asthma. J Exp Med 1996 184: 1483 94.
    • (1996) J Exp Med , vol.184 , pp. 1483-94
    • Henderson, W.R.1    Lewis, J.D.B.2    Albert, R.K.3
  • 28
    • 0025150173 scopus 로고
    • Does glutamine contribute to immunosuppression after major burn?
    • Parry-Billings M, Evans J, Calder PC. Does glutamine contribute to immunosuppression after major burn? Lancet 1990 336: 523 5.
    • (1990) Lancet , vol.336 , pp. 523-5
    • Parry-Billings, M.1    Evans, J.2    Calder, P.C.3
  • 29
    • 0027993182 scopus 로고
    • Glutamine kinetics in burn patients comparison with hormonally induced stress in volunteers
    • Gore DC, Jahoor F. Glutamine kinetics in burn patients comparison with hormonally induced stress in volunteers. Arch Surg 1994 129: 1318 23.
    • (1994) Arch Surg , vol.129 , pp. 1318-23
    • Gore, D.C.1    Jahoor, F.2
  • 30
    • 0029890458 scopus 로고    scopus 로고
    • The possible role of glutamine in some cells of the immune system and the possible consequence for the whole animal
    • Newsholme EA. The possible role of glutamine in some cells of the immune system and the possible consequence for the whole animal. Experientia 1996 52: 455 9.
    • (1996) Experientia , vol.52 , pp. 455-9
    • Newsholme, E.A.1
  • 31
    • 0035168102 scopus 로고    scopus 로고
    • Glutamine administration reduces Gram-negative bacteremia in severely burned patients: A prospective, randomized, double-blind trial versus isonitrogenous control
    • Wischmeyer PE, Lynch J, Liedel J et al. Glutamine administration reduces Gram-negative bacteremia in severely burned patients: a prospective, randomized, double-blind trial versus isonitrogenous control. Crit Care Med 2001 29: 2075 80.
    • (2001) Crit Care Med , vol.29 , pp. 2075-80
    • Wischmeyer, P.E.1    Lynch, J.2    Liedel, J.3
  • 32
    • 0027102761 scopus 로고
    • Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. a randomized, double-blind, controlled study
    • Ziegler TR, Young LS, Benfell K et al. Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study. Ann Intern Med 1992 116: 821 8.
    • (1992) Ann Intern Med , vol.116 , pp. 821-8
    • Ziegler, T.R.1    Young, L.S.2    Benfell, K.3
  • 33
    • 0036742213 scopus 로고    scopus 로고
    • Glutamine supplementation in serious illness: A systematic review of the evidence
    • Novak F, Heyland DK, Avenell A, Drover JW, Su X. Glutamine supplementation in serious illness: a systematic review of the evidence. Crit Care Med 2002 30: 2022 9.
    • (2002) Crit Care Med , vol.30 , pp. 2022-9
    • Novak, F.1    Heyland, D.K.2    Avenell, A.3    Drover, J.W.4    Su, X.5


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