Synthesis of enantiomerically enriched (R)-5-tert-butylazepan-2-one using a hydroxyalkyl azide mediated ring-expansion reaction

Nature Protocols

Volumn 3, Issue 1, 2008, Pages 137-143

  Ribelin, Timothy P ^a   Aubé, Jeffrey ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 PHENYL 3 AZIDOPROPANOL; 3 AZIDO 1 PHENYLPROPAN 1 OL; 5 TERT BUTYL 1 (3 HYDROXY 3 PHENYLPROPYL)AZEPAN 2 ONE; 5 TERT BUTYL 1 (3 OXO 3 PHENYLPROPYL)AZEPAN 2 ONE; 5 TERT BUTYLAZEPAN 2 ONE; AZIDE; AZIDO 1 PHENYLPROPANOL; CAPROLACTAM; HYDROXYALKYLAZIDE; KETONE DERIVATIVE; LEWIS ACID; PROPANOL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHIRALITY; CRYSTALLIZATION; DENITRIFICATION; ENANTIOMER; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RELIABILITY; RING EXPANSION REACTION; STEREOCHEMISTRY;

AZEPINES; AZIDES; CHEMISTRY, ORGANIC; STEREOISOMERISM;

EID: 38349117502     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2007.518     Document Type: Article

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