In vitro and in vivo effects of endothelin-1 and YM598, a selective endothelin ETA receptor antagonist, on the lower urinary tract

European Journal of Pharmacology

Volumn 580, Issue 3, 2008, Pages 394-400

  Ukai, Masashi ^a   Yuyama, Hironori ^a   Fujimori, Akira ^a   Koakutsu, Akiko ^a   Sanagi, Masanao ^a   Ohtake, Akiyoshi ^a   Sato, Shuichi ^a   Sudoh, Katsumi ^a   Sasamata, Masao ^a   Miyata, Keiji ^a  

^a Applied Pharmacology II   (Japan)

Author keywords

(Dog); (Rabbit); Antagonist; Endothelin ETA receptor; Endothelin 1; Lower urinary tract; Urethral pressure; YM598

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; N [6 METHOXY 5 (2 METHOXYPHENOXY)(2, 2 BIPYRIMIDIN) 4YL] 2 PHENYLETHENESULFONAMIDE MONOPOTASSIUM SALT; TAMSULOSIN; UNCLASSIFIED DRUG; YM 598;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER; CONTROLLED STUDY; DOG; DRUG DOSE ESCALATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL; PROSTATE; PROSTATE HYPERTROPHY; RABBIT; URETHRA; URETHRA PRESSURE;

ACETYLCHOLINE; ANIMALS; BLOOD PRESSURE; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENDOTHELIN-1; HEART RATE; INJECTIONS, INTRA-ARTERIAL; INJECTIONS, INTRAVENOUS; MALE; MOLECULAR STRUCTURE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PHENYLEPHRINE; PROSTATE; PYRIMIDINES; RABBITS; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; SULFONAMIDES; URETHRA; URINARY BLADDER; VIPER VENOMS;

EID: 38349101933     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.11.021     Document Type: Article

References (22)

1. Arai H., Hori S., Aramori I., Ohkubo H., and Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature 348 (1990) 730-732
2. Caine M., Raz S., and Zeigler M. Adrenergic and cholinergic receptors in the human prostate, prostatic capsule and bladder neck. Br. J. Urol. 47 (1975) 193-202
3. Henry P.J., Rigby P.J., Self G.J., Preuss J.M., and Goldie R.G. Relationship between endothelin-1 binding site densities and constrictor activities in human and animal airway smooth muscle. Br. J. Pharmacol. 100 (1990) 786-792
4. Higashi T., Ishizaki T., Shigemori K., Yamamura T., and Nakai T. Pharmacological characterization of endothelin-induced rat pulmonary arterial dilatation. Br. J. Pharmacol. 121 (1997) 782-786
5. Honda K., Miyata-Osawa A., and Takenaka T. alpha 1-Adrenoceptor subtype mediating contraction of the smooth muscle in the lower urinary tract and prostate of rabbits. Naunyn-Schmiedebergs Arch. Pharmacol. 330 (1985) 16-21
6. Inoue A., Yanagisawa M., Kimura S., Kasuya Y., Miyauchi T., Goto K., and Masaki T. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc. Natl. Acad. Sci. U. S. A. 86 (1989) 2863-2867
7. Imajo C., Walden P.D., Shapiro E., Doherty A.M., and Lepor H. Evaluation of the effect of endothelin-1 and characterization of the selective endothelin a receptor antagonist PD155080 in the prostate. J. Urol. 158 (1997) 253-257
8. Kobayashi S., Tang R., Wang B., Opgenorth T., Stein E., Shapiro E., and Lepor H. Localization of endothelin receptors in the human prostate. J. Urol. 151 (1994) 763-766
9. Kondo S., Morita T., and Tashima Y. Benign prostatic hypertrophy affects the endothelin receptor density in the human urinary bladder and prostate. Urol. Int. 54 (1995) 198-203
10. Langenstroer P., Tang R., Shapiro E., Divish B., Opgenorth T., and Lepor H. Endothelin-1 in the human prostate: tissue levels, source of production and isometric tension studies. J. Urol. 150 (1993) 495-499
11. Langenstroer P., Tang R., Divish B., Opgenorth T., Shapiro E., and Lepor H. Endothelins in canine genitourinary tissues. J. Urol. 157 (1997) 1044-1048
12. Latifpour J., Fukumoto Y., and Weiss R.M. Regional differences in the density and subtype specificity of endothelin receptors in rabbit urinary tract. Naunyn-Schmiedebergs Arch. Pharmacol. 352 (1995) 459-468
13. Maggi C.A., Giuliani S., Patacchini R., Santicioli P., Turini D., Barbanti G., and Meli A. Potent contractile activity of endothelin on the human isolated urinary bladder. Br. J. Pharmacol. 96 (1989) 755-757
14. Mumtaz F.H., Dashwood M.R., Thompson C.S., Sullivan M.E., Mikhailidis D.P., and Morgan R.J. Increased expression of endothelin B receptors in the diabetic rabbit urinary bladder: functional relevance. BJU. Int. 83 (1999) 113-122
15. Normandin D.E., and Lodge N.J. Pharmacological characterization of the isolated canine prostate. J. Urol. 155 (1996) 1758-1761
16. Sakurai T., Yanagisawa M., Takuwa Y., Miyazaki H., Kimura S., Goto K., and Masaki T. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 348 (1990) 732-735
17. Salamoussa A., Lau W.A., Pennefather J.N., and Ventura S. The contractile effects of endothelins on the smooth muscle of the rat prostate gland. Eur. J. Pharmacol. 403 (2000) 139-145
18. Sudoh K., Tanaka H., Inagaki O., Asano M., and Takenaka T. Effect of tamsulosin, a novel alpha 1-adrenoceptor antagonist, on urethral pressure profile in anaesthetized dogs. J. Auton. Pharmacol. 16 (1996) 147-154
19. Wada Y., Latifpour J., Sanematsu H., Afiatpour P., Wang Z., Saito M., Nishi K., and Weiss R.M. Age-related changes in contractile responses of rabbit lower urinary tract to endothelin. J. Urol. 164 (2000) 806-813
20. Yanagisawa M., Kurihara H., Kimura S., Tomobe Y., Kobayashi M., Mitsui Y., Yazaki Y., Goto K., and Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332 (1988) 411-415
21. A receptor antagonist. Eur. J. Pharmacol. 478 (2003) 61-71
22. A receptor antagonist. Eur. J. Pharmacol. 498 (2004) 171-177