Multicenter study on in vitro characterization of dendritic cells

Cytotherapy

Volumn 10, Issue 1, 2008, Pages 21-29

  Eichler, H ^a   Nguyen, X D ^a   Roelen, D ^b   Celluzzi, C M ^c   McKenna, D ^d   Pamphilon, D ^e   Blair, A ^e   Read, E J ^f   Takahashi, T A ^g   Szczepiorkowski, Z M ^h  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF MARYLAND   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

^e NHS BLOOD AND TRANSPLANT   (United Kingdom)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

^g THE UNIVERSITY OF TOKYO   (Japan)

^h DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

Assay standardization; Dendritic cells; Good manufacturing practice; Product characterization; Quality control; Vaccines

Indexed keywords

CD14 ANTIGEN; CD16 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; DENDRITIC CELL VACCINE; HLA DR ANTIGEN; T6 ANTIGEN;

ADULT; ARTICLE; CANCER IMMUNOTHERAPY; CELL COUNT; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; CRYOPRESERVATION; FLOW CYTOMETRY; FREEZE THAWING; GOOD MANUFACTURING PRACTICE; HUMAN; IMMUNOPHENOTYPING; IN VITRO STUDY; MALE; MONOCYTE; PILOT STUDY; PRIORITY JOURNAL; QUALITY CONTROL; STANDARDIZATION; VOLUNTEER;

EID: 38349098694     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1080/14653240701744263     Document Type: Article

References (19)

1. Steinman, RM and Hemmi, H. (2006) Dendritic cells: Translating innate to adaptive immunity. Curr Top Microbiol Immunol, 311, pp. 17-58.
2. Schuler, G., Schuler-Thurner, B. and Steinman, RM. (2003) The use of dendritic cells in cancer immunotherapy. Curr Opin Immunol, 15, pp. 138-147.
3. Dhodapkar, MV, Steinman, RM and Sapp, M. (1999) Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells. J Clin Invest, 104, pp. 173-180.
4. Gilboa, E., Nair, SK and Lyerly, HK. (1998) Immunotherapy of cancer with dendritic cell-based vaccines. Cancer Immunol Immunother, 46, pp. 82-87.
5. Schadendorf, D. and Nestle, FO. (2001) Autologous dendritic cells for treatment of advanced cancer: An update. Recent Results Cancer Res, 158, pp. 236-248.
6. Schuler, G., Schuler-Thurner, B. and Steinman, RM. (2003) The use of dendritic cells in cancer immunotherapy. Curr Opin Immunol, 15, pp. 138-147.
7. Ardavin, C., Amigorena, S., Reis, C. and Sousa, e. (2004) Dendritic cells: Immunobiology and cancer immunotherapy. Immunity, 20, pp. 17-23.
8. Schadendorf, D., Ugurel, S. and Schuler-Thurner, B. (2006) Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: A randomized phase III trial of the DC study group of the DeCOG. Ann Oncol, 17, pp. 563-570.
9. Schendel, DJ. (2007) Dendritic cell vaccine strategies for renal cell carcinoma. Expert Opin Biol Ther, 7, pp. 221-232.
10. Kyte, JA and Gaudernack, G. (2006) Immuno-gene therapy of cancer with tumour-mRNA transfected dendritic cells. Cancer Immunol Immunother, 55, pp. 1432-1442.
11. Li, L., Giannopoulos, K. and Reinhardt, P. (2006) Immunotherapy for patients with acute myeloid leukemia using autologous dendritic cells generated from leukemic blasts. Int J Oncol, 28, pp. 855-861.
12. Garderet, L., Cao, H. and Salamero, J. (2001) In vitro production of dendritic cells from human blood monocytes for therapeutic use. J Hematother Stem Cell Res, 4, pp. 553-567.
13. + monocytes to generate dendritic cells for cancer immunotherapy: A phase I study. J Hematother Stem Cell Res, 12, pp. 515-523.
14. + monocytes for anti-tumor immunotherapy. Leuk Lymphoma, 45, pp. 1419-1428.
15. Nguyen, XD, Eichler, H. and Sucker, A. (2002) Collection of autologous monocytes for dendritic cell vaccination therapy in metastatic melanoma patients. Transfusion, 42, pp. 428-432.
16. Figdor, CG, de Vries, IJ and Lesterhuis, WJ (2004) Dendritic cell immunotherapy: Mapping the way. Nature Med, 10, pp. 475-480.
17. de Vries, IJ, Eggert, AA and Scharenborg, NM (2002) Phenotypical and functional characterization of clinical grade dendritic cells. J Immunother, 25, pp. 429-438.
18. Moroff, G., Eichler, H. and Brand, A. (2006) Multiple-laboratory comparison of in vitro assays utilized to characterize hematopoietic cells in cord blood. Transfusion, 46, pp. 507-515.
19. Westermann, J., Korner, IJ and Kopp, J. (2003) Cryopreservation of mature monocyte-derived human dendritic cells for vaccination: Influence on phenotype and functional properties. Cancer Immunol Immunother, 52, pp. 194-198.