Steroid-responsive chronic cerebellitis with positive glutamate receptor δ2 antibody

Journal of Child Neurology

Volumn 23, Issue 2, 2008, Pages 228-230

  Kubota, Masaya ^a   Takahashi, Yukitoshi ^a  

^a Tokyo Metropolitan Hachioji Children's Hospital   (Japan)

Author keywords

Chronic cerebellitis; Glutamate receptor 2

Indexed keywords

CORTICOSTEROID; DIPHTHERIA PERTUSSIS TETANUS VACCINE; GLUCOSE; GLUTAMATE RECEPTOR DELTA2 ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; METHYLPREDNISOLONE; PREDNISOLONE; RECEPTOR ANTIBODY; STEROID; UNCLASSIFIED DRUG;

ARTICLE; CASE REPORT; CEREBELLAR ATAXIA; CEREBELLUM DISEASE; CEREBROSPINAL FLUID ANALYSIS; CHRONIC CEREBELLITIS; DISEASE COURSE; DRUG DOSE REDUCTION; DRUG DOSE REGIMEN; DRUG MEGADOSE; FEMALE; HUMAN; HYPERSALIVATION; KOREA; LYMPHOCYTE COUNT; NYSTAGMUS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN FUNCTION; SYMPTOM; TREATMENT DURATION;

ADRENAL CORTEX HORMONES; AUTOANTIBODIES; CEREBELLAR ATAXIA; CEREBELLAR DISEASES; CHILD, PRESCHOOL; CHRONIC DISEASE; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; METHYLPREDNISOLONE; RECEPTORS, GLUTAMATE; TREATMENT OUTCOME;

EID: 38349096793     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/0883073807307973     Document Type: Article

References (10)

1. Araki K., Meguro H., Kushiya E., et al. Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells. Biochem Biophys Res Commun. 1993;197:1267-1276.
2. Kashiwabuchi N., Ikeda K., Araki K., et al. Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR δ2 mutant mice. Cell. 1995;81:245-252.
3. Funabiki K., Mishina M., Hirano T. Retarded vestibular compensation in mutant mice deficient in δ2 glutamate receptor subunit. Neuroreport. 1995;7:189-192.
4. Kurihara H., Hashimoto K., Kano M., et al. Impaired parallel fiber-Purkinje cell synapse stabilization during cerebellar development of mutant mice lacking the glutamate receptor δ2 subunit. J Neurosci. 1997;17:9613-9623.
5. Kishimoto Y., Kawahara S., Suzuki M., et al. Classical eyeblink conditioning in glutamate receptor subunit δ2 mutant mice is impaired in the delay paradigm but not in the trace paradigm. Eur J Neurosci. 2001;13:1249-1253.
6. Hirai H., Launey T., Mikawa S., et al. New role of delta2-glutamate receptors in AMPA receptor trafficking and cerebellar function. Nat Neurosci. 2003;6:869-876.
7. Takahashi Y., Nishimura S., Sakaguti N., et al. Autoantibodies against GluRδ2 in patients with opsoclonus-Myoclonus syndrome. Neuroimmunology. 2003;11:78.
8. Sugiyama N., Hamano S., Mochizuki M., et al. A case of chronic cerebellitis with anti-glutamate receptor delta 2 antibody. No To Hattatsu. 2004;36:60-63.
9. Ito M. The Cerebellum and Neural Control. New York, NY: Raven: 1984.
10. Ito M. Mechanisms of motor learning in the cerebellum. Brain Res. 2000;886:237-245.