Effect of propylene glycol on ibuprofen absorption into human skin in vivo

Journal of Pharmaceutical Sciences

Volumn 97, Issue 1, 2008, Pages 185-197

  Herkenne, Christophe ^a,b   Naik, Aarti ^a,b   Kalia, Yogeshvar N ^a,b   Hadgraft, Jonathan ^c   Guy, Richard H ^a,d  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Parc d'Affaires International   (France)

^c UNIVERSITY OF LONDON   (United Kingdom)

^d University of Bath   (United Kingdom)

Author keywords

Dermatopharmacokinetics; Diffusivity; Partition coefficient; Percutaneous absorption; Skin; Solubility; Topical drug bioavailability

Indexed keywords

IBUPROFEN; MYRISTIC ACID ISOPROPYL ESTER; PROPYLENE GLYCOL;

ADULT; ANALYSIS OF VARIANCE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG FORMULATION; DRUG SOLUBILITY; DRUG UPTAKE; FEMALE; HUMAN; HUMAN EXPERIMENT; HYDROPHOBICITY; IN VIVO STUDY; MALE; SKIN; STRATUM CORNEUM; THERMODYNAMICS;

EID: 38349093694     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20829     Document Type: Article

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