Pharmacokinetics of polymyxin B1 in patients with multidrug-resistant Gram-negative bacterial infections

Diagnostic Microbiology and Infectious Disease

Volumn 60, Issue 2, 2008, Pages 163-167

  Kwa, Andrea L H ^a   Lim, Tze Peng ^a   Low, Jenny G H ^a   Hou, JingGuo ^b   Kurup, Asok ^a   Prince, Randall A ^b   Tam, Vincent H ^b  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

^b UNIVERSITY OF HOUSTON   (United States)

Author keywords

Multidrug resistant infections; Pharmacokinetics; Polymyxin B

Indexed keywords

POLYMYXIN DERIVATIVE;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; FEMALE; GRAM NEGATIVE INFECTION; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MULTIDRUG RESISTANCE; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; CHROMATOGRAPHY, LIQUID; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; GRAM-NEGATIVE AEROBIC BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HALF-LIFE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; POLYMYXINS; SERUM; TIME FACTORS;

EID: 38349091085     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2007.08.008     Document Type: Article

References (13)

1. ATS/IDSA. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am. J. Respir. Crit. Care Med. 171 (2005) 388-416
2. Evans M.E., Feola D.J., and Rapp R.P. Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant gram-negative bacteria. Ann. Pharmacother. 33 (1999) 960-967
3. Falagas M.E., and Kasiakou S.K. Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections. Clin. Infect. Dis. 40 (2005) 1333-1341
4. Landman D., Bratu S., Alam M., and Quale J. Citywide emergence of Pseudomonas aeruginosa strains with reduced susceptibility to polymyxin B. J. Antimicrob. Chemother. 55 (2005) 954-957
5. Leary R., Jelliffe R., Schumitzky A., and Van Guilder M. An adaptive grid non-parametric approach to pharmacokinetic and dynamic (PK/PD) models. 14th IEEE Symposium on Computer-Based Medical Systems (2001), IEEE Computer Society, Bethesda, MD 289-394
6. Levin A.S., Barone A.A., Penco J., Santos M.V., Marinho I.S., Arruda E.A., Manrique E.I., and Costa S.F. Intravenous colistin as therapy for nosocomial infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. Clin. Infect. Dis. 28 (1999) 1008-1011
7. Li J., Milne R.W., Nation R.L., Turnidge J.D., Coulthard K., and Valentine J. Simple method for assaying colistin methanesulfonate in plasma and urine using high-performance liquid chromatography. Antimicrob. Agents Chemother. 46 (2002) 3304-3307
8. Li J., Coulthard K., Milne R., Nation R.L., Conway S., Peckham D., Etherington C., and Turnidge J. Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosis. J. Antimicrob. Chemother. 52 (2003) 987-992
9. Li J., Milne R.W., Nation R.L., Turnidge J.D., and Coulthard K. Stability of colistin and colistin methanesulfonate in aqueous media and plasma as determined by high-performance liquid chromatography. Antimicrob. Agents Chemother. 47 (2003) 1364-1370
10. Orwa J.A., Van Gerven A., Roets E., and Hoogmartens J. Liquid chromatography of polymyxin B sulphate. J. Chromatogr. A. 870 (2000) 237-243
11. Ouderkirk J.P., Nord J.A., Turett G.S., and Kislak J.W. Polymyxin B nephrotoxicity and efficacy against nosocomial infections caused by multiresistant gram-negative bacteria. Antimicrob. Agents Chemother. 47 (2003) 2659-2662
12. Tam V.H., Louie A., Lomaestro B.M., and Drusano G.L. Integration of population pharmacokinetics, a pharmacodynamic target, and microbiologic surveillance data to generate a rational empiric dosing strategy for cefepime against Pseudomonas aeruginosa. Pharmacotherapy 23 (2003) 291-295
13. Tam V.H., Schilling A.N., Vo G., Kabbara S., Kwa A.L., Wiederhold N.P., and Lewis R.E. Pharmacodynamics of polymyxin B against Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 49 (2005) 3624-3630