Prophylactic antibiotics for the prevention of postpartum infectious morbidity in women infected with human immunodeficiency virus: a randomized controlled trial

American Journal of Obstetrics and Gynecology

Volumn 198, Issue 2, 2008, Pages 189.e1-189.e6

  Sebitloane, H M ^a   Moodley, J ^a   Esterhuizen, T M ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

HIV infected women; postpartum infectious morbidity; prophylactic antibiotics

Indexed keywords

ANTIRETROVIRUS AGENT; CEFOXITIN; NEVIRAPINE; PLACEBO;

ADULT; ANALYTICAL PARAMETERS; ANTIBIOTIC PROPHYLAXIS; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ENDOMETRITIS; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION PREVENTION; INFECTION RATE; INTRAPARTUM CARE; MAJOR CLINICAL STUDY; MORBIDITY; PRIORITY JOURNAL; PUERPERAL INFECTION; PUERPERIUM; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RISK REDUCTION; SEPSIS; SINGLE DRUG DOSE; SOUTH AFRICA; VAGINAL DELIVERY;

EID: 38349090862     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2007.08.053     Document Type: Article

References (18)

1. World Health Organization. The World Health Report 2005: make every mother and child count. Last accessed: December 9, 2005. http://www.who.int/whr/2005.en/index.html
2. Department of Health. National HIV and syphilis antenatal seroprevalence survey in South Africa 2004 (2005), Department of Health, Pretoria, South Africa
3. Saving mothers: third report on confidential enquiries into maternal deaths in South Africa, 2002-2004 (2006), Department of Health, Pretoria, South Africa
4. Le Coeur S., Khlat M., Halembokaka G., et al. HIV and the magnitude of pregnancy-related mortality in Pointe Noire, Congo. AIDS 19 (2005) 69-75
5. Sewankambo N.K., Gray R.H., Ahmad S., et al. Mortality associated with HIV infection in rural Rakai district, Uganda. AIDS 14 (2000) 2391-2400
6. Ahmed Y., Mwaba P., Chintu C., Grange J.M., Ustianowski A., and Zumla A. A study of maternal mortality at the university teaching Hospital, Lusaka, Zambia: the emergence of tuberculosis as a major non-obstetric cause of maternal death. Int J Tuberc Lung Dis 3 (1999) 675-680
7. Smaill F., and Hofmeyr G.J. Antibiotic prophylaxis for cesarean section. Cochrane Database Syst Rev 3 (2002) CD000933
8. Liabsuetrakul T., Choobun T., Peeyananjarassri K., and Islam M. Antibiotic prophylaxis for operative vaginal delivery. Cochrane Database Syst Rev 3 (2004) CD004455
9. Fernandez H., Gagnepain A., Bourget P., et al. Antibiotic prophylaxis against postpartum endometritis after vaginal delivery: a prospective randomized comparison between Amox-CA (Augmentin) and abstention. Eur J Obstet Gynaecol 50 (1993) 169-175
10. Kampikaho A., and Irwig L.M. A randomized trial of penicillin and streptomycin in the prevention of post-partum infection in Uganda. Int J Gynecol Obstet 41 (1993) 43-52
11. Read J.S., Tuomala R., Kpamegan E., et al., Women and Infants Transmission study group. Mode of delivery and postpartum morbidity among HIV-infected women: The women and infants transmission study. J Acquir Immune Defic Syndr 26 (2001) 236-245
12. Urbani G., de Vries M., Cronje H., Niemand I., Bam R., and Beyer E. Complications associated with cesarean section in HIV-infected patients. Int J Gynaecol Obstet 74 (2001) 9-15
13. Burrows L.J., Meyn L.A., and Weber A.M. Maternal morbidity associated with vaginal versus cesarean delivery. Obstet Gynecol 105 (2004) 907-912
14. 4 lymphocytes of < or = 500/microL. Am J Obstet Gynecol 183 (2000) 100-107
15. Hulton L.J., Olmsted R.N., Treston-Aurand J., and Craig C. Effect of postdischarge surveillance on rates of infectious complications after cesarean section. Am J Infect Control 20 (1992) 198-201
16. Tran S.H., Shaffer B.L., Cheng Y.W., Aziz N., Thiet M., and Caughey A.B. Length of rupture of membranes at term and infectious maternal outcomes. Am J Obstet Gynecol 193 suppl 6 (2006) S194
17. Risk factors for mother-to-child transmission of HIV-1: European collaborative study. Lancet 339 (1992) 1007-1012
18. European HIV in Obstetric Group. Higher rates of post-partum complications in HIV-infected than in uninfected women irrespective of mode of delivery. AIDS 18 (2004) 933-938