Anti-inflammatory effects of HO-1 activity in vascular endothelial cells, commentary on "Carbon monoxide donors or heme oxygenase (HO-1) overexpression blocks interleukin-18-mediated NF-κB-PTEN-dependent human cardiac endothelial cell death"

Free Radical Biology and Medicine

Volumn 44, Issue 3, 2008, Pages 261-263

  Tranter, Michael ^a   Jones, W Keith ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CARBON MONOXIDE; CARBON MONOXIDE RELEASING MOLECULE; HEME ARGINATE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 18; INTERLEUKIN 18 ANTIBODY; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 14; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; REACTIVE OXYGEN METABOLITE; SCAVENGER; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL DEATH; CYTOKINE PRODUCTION; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE OVEREXPRESSION; HEART INFARCTION; HEART INJURY; HUMAN; INFLAMMATION; ISCHEMIA; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PATHOLOGY; PNEUMONIA; PRIORITY JOURNAL; PROTEIN FUNCTION; REPERFUSION INJURY; RNA STABILITY; VASCULAR ENDOTHELIUM;

EID: 38349075211     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.10.051     Document Type: Note

References (15)

1. Zabalgoitia M., Colston J.T., Reddy J.V., Holt J.W., Regan R.F., Stec D.E., Rimoldi J.M., Valente A.J., and Chandrasekar B. Carbon monoxide donors or heme oxygenase (HO-1) overexpression blocks interleukin-18-mediated NF-κB-PTEN-dependent human cardiac endothelial cell death. Free Radic. Biol. Med. 44 (2008) 284-298
2. Takahashi T., Morita K., Akagi R., and Sassa S. Heme oxygenase-1: a novel therapeutic target in oxidative tissue injuries. Curr. Med. Chem. 11 (2004) 1545-1561
3. Mannaioni P.F., Vannacci A., and Masini E. Carbon monoxide: the bad and the good side of the coin, from neuronal death to anti-inflammatory activity. Inflamm. Res. 55 (2006) 261-273
4. Motterlini R., Clark J.E., Foresti R., Sarathchandra P., Mann B.E., and Green C.J. Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities. Circ. Res. 90 (2002) E17-E24
5. Vannacci A., Giannini L., Fabrizi F., Uliva C., Mastroianni R., Masini E., Motterlini R., and Mannaioni P.F. Effects of the carbon monoxide releasing molecule CORM-3 in a coincubation model of rat mast cells with human neutrophils. Inflamm. Res. 56 Suppl 1 (2007) S13-S14
6. Pae H.O., Oh G.S., Choi B.M., Chae S.C., Kim Y.M., Chung K.R., and Chung H.T. Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production. J. Immunol. 172 (2004) 4744-4751
7. Freitas A., Alves-Filho J.C., Secco D.D., Neto A.F., Ferreira S.H., Barja-Fidalgo C., and Cunha F.Q. Heme oxygenase/carbon monoxide-biliverdin pathway down regulates neutrophil rolling, adhesion and migration in acute inflammation. Br. J. Pharmacol. 149 (2006) 345-354
8. Chandrasekar B., Valente A.J., Freeman G.L., Mahimainathan L., and Mummidi S. Interleukin-18 induces human cardiac endothelial cell death via a novel signaling pathway involving NF-kappaB-dependent PTEN activation. Biochem. Biophys. Res. Commun. 339 (2006) 956-963
9. Song G., Ouyang G., and Bao S. The activation of Akt/PKB signaling pathway and cell survival. J. Cell. Mol. Med. 9 (2005) 59-71
10. Brouard S., Berberat P.O., Tobiasch E., Seldon M.P., Bach F.H., and Soares M.P. Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis. J. Biol. Chem. 277 (2002) 17950-17961
11. Jones W.K., Brown M., Wilhide M., He S., and Ren X. NF-kappaB in cardiovascular disease: diverse and specific effects of a "general" transcription factor?. Cardiovasc. Toxicol. 5 (2005) 183-202
12. Ishikawa K., Sugawara D., Wang X., Suzuki K., Itabe H., Maruyama Y., and Lusis A.J. Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice. Circ. Res. 88 (2001) 506-512
13. Nakao A., Neto J.S., Kanno S., Stolz D.B., Kimizuka K., Liu F., Bach F.H., Billiar T.R., Choi A.M., Otterbein L.E., and Murase N. Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Am. J. Transplant. 5 (2005) 282-291
14. Tang Y.L., Qian K., Zhang Y.C., Shen L., and Phillips M.I. A vigilant, hypoxia-regulated heme oxygenase-1 gene vector in the heart limits cardiac injury after ischemia-reperfusion in vivo. J. Cardiovasc. Pharmacol. Ther. 10 (2005) 251-263
15. Platt J.L., and Nath K.A. Heme oxygenase: protective gene or Trojan horse. Nat. Med. 4 (1998) 1364-1365