Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes

Cancer Letters

Volumn 260, Issue 1-2, 2008, Pages 163-169

  Yamaguchi, Hiroaki ^a,b   Kobayashi, Minako ^b   Okada, Masahiro ^b   Takeuchi, Toshiko ^b   Unno, Michiaki ^c   Abe, Takaaki ^c,d   Goto, Junichi ^a,b   Hishinuma, Takanori ^b   Mano, Nariyasu ^a,b  

^a TOHOKU UNIVERSITY HOSPITAL   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Antineoplastic drugs; Fluorescent substrate; Imaging; OATP1B3; Rapid screening

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTINEOPLASTIC AGENT; BROMSULFOPHTHALEIN; CAMPTOTHECIN; CARBOPLATIN; CLADRIBINE; CYCLOSPORIN A; CYTARABINE; DACTINOMYCIN; DIGOXIN; DOCETAXEL; ESTRONE SULFATE; FLUOROURACIL; GEMCITABINE; IRINOTECAN; LIOTHYRONINE; LYSINE DERIVATIVE; MERCAPTOPURINE; METHOTREXATE; MITOMYCIN C DERIVATIVE; MITOXANTRONE; ORGANIC ANION TRANSPORTER 1; PACLITAXEL; TAUROCHENODEOXYCHOLIC ACID; THYROXINE; VINBLASTINE; VINCRISTINE;

ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CELL STRAIN HEK293; CONTROLLED STUDY; DIGESTIVE SYSTEM TUMOR; DRUG EFFECT; DRUG SCREENING; FLUORESCENCE; HUMAN; HUMAN CELL; IMAGE ANALYSIS; PRIORITY JOURNAL; SOLID TUMOR;

ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CHENODEOXYCHOLIC ACID; DACTINOMYCIN; FLUORESCENT DYES; HUMANS; KINETICS; LYSINE; MITOXANTRONE; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; PACLITAXEL; SIGNAL PROCESSING, COMPUTER-ASSISTED; SPECTROMETRY, FLUORESCENCE; TAXOIDS; TRANSFECTION;

EID: 38349059946     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2007.10.040     Document Type: Article

References (13)

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