Chlorocyclinones A-D, chlorinated angucyclinones from Streptomyces sp. strongly antagonizing rosiglitazone-induced PPAR-γ activation

Journal of Natural Products

Volumn 70, Issue 12, 2007, Pages 1934-1938

  Potterat, Olivier ^a,c   Puder, Carsten ^a   Wagner, Klaus ^a   Bolek, Walter ^a   Vettermann, Regine ^b,d   Kauschke, Stefan G ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b CyBio Screening GmbH   (Germany)

^c UNIVERSITY OF BASEL   (Switzerland)

^d Wacker Biotech GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGUCYCLINE DERIVATIVE; CHLOROCYCLINONE A; CHLOROCYCLINONE B; CHLOROCYCLINONE C; CHLOROCYCLINONE D; NATURAL PRODUCT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CHLORINATION; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG ISOLATION; DRUG STRUCTURE; LIGAND BINDING; MYCELIUM; NONHUMAN; STREPTOMYCES;

ANTHRAQUINONES; DIABETES MELLITUS, TYPE 2; HUMANS; HYDROCARBONS, CHLORINATED; INHIBITORY CONCENTRATION 50; LUCIFERASES; MOLECULAR STRUCTURE; PPAR GAMMA; STREPTOMYCES; THIAZOLIDINEDIONES;

STREPTOMYCES SP.;

EID: 38349054053     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np070498j     Document Type: Article

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