-
1
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med. 1996;2:561-566.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
2
-
-
0030031766
-
Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative
-
Buchdunger E, Zimmermann J, Mett H, et al. Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res. 1996;56:100-104.
-
(1996)
Cancer Res
, vol.56
, pp. 100-104
-
-
Buchdunger, E.1
Zimmermann, J.2
Mett, H.3
-
3
-
-
0036463948
-
Perspectives on the development of a molecularly targeted agent
-
Druker BJ. Perspectives on the development of a molecularly targeted agent. Cancer Cell. 2002;1:31-36.
-
(2002)
Cancer Cell
, vol.1
, pp. 31-36
-
-
Druker, B.J.1
-
4
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031-1037.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
5
-
-
0001566710
-
A phase II study of STI571 in adult patients with Philadelphia chromosome positive chronic myeloid leukemia in accelerated phase [abstract]
-
Talpaz M, Silver RT, Druker B, et al. A phase II study of STI571 in adult patients with Philadelphia chromosome positive chronic myeloid leukemia in accelerated phase [abstract]. Blood. 2000;96:470a.
-
(2000)
Blood
, vol.96
-
-
Talpaz, M.1
Silver, R.T.2
Druker, B.3
-
6
-
-
0001338423
-
A phase 11 study to determine the safety and anti-leukemic effects of STI571 in patients with Philadelphia chromosome positive chronic myeloid leukemia in myeloid blast crisis [abstract]
-
Sawyers C, Hochhaus A, Feldman E, et al. A phase 11 study to determine the safety and anti-leukemic effects of STI571 in patients with Philadelphia chromosome positive chronic myeloid leukemia in myeloid blast crisis [abstract]. Blood. 2000;96:470a.
-
(2000)
Blood
, vol.96
-
-
Sawyers, C.1
Hochhaus, A.2
Feldman, E.3
-
7
-
-
0034951384
-
STI571: Targeting BCR-ABL as therapy for CML
-
Mauro MJ, Druker BJ. STI571: targeting BCR-ABL as therapy for CML. Oncologist. 2001;6:233-238.
-
(2001)
Oncologist
, vol.6
, pp. 233-238
-
-
Mauro, M.J.1
Druker, B.J.2
-
8
-
-
0035810148
-
Effects of tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al. Effects of tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med. 2001;344:1052-1056.
-
(2001)
N Engl J Med
, vol.344
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
-
9
-
-
0000244046
-
Evaluation of the safety and efficacy of an oral molecularly-targeted therapy, STI571, in patients with unresectable or metastatic gastrointestinal stromal tumors (GISTS) expressing c-kit (CD117) [abstract]
-
Blanke CD, von Mehren M, Joensuu H, et al. Evaluation of the safety and efficacy of an oral molecularly-targeted therapy, STI571, in patients with unresectable or metastatic gastrointestinal stromal tumors (GISTS) expressing c-kit (CD117) [abstract]. Proc Am Soc Clin Oncol. 2001;20:1a.
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Blanke, C.D.1
von Mehren, M.2
Joensuu, H.3
-
10
-
-
10244257546
-
Imatinib and pegylated human recombinant interferon-α2b in early chronic-phase chronic myeloid leukemia
-
for the GIMEMA Working Party on Chronic Myeloid Leukemia
-
Baccarani M, Martinelli G, Rosti G, et al, for the GIMEMA Working Party on Chronic Myeloid Leukemia. Imatinib and pegylated human recombinant interferon-α2b in early chronic-phase chronic myeloid leukemia. Blood. 2004;104:4245-4251.
-
(2004)
Blood
, vol.104
, pp. 4245-4251
-
-
Baccarani, M.1
Martinelli, G.2
Rosti, G.3
-
11
-
-
10744228340
-
Imatinib mesylate therapy of chronic phase chronic myeloid leukemia resistant or intolerant to interferon: Results and prognostic factors for response and progression-free survival in 150 patients
-
Cervantes F, Hernández-Boluda JC, Steegmann JL, et al. Imatinib mesylate therapy of chronic phase chronic myeloid leukemia resistant or intolerant to interferon: results and prognostic factors for response and progression-free survival in 150 patients. Haematologica. 2003;88:1117-1122.
-
(2003)
Haematologica
, vol.88
, pp. 1117-1122
-
-
Cervantes, F.1
Hernández-Boluda, J.C.2
Steegmann, J.L.3
-
12
-
-
9144253153
-
Dynamics of BCR-ABL mRNA expression in first-line therapy of chronic myelogenous leukemia patients with imatinib or interferon α/ara-C
-
Müller MC, Gattermann N, Lahaye T, et al. Dynamics of BCR-ABL mRNA expression in first-line therapy of chronic myelogenous leukemia patients with imatinib or interferon α/ara-C. Leukemia. 2003;17:2392-2400.
-
(2003)
Leukemia
, vol.17
, pp. 2392-2400
-
-
Müller, M.C.1
Gattermann, N.2
Lahaye, T.3
-
13
-
-
0037103002
-
Severe periorbital edema secondary to STI571 (Gleevec)
-
Esmaeli B, Prieto VG, Butler CE, et al. Severe periorbital edema secondary to STI571 (Gleevec). Cancer. 2002;95:881-887.
-
(2002)
Cancer
, vol.95
, pp. 881-887
-
-
Esmaeli, B.1
Prieto, V.G.2
Butler, C.E.3
-
14
-
-
0041971163
-
Ocular side-effects associated with imatinib mesylate (Gleevec)
-
Fraunfelder FW, Solomon J, Druker BJ, Esmaeli B, Kuyl J. Ocular side-effects associated with imatinib mesylate (Gleevec). J Ocul Pharmacol Ther. 2003;19:371-375.
-
(2003)
J Ocul Pharmacol Ther
, vol.19
, pp. 371-375
-
-
Fraunfelder, F.W.1
Solomon, J.2
Druker, B.J.3
Esmaeli, B.4
Kuyl, J.5
-
15
-
-
20844441783
-
Periorbital oedema and epiphora as ocular side effects of imatinib mesylate (Gleevec)
-
Esmaeli B, Diba R, Ahmadi MA, et al. Periorbital oedema and epiphora as ocular side effects of imatinib mesylate (Gleevec). Eye. 2004;18:760-762.
-
(2004)
Eye
, vol.18
, pp. 760-762
-
-
Esmaeli, B.1
Diba, R.2
Ahmadi, M.A.3
-
16
-
-
0025021215
-
Proposal for a simple synthesis prognostic staging system in chronic myelogenous leukemia
-
Kantarjian HM, Keating MJ, Smith TL, Talpaz M, McCredie KB. Proposal for a simple synthesis prognostic staging system in chronic myelogenous leukemia. Am J Med. 1990;88:1-8.
-
(1990)
Am J Med
, vol.88
, pp. 1-8
-
-
Kantarjian, H.M.1
Keating, M.J.2
Smith, T.L.3
Talpaz, M.4
McCredie, K.B.5
-
17
-
-
11144354274
-
High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome-positive chronic phase chronic myeloid leukemia
-
Kantarjian H, Talpaz M, O'Brien S, et al. High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome-positive chronic phase chronic myeloid leukemia. Blood. 2004;103:2873-2888.
-
(2004)
Blood
, vol.103
, pp. 2873-2888
-
-
Kantarjian, H.1
Talpaz, M.2
O'Brien, S.3
|