Interleukin-8 Is Increased in Gingival Crevicular Fluid from Patients with Acute Pulpitis

Journal of Endodontics

Volumn 34, Issue 2, 2008, Pages 148-151

  Karapanou, Virginia ^a   Kempuraj, Duraisamy ^b   Theoharides, Theoharis C ^b  

^a TUFTS UNIVERSITY SCHOOL OF DENTAL MEDICINE   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CXCL8; gingival crevicular fluid; irreversible pulpitis; neurogenic inflammation; pain; TNF

Indexed keywords

INTERLEUKIN 8; LIDOCAINE; LOCAL ANESTHETIC AGENT; TUMOR NECROSIS FACTOR ALPHA;

ACUTE DISEASE; ADULT; ARTICLE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; FEMALE; GINGIVITIS; HUMAN; MALE; MANDIBULAR NERVE; METABOLISM; MIDDLE AGED; NERVE BLOCK; PAIN ASSESSMENT; PULPITIS;

ACUTE DISEASE; ADULT; ANESTHETICS, LOCAL; FEMALE; GINGIVAL CREVICULAR FLUID; HUMANS; INTERLEUKIN-8; LIDOCAINE; MALE; MANDIBULAR NERVE; MIDDLE AGED; NERVE BLOCK; PAIN MEASUREMENT; PULPITIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 38349049475     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2007.10.022     Document Type: Article

References (32)

1. Seltzer S., Bender I.B., and Ziontz M. The dynamics of pulp inflammation: correlations between diagnostic data and actual histologic findings in the pulp. Oral Surg Oral Med Oral Pathol 16 (1963) 846-871
2. Pulver W.H., Taubman M.A., and Smith D.J. Immune components in normal and inflamed human dental pulp. Arch Oral Biol 22 (1977) 103-111
3. Trowbridge H.O. Pathogenesis of pulpitis resulting from dental caries. J Endod 7 (1981) 52-60
4. Hahn C.L., Best A.M., and Tew J.G. Cytokine induction by Streptococcus mutans and pulpal pathogenesis. Infect Immun 68 (2000) 6785-6789
5. Wakisaka S. Neuropeptides in the dental pulp: distribution, origins, and correlation. J Endod 16 (1990) 67-69
6. Cao Y.Q., Mantyh P.W., Carlson E.J., Gillespie A., Epstein C.J., and Basbaum A.I. Primary afferent tachykinins are required to experience moderate to intense pain. Nature 392 (1998) 390-394
7. Stashenko P., Teles R., and D'Souza R. Periapical inflammatory responses and their modulation. Crit Rev Oral Biol Med 9 (1998) 498-521
8. Möller A., Lippert U., Lessmann D., et al. Human mast cells produce IL-8. J Immunol 151 (1993) 3261-3266
9. Galli S.J., Nakae S., and Tsai M. Mast cells in the development of adaptive immune responses. Nat Immunol 6 (2005) 135-142
10. Theoharides T.C., and Cochrane D.E. Critical role of mast cells in inflammatory diseases and the effect of acute stress. J Neuroimmunol 146 (2004) 1-12
11. Huang G.T., Potente A.P., Kim J.W., Chugal N., and Zhang X. Increased interleukin-8 expression in inflamed human dental pulps. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 88 (1999) 214-220
12. Park S.H., Hsiao G.Y., and Huang G.T. Role of substance P and calcitonin gene-related peptide in the regulation of interleukin-8 and monocyte chemotactic protein-1 expression in human dental pulp. Int Endod J 37 (2004) 185-192
13. Zehnder M., Delaleu N., Du Y., and Bickel M. Cytokine gene expression: part of host defence in pulpitis. Cytokine 22 (2003) 84-88
14. Pezelj-Ribaric S., Anic I., Brekalo I., Miletic I., Hasan M., and Simunovic-Soskic M. Detection of tumor necrosis factor alpha in normal and inflamed human dental pulps. Arch Med Res 33 (2002) 482-484
15. Awawdeh L.A., Lundy F.T., Linden G.J., Shaw C., Kennedy J.G., and Lamey P.J. Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in gingival crevicular fluid associated with painful human teeth. Eur J Oral Sci 110 (2002) 185-191
16. Patel T., Park S.H., Lin L.M., Chiappelli F., and Huang G.T. Substance P induces interleukin-8 secretion from human dental pulp cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96 (2003) 478-485
17. Nagaoka S., Tokuda M., Sakuta T., et al. Interleukin-8 gene expression by human dental pulp fibroblast in cultures stimulated with Prevotella intermedia lipopolysaccharide. J Endod 22 (1996) 9-12
18. Remick D.G. Interleukin-8. Crit Care Med 33 (2005) S466-S467
19. Tran M.T., Lausch R.N., and Oakes J.E. Substance P differentially stimulates IL-8 synthesis in human corneal epithelial cells. Invest Ophthalmol Vis Sci 41 (2000) 3871-3877
20. Goebeler M., Henseleit U., Roth J., and Sorg C. Substance P and calcitonin gene-related peptide modulate leukocyte infiltration to mouse skin during allergic contact dermatitis. Arch Dermatol Res 286 (1994) 341-346
21. Tancharoen S., Sarker K.P., and Imamura T. Neuropeptide release from dental pulp cells by RgpB via proteinase-activated receptor-2 signaling. J Immunol 174 (2005) 5796-5804
22. Zhao D., Kuhnt-Moore S., Zeng H., et al. Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases. Biochem 368 (2002) 665-672
23. Mehrad B., Strieter R.M., Moore T.A., Tsai W.C., Lira S.A., and Standiford T.J. CXC chemokine receptor-2 ligands are necessary components of neutrophil-mediated host defense in invasive pulmonary aspergillosis. J Immunol 163 (1999) 6086-6094
24. Rodd H.D., and Boissonade F.M. Substance P expression in human tooth pulp in relation to caries and pain experience. Eur J Oral Sci 108 (2000) 467-474
25. Lan W., Harmon D.C., Wang J.H., Shorten G.D., and Redmond P.H. Activated endothelial interleukin-1beta, -6, and -8 concentrations and intercellular adhesion molecule-1 expression are attenuated by lidocaine. Anesth Analg 100 (2005) 409-412
26. Lahav M., Levite M., Bassani L., et al. Lidocaine inhibits secretion of IL-8 and IL-1beta and stimulates secretion of IL-1 receptor antagonist by epithelial cells. Clin Exp Immunol 127 (2002) 226-233
27. Taniguchi T., Shibata K., Yamamoto K., Mizukoshi Y., and Kobayashi T. Effects of lidocaine administration on hemopdynamics and cytokine responses to endotoxemia in rabbits. Crit Care Med 28 (2000) 755-759
28. Kim S., Edwall L., Trowbridge H., and Chien S. Effects of local anesthetics on pulpal blood flow in dogs. J Dent Res 63 (1984) 650-652
29. Troullos E.S., Hargreaves K.M., Goldstein D.S., Stull R., and Dionne R.A. Epinephrine suppresses stress-induced increases in plasma immunoreactive beta-endorphin in humans. J Clin Endocrinol Metab 69 (1989) 546-551
30. Owatz C.B., Khan A.A., Schindler W.G., Schwartz S., Keiser K., and Hargreaves K.M. The incidence of mechanical allodynia in patients with irreversible pulpitis. J Endod 33 (2007) 552-558
31. Hahn C., and Liewehr F.R. Update on the adaptive immune responses of the dental pulp. J Endod 33 (2007) 773-781
32. Theoharides T.C., Kempuraj D., Tagen M., Conti P., and Kalogeromitros D. Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol Rev 217 (2007) 65-78