Embryonic stem cells cultured in serum-free medium acquire bovine apolipoprotein B-100 from feeder cell layers and serum replacement medium

Stem Cells

Volumn 26, Issue 1, 2008, Pages 72-78

  Hisamatsu Sakamoto, Michiko ^a,b   Sakamoto, Norihisa ^a,b   Rosenberg, Amy S ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

Apolipoprotein B 100; Conditioned medium; Fetal calf serum; Low density lipoproteins; Murine embryonic fibroblasts

Indexed keywords

APOLIPOPROTEIN B100; LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANTIBODY RESPONSE; ARTICLE; CELL CULTURE; CELL POPULATION; CELL PROLIFERATION; CELL SURFACE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FETAL CALF SERUM; FLOW CYTOMETRY; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; WESTERN BLOTTING;

ANIMALS; ANTIGENS, HETEROPHILE; APOLIPOPROTEIN B-100; BLOTTING, WESTERN; CATTLE; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CULTURE MEDIA; EMBRYONIC STEM CELLS; FIBROBLASTS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOPRECIPITATION; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL;

ANIMALIA; BOVINAE; MURINAE;

EID: 38349032696     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0744     Document Type: Article

References (43)

1. D'Amour K, Gage FH. New tools for human developmental biology. Nat Biotechnol 2000;18:381-382.
2. Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145-1147.
3. Bradley JA, Bolton EM, Pedersen RA. Stem cell medicine encounters the immune system. Nat Rev Immunol 2002;2:859-871.
4. Swijnenburg RJ, Tanaka M, Vogel H et al. Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium. Circulation 2005;112:I166-172.
5. Hentze H, Graichen R, Colman A. Cell therapy and the safety of embryonic stem cell-derived grafts. Trends Biotechnol 2007;25:24-32.
6. Mannello F, Tonti GA. Concise review: No breakthroughs for human mesenchymal and embryonic stem cell culture: Conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serum-free, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold! STEM CELLS 2007;25:1603-1609.
7. Moore H. The medium is the message. Nat Biotechnol 2006;24:160-161.
8. Sakamoto N, Kazuhide T, Linda MM et al. Bovine apolipoprotein B-100 is a dominant immunogen in therapeutic cell populations cultured in FCS in mice and humans. Blood 2007;110:501-508.
9. Hevonoja T, Pentikainen MO, Hyvonen MT et al. Structure of low density lipoprotein (LDL) particles: Basis for understanding molecular changes in modified LDL. Biochim Biophys Acta 2000;1488:189-210.
10. Howell BW, Herz J. The LDL receptor gene family: Signaling functions during development. Curr Opin Neurobiol 2001;11:74-81.
11. Gustafsson M, Borén J. Mechanism of lipoprotein retention by the extracellular matrix. Curr Opin Lipidol 2004;15:505-514.
12. Chung NS, Wasan KM. Potential role of the low-density lipoprotein receptor family as mediators of cellular drug uptake. Adv Drug Deliv Rev 2004;56:1315-1334.
13. Spector AA, Mathur SN, Kaduce TL et al. Lipid nutrition and metabolism of culture mammalian cells. Prog Lipid Res 1980;19:155-186.
14. Solter D, Knowles BB. Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proc Natl Acad Sci U S A 1978;75:5565-5569.
15. Loeffler B, Heeren J, Blaeser M et al. Lipoprotein lipase-facilitated uptake of LDL is mediated by the LDL receptor. J Lipid Res 2007;48:288-298.
16. Mulder M, Lombardi P, Jansen H et al. Low density lipoprotein receptor internalizes low density and very low density lipoproteins that are bound to heparan sulfate proteoglycans via lipoprotein lipase. J Biol Chem 1993;268:9369-2375.
17. Invitrogen Corp. KnockOutSR: Serum Replacement for Embryonic Stem Cells [Instruction leaflets]. Gibco/Invitrogen Corp. 2001; Carlsbad, CA.
18. Martin MJ, Muotri A, Gage F et al. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med 2005;11:228-232.
19. Tangvoranuntakul P, Gagneux P, Diaz S et al. Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid. Proc Natl Acad Sci U S A 2003;100:12045-12050.
20. Richards M, Fong CY, Chan WK et al. Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nat Biotechnol 2002;20:933-936.
21. Amit M, Margulets V, Segev K et al. Human feeder layers for human embryonic stem cells. Biol Reprod 2003;68:2150-2156.
22. Cheng L, Hammond H, Ye Z et al. Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture. STEM CELLS 2003;21:131-142.
23. Xu C, Inokuma MS, Denham J et al. Feeder-free growth of undifferentiated human embryonic stem cells. Nat Biotechnol 2001;19:971-974.
24. Amit M, Sharki C, Margulets V et al. Feeder layer- and serum-free culture of human embryonic stem cells. Biol Reprod 2004;70:837-845.
25. Price P, Goldsborough M, Tilkins ML, inventors; Life Technologies, Inc., assignee. Embryonic stem cell serum replacer. W./1998/030679. July 16, 1998.
26. Llorente-Cortés V, Otero-Viñas M, Badimon L. Differential role of heparan sulfate proteoglycans on aggregated LDL uptake in human vascular smooth muscle cells and mouse embryonic fibroblasts. Arterioscler Thromb Vasc Biol 2002;22:1905-1911.
27. Lim JW, Bodnar A. Proteome analysis of conditioned medium from mouse embryonic fibroblast feeder layers which support the growth of human embryonic stem cells. Proteomics 2002;2:1187-1203.
28. Ibrahimi OA, Zhang F, Hrstka SC et al. Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly. Biochemistry 2004;43:4724-4730.
29. Jiao X, Billings PC, O'Connell MP et al. Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells. WO/1998/030679. July 16, 1998. J Biol Chem 2007;282:1080-1084.
30. Emmanuele L, Ortmann J, Doerflinger T et al. Lovastatin stimulates human vascular smooth muscle cell expression of bone morphogenetic protein-2, a potent inhibitor of low-density lipoprotein-stimulated cell growth. Biochem Biophys Res Commun 2003;302:67-72.
31. Lianguzova MS, Chuykin IA, Nordheim A et al. Phosphoinositide 3-kinase inhibitor LY294002 but not serum withdrawal suppresses proliferation of murine embryonic stem cells. Cell Biol Int 2007;31:330-337.
32. Schratt G, Weinhold B, Lundberg AS et al. Serum response factor is required for immediate-early gene activation yet is dispensable for proliferation of embryonic stem cells. Mol Cell Biol 2001;21:2933-2943.
33. Hayavi S, Halbert GW. Synthetic low-density lipoprotein, a novel biomimetic lipid supplement for serum-free tissue culture. Biotechnol Prog 2005;21:1262-1268.
34. Sato JD, Kawamoto T, McClure DB et al. Cholesterol requirement of NS-1 mouse myeloma cells for growth in serum-free medium. Mol Biol Med 1984;2:121-134.
35. Gorfien S, Paul B, Walowitz J et al. Growth of NS0 cells in protein-free, chemically defined medium. Biotechnol Prog 2000;16:682-687.
36. Spens E, Häggström L. Defined protein-free NS0 myeloma cell cultures: Stimulation of proliferation by conditioned medium factors. Biotechnol Prog 2005;21:87-95.
37. Okonkowski J, Balasubramanian U, Seamans C et al. Cholesterol delivery to NS0 cells: Challenges and solutions in disposable linear low-density polyethylene-based bioreactors. J Biosci Bioeng 2007;103:50-59.
38. Ellerström C, Strehl R, Moya K et al. Derivation of a xeno-free human embryonic stem cell line. STEM CELLS 2006;24:2170-2176.
39. Ludwig TE, Levenstein ME, Jones JM et al. Derivation of human embryonic stem cells in defined conditions. Nat Biotechnol 2006;24:185-187.
40. Rajala K, Hakala H, Panula S et al. Testing of nine different xeno-free culture media for human embryonic stem cell cultures. Hum Reprod 2007;22:1231-1238.
41. Berg K, Powell LM, Wallis SC et al. Genetic linkage between the antigenic group (Ag) variation and the apolipoprotein B gene: Assignment of the Ag locus. Proc Natl Acad Sci U S A 1986;83:7367-7370.
42. Wu MJ, Bütler E, Bütler R et al. Identification of the base substitution responsible for the Ag(x/y) polymorphism of apolipoprotein B-100. Arterioscler Thromb 1991;11:379-384.
43. Cooper DK, Dorling A, Pierson RN 3rd et al. Alpha1,3- galactosyltransferase gene-knockout pigs for xenotransplantation: Where do we go from here? Transplantation 2007;84:1-7.