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Volumn 130, Issue 1, 2008, Pages 8-9

Hydrogen-Deuterium Exchange and Selective Labeling of Deprotonated Amino Acids and Peptides in the Gas Phase

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; DEUTERIUM; HYDROGEN; PEPTIDE DERIVATIVE;

EID: 38349030729     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja076599l     Document Type: Article
Times cited : (13)

References (27)
  • 7
    • 38349069626 scopus 로고    scopus 로고
    • Reed, D. R. Ph.D. Thesis, University of Minnesota, Minneapolis, MN, 2001.
    • Reed, D. R. Ph.D. Thesis, University of Minnesota, Minneapolis, MN, 2001.
  • 12
    • 38349005493 scopus 로고    scopus 로고
    • Incorporation of an additional deuterium was not observed under any of the conditions that were employed and has a rate constant of less than 2 × 10-13 cm3 molecule-1 s-1. That is, it occurs at least 2 orders of magnitude or more slowly than the observed exchanges
    • -1. That is, it occurs at least 2 orders of magnitude or more slowly than the observed exchanges.
  • 13
    • 38349012422 scopus 로고    scopus 로고
    • The reported rates are the average of three measurements and have uncertainties which are assumed to be ±30
    • The reported rates are the average of three measurements and have uncertainties which are assumed to be ±30%.
  • 14
    • 0003464216 scopus 로고    scopus 로고
    • For gas-phase acidities, see:, Mallard, W. G, Linstrom, P. J, Eds, National Institute of Standards and Technology: Gaithersburg, MD 20899
    • For gas-phase acidities, see: Bartmess, J. E. NIST Chemistry WebBook, NIST Standard Reference Database Number 69; Mallard, W. G., Linstrom, P. J., Eds.; National Institute of Standards and Technology: Gaithersburg, MD 20899 (http://webbook.nist.gov).
    • NIST Chemistry WebBook, NIST Standard Reference Database Number 69
    • Bartmess, J.E.1
  • 15
    • 0008138842 scopus 로고    scopus 로고
    • The carboxyl groups of some protonated amino acids undergo exchange more rapidly than the other labile hydrogens. See refs 3, 5, and the following: (a) Gard, E, Willard, D, Bregar, J, Green, M. K, Lebrilla, C. B. Org. Mass Spectrom. 1993, 28, 1632-1639
    • The carboxyl groups of some protonated amino acids undergo exchange more rapidly than the other labile hydrogens. See refs 3, 5, and the following: (a) Gard, E.; Willard, D.; Bregar, J.; Green, M. K.; Lebrilla, C. B. Org. Mass Spectrom. 1993, 28, 1632-1639.
  • 18
    • 0008040940 scopus 로고    scopus 로고
    • Partial labeling of large peptide M + H ions is well-known. (a) Winger, B. E.; Light-Wahl, K. J.; Rockwood, A. L.; Smith, R. D. J. Am. Chem. Soc. 1992, 114, 5897-5898.
    • Partial labeling of large peptide M + H ions is well-known. (a) Winger, B. E.; Light-Wahl, K. J.; Rockwood, A. L.; Smith, R. D. J. Am. Chem. Soc. 1992, 114, 5897-5898.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.