A new technique for the surgical creation of aneurysms in an in vivo tortuous vessel model to test neurovascular devices

Journal of Investigative Surgery

Volumn 21, Issue 1, 2008, Pages 39-45

  Arends, Jennifer ^a   Perkins, Keith ^a   Zhang, Ji ^a   Polyakov, Igor ^a   Lee, Elaine ^a  

^a BOSTON SCIENTIFIC CORPORATION   (United States)

Author keywords

Aneurysm model; Animal model; Carotid siphon; Endovascular treatment; Intracranial aneurysms; Intracranial vasculature; Swine; Tortuous anatomy

Indexed keywords

ACETYLSALICYLIC ACID; BUPRENORPHINE; CLOPIDOGREL; ENROFLOXACIN; HEPARIN; NIFEDIPINE; POLITEF;

ANEURYSM SURGERY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICOAGULATION; ARTICLE; BLOOD VESSEL GRAFT; BRAIN ANGIOGRAPHY; BRAIN ARTERY ANEURYSM; BRAIN BLOOD VESSEL; CEREBROVASCULAR DISEASE; COIL EMBOLIZATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; DISEASE MODEL; ENDOVASCULAR SURGERY; FEEDBACK SYSTEM; HISTOPATHOLOGY; IN VIVO STUDY; JUGULAR VEIN; NEUROSURGERY; NONHUMAN; PRIORITY JOURNAL; STENT; SURGICAL ANATOMY; SURGICAL APPROACH; SURGICAL EQUIPMENT; SURGICAL TECHNIQUE; SURVIVAL RATE; SUTURING METHOD; SWINE; VEIN GRAFT;

ANIMALS; CAROTID ARTERY, COMMON; DISEASE MODELS, ANIMAL; INTRACRANIAL ANEURYSM; STENTS; SWINE;

EID: 38349022500     PISSN: 08941939     EISSN: 15210553     Source Type: Journal    
DOI: 10.1080/08941930701834189     Document Type: Article

References (9)

1. Miskolczi, L., Guterman, L. R., Flaherty, J. D. and Hopkins, L. N. (1998) Saccular aneurysm induction by elastase digestion of the arterial wall: A new animal model. Neurosurgery, 43:3, pp. 595-600.
2. Altes, T. A., Cloft, H. J. and Short, J. G. (2000) 1999 ARRS Executive Council Award. Creation of saccular aneurysms in the rabbit: A model suitable for testing endovascular devices. American Roentgen Ray Society. AJR Am J Roentgenol., 174:2, pp. 349-354.
3. Graves, V. B., Partington, C. R., Rufenacht, D. A., Rappe, A. H. and Strother, C. M. (1990) Treatment of carotid artery aneurysms with platinum coils: An experimental study in dogs. AJNR Am J Neuroradiol., 11:2, pp. 249-252.
4. German, W. J. and Black, S. P. (1954) Experimental production of carotid aneurysms. N Engl J Med., 250:3, pp. 104-106.
5. Kerber, C. W. and Buschman, R. W. (1977) Experimental carotid aneurysms: I. Simple surgical production and radiographic evaluation. Invest Radiol., 12:2, pp. 154-157.
6. Akiba, Y., Murayama, Y., Vinuela, F., Lefkowitz, M. A., Duckwiler, G. R. and Gobin, Y. P. (1999) Balloon-assisted Guglielmi detachable coiling of wide-necked aneurysms: Part I-Experimental evaluation. Neurosurgery, 45:3, pp. 519-527.
7. Georganos, S. A., Guilbert, F., Salazkin, I., Gevry, G. and Raymond, J. (2004) Surgical construction of an in vivo carotid siphon model to test neurovascular devices. Neurosurgery, 54:5, pp. 1239-1243.
8. Institute, o. f. (1996) Laboratory Animal Resources, Commission on Life Sciences, National Research Counsel. Guidelines for the Care and Use of Laboratory Animals, National Academy Press, Washington, DC
9. Levy, E. I., Boulos, A. S. and Hanel, R. A. (2003) In vivo model of intracranial stent implantation: A pilot study to examine the histological response of cerebral vessels after randomized implantation of heparin-coated and uncoated endoluminal stents in a blinded fashion. J Neurosurg., 98:3, pp. 544-553.