Histone modifications associated with herpes simplex virus type 1 genomes during quiescence and following ICP0-mediated de-repression

Journal of General Virology

Volumn 89, Issue 1, 2008, Pages 68-77

  Coleman, Heather M ^a   Connor, Viv ^a   Cheng, Zara S C ^a   Grey, Finn ^a,c   Preston, Chris M ^b   Efstathiou, Stacey ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b INSTITUTE OF VIROLOGY   (United Kingdom)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; HISTONE; HISTONE H3; PROTEIN ANTIBODY; PROTEIN ICP0; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

ACETYLATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DEACETYLATION; GENOME; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SUPERINFECTION; VIRUS INHIBITION; VIRUS REACTIVATION; VIRUS RECOMBINANT;

CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; DENDRITIC CELLS; FIBROBLASTS; GENE EXPRESSION REGULATION, VIRAL; GENOME, VIRAL; HERPESVIRUS 1, HUMAN; HISTONES; HUMANS; IMMEDIATE-EARLY PROTEINS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); TUMOR NECROSIS FACTOR-ALPHA; UBIQUITIN-PROTEIN LIGASES; VIRUS ACTIVATION;

ADENOVIRIDAE; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; SIMPLEXVIRUS;

EID: 38349022497     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.83272-0     Document Type: Article

References (39)

1. Ace, C. I., McKee, T. A., Ryan, J. M., Cameron, J. M. & Preston, C. M. (1989). Construction and characterization of a herpes simplex virus type 1 mutant unable to transinduce immediate-early gene expression. J Virol 63, 2260-2269.
2. Amelio, A. L., Giordani, N. V., Kubat, N. J., O'Neil, J. E. & Bloom, D. C. (2006). Deacetylation of the herpes simplex virus type 1 latency-associated transcript (LAT) enhancer and a decrease in LAT abundance precede an increase in ICP0 transcriptional permissiveness at early times postexplant. J Virol 80, 2063-2068.
3. Arthur, J. L., Scarpini, C. G., Connor, V., Lachmann, R. H., Tolkovsky, A. M. & Efstathiou, S. (2001). Herpes simplex virus type 1 promoter activity during latency establishment, maintenance, and reactivation in primary dorsal root neurons in vitro. J Virol 75, 3885-3895.
4. Bannister, A. J., Zegerman, P., Partridge, J. F., Miska, E. A., Thomas, J. O., Allshire, R. C. & Kouzarides, T. (2001). Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410, 120-124.
5. Bottardi, S., Aumont, A., Grosveld, F. & Milot, E. (2003). Developmental stage-specific epigenetic control of human β-globin gene expression is potentiated in hematopoietic progenitor cells prior to their transcriptional activation. Blood 102, 3989-3997.
6. Deshmane, S. L. & Fraser, N. W. (1989). During latency, herpes simplex virus type 1 DNA is associated with nucleosomes in a chromatin structure. J Virol 63, 943-947.
7. Efstathiou, S. & Preston, C. M. (2005). Towards an understanding of the molecular basis of herpes simplex virus latency. Virus Res 111, 108-119.
8. Everett, R. D. (2000). ICP0, a regulator of herpes simplex virus during lytic and latent infection. Bioessays 22, 761-770.
9. Gu, H., Liang, Y., Mandel, G. & Roizman, B. (2005). Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells. Proc Natl Acad Sci U S A 102, 7571-7576.
10. Hagglund, R. & Roizman, B. (2004). Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1. J Virol 78, 2169-2178.
11. Halford, W. P. & Schaffer, P. A. (2001). ICPO is required for efficient reactivation of herpes simplex virus type 1 from neuronal latency. J Virol 75, 3240-3249.
12. Harris, R. A. & Preston, C. M. (1991). Establishment of latency in vitro by the herpes simplex virus type 1 mutant in1814. J Gen Virol 72, 907-913.
13. Harris, R. A., Everett, R. D., Zhu, X. X., Silverstein, S. & Preston, C. M. (1989). Herpes simplex virus type 1 immediate-early protein Vmw110 reactivates latent herpes simplex virus type 2 in an in vitro latency system. J Virol 63, 3513-3515.
14. Herrera, F. J. & Triezenberg, S. J. (2004). VP16-dependent association of chromatin-modifying coactivators and underrepresentation of histones at immediate-early gene promoters during herpes simplex virus infection. J Virol 78, 9689-9696.
15. Hobbs, W. E., Brough, D. E., Kovesdi, I. & DeLuca, N. A. (2001). Efficient activation of viral genomes by levels of herpes simplex virus ICP0 insufficient to affect cellular gene expression or cell survival. J Virol 75, 3391-3403.
16. Homer, E. G., Rinaldi, A., Nicholl, M. J. & Preston, C. M. (1999). Activation of herpesvirus gene expression by the human cytomegalo-virus protein pp71. J Virol 73, 8512-8518.
17. Jamieson, D. R., Robinson, L. H., Daksis, J. I., Nicholl, M. I & Preston, C. M. (1995). Quiescent viral genomes in human fibroblasts after infection with herpes simplex virus type 1 Vmw65 mutants. J Gen Virol 76, 1417-1431.
18. Jenuwein, T. & Allis, C. D. (2001). Translating the histone code. Science 293, 1074-1080.
19. Kent, J. R., Zeng, P. Y., Atanasiu, D., Gardner, J., Fraser, N. W. & Berger, S. L. (2004). During lytic infection herpes simplex virus type 1 is associated with histories bearing modifications that correlate with active transcription. J Virol 78, 10178-10186.
20. Kouzarides, T. (2002). Histone methylation in transcriptional control. Curr Opin Genet Dev 12, 198-209.
21. Kubat, N. J., Tran, R. K., McAnany, P. & Bloom, D. C. (2004a). Specific histone tail modification and not DNA methylation is a determinant of herpes simplex virus type 1 latent gene expression. J Virol 78, 1139-1149.
22. Kubat, N. J., Amelio, A. L., Giordani, N. V. & Bloom, D. C. (2004b). The herpes simplex virus type 1 latency- associated transcript (LAT) enhancer/rcr is hyperacetylated during latency independently of LAT transcription. J Virol 78, 12508-12518.
23. Leib, D. A., Coen, D. M., Bogard, C. L., Hicks, K. A., Yager, D. R., Knipe, D. M., Tyler, K. L. & Schaffer, P. A. (1989). Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. J Virol 63, 759-768.
24. Lomonte, P., Thomas, J., Texier, P., Caron, C., Khochbin, S. & Epstein, A. L. (2004). Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1. J Virol 78, 6744-6757.
25. McFarlane, M., Daksis, J. I. & Preston, C. M. (1992). Flexamethylene bisacetamide stimulates herpes simplex virus immediate early gene expression in the absence of trans-induction by Vmw65. J Gen Virol 73, 285-292.
26. Minaker, R. L., Mossman, K. L. & Smiley, J. R. (2005). Functional inaccessibility of quiescent herpes simplex virus genomes. Virol J 2, 85.
27. Murphy, J. C., Fischle, W., Verdin, E. & Sinclair, J. H. (2002). Control of cytomegalovirus lytic gene expression by histone acetylation. EMBO J 21, 1112-1120.
28. Nitsche, A., Becker, M., Junghahn, I., Aumann, J., Landt, O., Fichtner, I., Wittig, B. & Siegert, W. (2001). Quantification of human cells in NOD/SCID mice by duplex real-time polymerase-chain reaction. Haematologica 86, 693-699.
29. Pokholok, D. K., Harbison, C. T., Levine, S., Cole, M., Hannett, N. M., Lee, T. I., Bell, G. W., Walker, K., Rolfe, P. A. & other authors (2005). Genome-wide map of nucleosome acetylation and methylation in yeast. Cell 122, 517-527.
30. Preston, C. M. (2000). Repression of viral transcription during herpes simplex virus latency. J Gen Virol 81, 1-19.
31. Preston, C. M. & Nicholl, M. J. (1997). Repression of gene expression upon infection of cells with herpes simplex virus type 1 mutants impaired for immediate-early protein synthesis. J Virol 71, 7807-7813.
32. Reeves, M. B., MacAry, P. A., Lehner, P. J., Sissons, J. G. & Sinclair, J. H. (2005). Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers. Proc Natl Acad Sci U S A 102, 4140-4145.
33. Reeves, M., Murphy, J., Greaves, R., Fairley, J., Brehm, A. & Sinclair, J. H. (2006). Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86. J Virol 80, 9998-10009.
34. Samaniego, L. A., Neiderhiser, L. & DeLuca, N. A. (1998). Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins. J Virol 72, 3307-3320.
35. Stow, N. D. & Stow, E. C. (1986). Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110. J Gen Virol 67, 2571-2585.
36. Suzuki, M., Kasai, K. & Saeki, Y. (2006). Plasmid DNA sequences present in conventional herpes simplex virus amplicon vectors cause rapid transgene silencing by forming inactive chromatin. J Virol 80, 3293-3300.
37. Thompson, R. L. & Sawtell, N. M. (2006). Evidence that the herpes simplex virus type 1 ICPO protein does not initiate reactivation from latency in vivo. J Virol 80, 10919-10930.
38. Wang, Q. Y., Zhou, C., Johnson, K. E., Colgrove, R. C., Coen, D. M. & Knipe, D. M. (2005). Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection. Proc Natl Acad Sci U S A 102, 16055-16059.
39. Zhu, X. X., Chen, J. X., Young, C. S. & Silverstein, S. (1990). Reactivation of latent herpes simplex virus by adenovirus recombinants encoding mutant IE-0 gene products. J Virol 64, 4489-4498.