Inflammatory mediators in diabetic and non-diabetic lumbosacral radiculoplexus neuropathy

Acta Neuropathologica

Volumn 115, Issue 2, 2008, Pages 231-239

  Kawamura, Nobutoshi ^a,b   Dyck, P James B ^a   Schmeichel, Ann M ^a   Engelstad, JaNean K ^a   Low, Phillip A ^a   Dyck, Peter J ^a  

^a MAYO CLINIC   (United States)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Diabetic amyotrophy; Diabetic lumbosacral radiculoplexus neuropathy; Intercellular adhesion molecule 1; Nuclear factor kappa B; Peripheral neuropathy; Tumor necrosis factor

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEUROPATHY; DISEASE ASSOCIATION; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNOCHEMISTRY; LUMBOSACRAL PLEXUS NEUROPATHY; MAJOR CLINICAL STUDY; MALE; NERVE BIOPSY; NERVE FIBER DEGENERATION; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SURAL NERVE; UPREGULATION;

AGED; DIABETES MELLITUS; DIABETIC NEUROPATHIES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; LUMBOSACRAL PLEXUS; MALE; MIDDLE AGED; NF-KAPPA B; POLYRADICULOPATHY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 38349018274     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-007-0326-2     Document Type: Article

References (38)

1. Andorfer B, Kieseier BC, Mathey E, Armati P, Pollard J, Oka N, Hartung HP (2001) Expression and distribution of transcription factor NF-kappaB and inhibitor IkappaB in the inflamed peripheral nervous system. J Neuroimmunol 116:226-232
2. Asbury AK (1977) Proximal diabetic neuropathy. Ann Neurol 2:179-180
3. Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M (1995) Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis (see comment). Science 270:286-290
4. Bastron JA, Thomas JE (1981) Diabetic polyradiculopathy: Clinical and electromyographic findings in 105 patients. Mayo ClinProc 56:725-732
5. Bonetti B, Valdo P, Stegagno C, Tanel R, Zanusso GL, Ramarli D, Fiorini E, Turazzi S, Carner M, Moretto G (2000) Tumor necrosis factor alpha and human Schwann cells: Signalling and phenotype modulation without cell death. J Neuropathol Exp Neurol 59(1):74-84
6. Chokroverty S, Reyes MG, Rubino FA (1977) Bruns-Garland syndrome of diabetic amyotrophy. Trans Am Neurol Assoc 102:173-177
7. Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T (1995) Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J 9:899-909
8. Deprez M, Lubke U, Verlaet M, Debrus S, Delvenne P, Martin JJ (2001) Detection of cytokines in human sural nerve biopsies: An immunohistochemical and molecular study. Acta Neuropathol (Berl) 101(4):393-404
9. Dyck PJ, Dyck PJB, Engelstad J (2005) Pathologic alterations of nerves. In: Dyck PJ, Thomas PK (eds Peripheral neuropathy, 4th edn. Elsevier, Philadelphia, pp 733-830
10. Dyck PJB, Dyck PJ (1999) Diabetic polyneuropathy. In: Dyck PJ, Thomas PK (eds) Diabetic neuropathy. W. B. Saunders, Philadelphia, pp 255-278
11. Dyck PJB, Engelstad J, Norell J, Dyck PJ (2000) Microvasculitis in non-diabetic lumbosacral radiculoplexus neuropathy (LSRPN): Similarity to the diabetic variety (DLSRPN). J Neuropath Exp Neurol 59:525-538
12. Dyck PJB, Norell JE, Dyck PJ (1999) Microvasculitis and ischemia in diabetic lumbosacral radiculoplexus neuropathy. Neurology 53:2113-2121
13. Dyck PJB, Norell JE, Dyck PJ (2001) Non-diabetic lumbosacral radiculoplexus neuropathy. Natural history, outcome and comparison with the diabetic variety. Brain 124:1197-1207
14. Empl M, Renaud S, Erne B, Fuhr P, Straube A, Schaeren-Wiemers N, Steck AJ (2001) TNF-alpha expression in painful and nonpainful neuropathies. Neurology 56(10):1371-1377
15. Evans BA, Stevens JC, Dyck PJ (1981) Lumbosacral plexus neuropathy. Neurology 31:1327-1330
16. Garland H (1955) Diabetic amyotrophy. Br Med J 2:1287-1296
17. Hall SM, Redford EJ, Smith KJ (2000) Tumour necrosis factor-alpha has few morphological effects within the dorsal columns of the spinal cord, in contrast to its effects in the peripheral nervous system. J Neuroimmunol 106(1-2):130-136
18. Haslbeck KM, Bierhaus A, Erwin S, Kirchner A, Nawroth P, Schlotzer U, Neundorfer B, Heuss D (2004) Receptor for advanced glycation endproduct (RAGE)-mediated nuclear factor-kappa B activation in vasculitic neuropathy. Muscle Nerve 29:853-860
19. Kawamura N, Schmeichel AM, Wang Y, Schmelzer JD, Low PA (2006) Multiple effects of hypothermia on inflammatory response following ischemia-reperfusion injury in experimental ischemic neuropathy. Exp Neurol 202(2):487-496
20. Kelkar PM, Masood M, Parry GJ (2000) Distinctive pathologic findings in proximal diabetic neuropathy (diabetic amyotrophy). Neurology 55(1):83-88
21. Lawrence T, Bebien M, Liu GY, Nizet V, Karin M (2005) IKKalpha limits macrophage NF-kappa B activation and contributes to the resolution of inflammation. Nature 434:1138-1143
22. Lindenlaub T, Sommer C (2003) Cytokines in sural nerve biopsies from inflammatory and non-inflammatory neuropathies. Acta Neuropathol (Berl) 105(6):593-602
23. Llewelyn JG, Thomas PK, King RHM (1998) Epineurial microvasculitis in proximal diabetic neuropathy. J Neurol 245(3):159-165
24. Mazzeo A, Aguennouz M, Messina C, Vita G (2004) Immunolocalization and activation of transcription factor nuclear factor kappa B in dysimmune neuropathies and familial amyloidotic polyneuropathy. Arch Neurol 61(7):1097-1102
25. Mitsui Y, Okamoto K, Martin DP, Schmelzer JD, Low PA (1999) The expression of proinflammatory cytokine mRNA in the sciatic-tibial nerve of ischemia-reperfusion injury. Brain Res 844(1-2):192-195
26. Nukada H, Lynch CD, McMorran PD (2002) Aggravated reperfusion injury in STZ-diabetic nerve. J Peripher Nerv Syst 7:37-43
27. Nukada H, McMorran PD, Shimizu J (2000) Acute inflammatory demyelination in reperfusion nerve injury. Ann Neurol 47(1):71-79
28. Oka N, Akiguchi I, Kawasaki T, Mizutani K, Satoi H, Kimura J (1998) Tumor necrosis factor-alpha in peripheral nerve lesions. Acta Neuropathol (Berl) 95(1):57-62
29. Oppenhheim JJ, Feldman M (2001) Introduction to the role of cytokines in innate and defense and adaptive immunity. In: Oppenhheim JJ, Feldman M (eds) Cytokine reference. Academic, New York, pp 3-20
30. Pascoe MK, Low PA, Windebank AJ, Litchy WJ (1997) Subacute diabetic proximal neuropathy. Mayo Clin Proc 72(12):1123-1132
31. Redford EJ, Hall SM, Smith KJ (1995) Vascular changes and demyelination induced by the intraneural injection of tumour necrosis factor. Brain 118(Pt 4):869-878
32. Said G, Lacroix C, Lozeron P, Ropert A, Plante V, Adams D (2003) Inflammatory vasculopathy in multifocal diabetic neuropathy. Brain 126:376-385
33. Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS Jr (1995) Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270:283-286
34. Siebert H, Bruck W (2003) The role of cytokines and adhesion molecules in axon degeneration after peripheral nerve axotomy: A study in different knockout mice. Brain Res 960(1-2):152-156
35. Tak PP, Firestein GS (2001) NF-kappaB: A key role in inflammatory diseases. J Clin Invest 107(1):7-11
36. Vougioukas VI, Roeske S, Michel U, Bruck W (1998) Wallerian degeneration in ICAM-1-deficient mice. Am J Pathol 152:241-249
37. Wang Y, Schmeichel AM, Iida H, Schmelzer JD, Low PA (2006) Enhanced inflammatory response via activation of NF-kappaB in acute experimental diabetic neuropathy subjected to ischemia-reperfusion injury. J Neurol Sci 247:47-52
38. Weinhold B, Ruther U (1997) Interleukin-6-dependent and -independent regulation of the human C-reactive protein gene. Biochem J 327(Pt 2):425-429