Clinical evaluation of the recombinant 38 kDa protein of Mycobacterium tuberculosis

Scandinavian Journal of Infectious Diseases

Volumn 40, Issue 2, 2008, Pages 121-126

  He, Xiu Yun ^a   Luo, Yong Ai ^b   Zhang, Xiao Gang ^a   Liu, Yuan Dong ^c   Wang, Zhong Yuan ^a   Luo, Feng Zhi ^d   Zhang, Ji Ping ^e   Wang, Qing ^f   Yan, Shi Ming ^g   Wang, Yan Jun ^a   Ma, Long Feng ^d   Guo, Jia ^d   Dong, Ya Jun ^d   Huang, Xiang Yu ^a   Zhuang, Yu Hui ^a  

^a GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c Shandong Center for Disease Control and Prevention   (China)

^d Shenyang Chest Hospital   (China)

^e Central Hospital of Taiyuan   (China)

^f Anhui Chest Hospital   (China)

^g Changchun Tuberculosis Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT PROTEIN; RECOMBINANT TRUNCATED 38 KDA PROTEIN; TUBERCULIN; UNCLASSIFIED DRUG;

ANTIGEN RECOGNITION; ARTICLE; BACTERIAL IMMUNITY; BLISTER; CLINICAL EVALUATION; CLINICAL TRIAL; CONTROLLED STUDY; CROSS REACTION; DIAGNOSTIC ACCURACY; DRUG SCREENING; FEMALE; HUMAN; IMMUNE ADHERENCE; IMMUNE RESPONSE; INFLAMMATION; MAJOR CLINICAL STUDY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PURPURIC RASH; SENSITIVITY AND SPECIFICITY; SKIN MANIFESTATION; SKIN TEST; TUBERCULIN TEST; TUBERCULOSIS;

ANIMALS; ANTIGENS, BACTERIAL; GUINEA PIGS; HUMANS; LIPOPROTEINS; MYCOBACTERIA, ATYPICAL; MYCOBACTERIUM BOVIS; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; TUBERCULIN; TUBERCULIN TEST; TUBERCULOSIS;

EID: 38149115419     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.1080/00365540701596011     Document Type: Article

References (23)

1. Studre, P., Dam, G Ten and Kochi, A. (1992) Tuberculosis: A global overview of the situation today. Bull W H O, 70, pp. 149-159.
2. Koli, A. (1991) The global tuberculosis situation and the new control strategy of the World Health Organization. Tuberculosis, 72, pp. 1-12.
3. Wang, XF, Zhang, XZ, Du, GZ, Wang, Zhang, Q. and Huang, J. (1995) Immune response of domestically made tuberculin. Chin J Biol, 1, pp. 40-42.
4. Grange, JM. (1987) Infection and disease due to environmental mycobacteria. Trans R Soc Trop Med Hyg, 81, pp. 179-182.
5. Jacobes, GG, Johnson, JL, Boom, WH, Wallis, RS, Whalen, CC and Ginsberg, AM. (1997) Tuberculosis vaccines: How close to human testing?. Tuberc Lung Dis, 78, pp. 159-169.
6. Cole, ST, Brosch, R., Parkhill, J., Garnier, T., Churcher, C. and Harris, D. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature, 393, pp. 537-544.
7. Jungblut, PR, Schaible, UE, Mollenkopf, HJ, Zimny-Arndt, U., Raupach, B. and Mattow, J. (1999) Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: Towards functional genomics of microbial pathogens. Mol Microbiol, 33, pp. 1103-1117.
8. Wilkinson, RJ, Haslov, K., Rappuoli, R., Giovannoni, F., Narayanan, PR and Desei, CR (1997) Evaluation of the recombinant 38-kilodalton antigen of Mycobacterium tuberculosis as a potential immunodiagnostic reagent. J Clin Microbiol, 33, pp. 553-557.
9. Elhay, MJ, Oettinger, T. and Andersen, P. (1998) Delayed-hypersensitivity responses to ESAT-6 and MPT64 from Mycobacterium tuberculosis in guinea pigs. Infect Immun, 66, pp. 3454-3456.
10. National Infection Survey Centre of China (2002) Reports on national epidemiology of tuberculosis in 2000. J Chin Antituberc Assoc, 24, pp. 65-108.
11. Braibant, M., Lefevre, P., de Wit, L., Peirs, O., Ooms, J. and Huygen, K. (1996) A Mycobacterium tuberculosis gene cluster encoding proteins of a phosphate transporter homologous to the Escherichia coli Pst system. Gene, 176, pp. 171-176.
12. Chang, ZY, Choudhary, R., Lathigra, R. and Quicho, FA. (1994) The immunodominant 38 kDa lipoprotein antigen of Mycobacterium tuberculosis is a phosphate-binding protein. J Biol Chem, 269, pp. 956-958.
13. Andersen, AB, Ljungqvist, L. and Olsen, M. (1990) Evidence that protein b of Mycobacterium tuberculosis is involved in phosphate metabolism. J Gen Microbiol, 136, pp. 477-480.
14. Haslov, K., Andersen, AB, Ljungqvist, L. and Bentzon, M. Weis (1990) Comparison of the immunological activity of 5 defined antigens from Mycobacterium tuberculosis in 7 inbred guinea pig strains: The 38 kDa antigen is immunodominant. Scand J Immunol, 31, pp. 503-514.
15. He, XY, Zhuang, YH, Zhang, XG, Xiong, ZH, Dong, EJ and Shi, YC. (2000) Immunological characteristics of the recombinant 38 kDa antigen from Mycobacterium tuberculosis. Chin J Tuberc Respir Dis, 23, pp. 485-488.
16. He, XY, Zhuang, YH, Zhang, XG, Xiong, ZH and Chang, ZY. (1999) 38 kDa protein of Mycobacterium tuberculosis is overexpressed in Escherichia coli. Chin J Tuberc Respir Dis, 22, pp. 138-141.
17. He, XY, Zhuang, YH, Zhang, XG, Dong, EJ, Xiong, ZH and Chang, ZY. (2000) Delayed-type hypersensitivity responses to recombinant mycobacterial antigen 38 kDa in guinea pigs sensitized with Mycobacterium tuberculosis. Chin J Tuberc Respir Dis, 23, pp. 161-163.
18. Vordermeier, HM, Harris, DP, Friscia, G., Roman, E., Surcel, HM and Moreno, C. (1992) T-cell repertoire in tuberculosis: Selective anergy to an immunodominant epitope of the 38 kDa antigen in patients with active disease. Eur J Immunol, 22, pp. 2631-2637.
19. Wilck, JT, Jensen, BN, Ravn, P., Andersen, AB and Haslov, K. (1996) Clinical evaluation of MPT-64 and MPT-59, 2 proteins secreted from Mycobacterium tuberculosis, for skin test reagents. Tuberc Lung Dis, 77, pp. 250-256.
20. Aggerbeck, H., McNair, J., Bassett, H., Cassidy, JP, Cstel, E. and Aggerbeck, H. (2003) Specific delayed-type hypersensitivity responses to ESAT-6 identify tuberculosis-infected cattle. J Clin Microbiol, 41, pp. 1856-1860.
21. Nakamura, RM, Einck, L., Velmonte, MA, Kawajiri, K., Ang, CF and Delasllagas, CE (2001) Detection of active tuberculosis by a MPB-64 transdermal patch: A field study. Scand J Infect Dis, 33, pp. 405-407.
22. Young, D., Kent, L., Rees, A., Lamb, J. and Ivanyi, J. (1986) Immunological activity of a 38-kilodalton protein purified from Mycobacterium tuberculosis. Infect Immun, 54, pp. 177-183.
23. Stanford, JL, Shield, MJ and Rook, GA. (1981) How environmental mycobacteria may predetermine the protective efficacy of BCG. Tubercle, 62, pp. 55-62.