Epidemiology of European community-associated methicillin-resistant Staphylococcus aureus clonal complex 80 type IV strains isolated in Denmark from 1993 to 2004

Journal of Clinical Microbiology

Volumn 46, Issue 1, 2008, Pages 62-68

  Larsen, A R ^a   Bocher S ^a   Stegger, M ^b   Goering, R ^b   Pallesen, L V ^a   Skov, R ^a  

^a STATENS SERUM INSTITUT   (Denmark)

^b CREIGHTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; STAPHYLOCOCCUS PROTEIN A;

ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CLONE; DENMARK; EPIDEMIC; EUROPE; GENE CASSETTE; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HOSPITAL INFECTION; HUMAN; MEC GENE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MIDDLE EAST; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SKIN INFECTION; SOFT TISSUE INFECTION; SOUTHERN EUROPE; SPA GENE; TRAVEL; UNITED STATES;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; CROSS INFECTION; DENMARK; DNA FINGERPRINTING; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; FAMILY HEALTH; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; METHICILLIN RESISTANCE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; SEQUENCE ANALYSIS, DNA; SOFT TISSUE INFECTIONS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCAL PROTEIN A; STAPHYLOCOCCAL SKIN INFECTIONS; STAPHYLOCOCCUS AUREUS; TRAVEL;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

EID: 38149113349     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.01381-07     Document Type: Article

References (50)

1. Aires de Sousa, M., C. Bartzavali, I. Spiliopoulou, I. S. Sanches, M. I. Crisostomo, and H. de Lencastre. 2003. Two international methicillin-resistant Staphylococcus aureus clones endemic in a university hospital in Patras, Greece. J. Clin. Microbiol. 41:2027-2032.
2. Aires de Sousa, M., and H. de Lencastre. 2003. Evolution of sporadic isolates of methicillin-resistant Staphylococcus aureus (MRSA) in hospitals and their similarities to isolates of community-acquired MRSA. J. Clin. Microbiol. 41:3806-3815.
3. Barrett, T. J., P. Gerner-Smidt, and B. Swaminathan. 2006. Interpretation of pulsed-field gel electrophoresis patterns in foodborne disease investigations and surveillance. Foodborne Pathog. Dis. 3:20-31.
4. Becker, K., A. W. Friedrich, G. Lubritz, M. Weilert, G. Peters, and C. von Eiff. 2003. Prevalence of genes encoding pyrogenic toxin superantigens and exfoliative toxins among strains of Staphylococcus aureus isolated from blood and nasal specimens. J. Clin. Microbiol. 41:1434-1439.
5. Berglund, C., P. Molling, L. Sjoberg, and B. Soderquist. 2005. Predominance of staphylococcal cassette chromosome mec (SCCmec) type IV among methicillin-resistant Staphylococcus aureus (MRSA) in a Swedish county and presence of unknown SCCmec types with Panton-Valentine leukocidin genes. Clin. Microbiol. Infect. 11:447-456.
6. Denis, O., A. Deplano, H. De Beenhouwer, M. Hallin, G. Huysmans, M. G. Garrino, Y. Glupczynski, X. Malaviolle, A. Vergison, and M. J. Struelens. 2005. Polyclonal emergence and importation of community-acquired methicillin-resistant Staphylococcus aureus strains harbouring Panton-Valentine leucocidin genes in Belgium. J. Antimicrob. Chemother. 56:1103-1106.
7. Dufour, P., Y. Gillet, M. Bes, G. Lina, F. Vandenesch, D. Floret, J. Etienne, and H. Richet. 2002. Community-acquired methicillin-resistant Staphylococcus aureus infections in France: emergence of a single clone that produces Panton-Valentine leukocidin. Clin. Infect. Dis. 35:819-824.
8. Faria, N. A., D. C. Oliveira, H. Westh, D. L. Monnet, A. R. Larsen, R. Skov, and H. de Lencastre. 2005. Epidemiology of emerging methicillin-resistant Staphylococcus aureus (MRSA) in Denmark: a nationwide study in a country with low prevalence of MRSA infection. J. Clin. Microbiol. 43:1836-1842.
9. Fossum, A. E., and G. Bukholm. 2006. Increased incidence of methicillin-resistant Staphylococcus aureus ST80, novel ST125 and SCCmecIV in the south-eastern part of Norway during a 12-year period. Clin. Microbiol. Infect. 12:627-633.
10. Gillet, Y., B. Issartel, P. Vanhems, J. C. Fournet, G. Lina, M. Bes, F. Vandenesch, Y. Piemont, N. Brousse, D. Floret, and J. Etienne. 2002. Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet 359:753-759.
11. Goering, R. V., D. Morrison, K. F. C. Cooper, Z. Al-Doori, G. F. S. Edwards, and C. G. Gemmell. 2004. Usefulness of mec-associated dru sequences in monitoring the spread of highly clonal epidemic methicillin-resistant Staphylococcus aureus isolates in Scotland, abstr. P582. Abstr. 14th Eur. Congr. Clin. Microbiol. Infect. Dis.
12. Hanssen, A. M., A. Fossum, J. Mikalsen, D. S. Halvorsen, G. Bukholm, and J. U. Sollid. 2005. Dissemination of community-acquired methicillin-resistant Staphylococcus aureus clones in northern Norway: sequence types 8 and 80 predominate. J. Clin. Microbiol. 43:2118-2124.
13. Harbarth, S., P. Francois, J. Schrenzel, C. Fankhauser-Rodriguez, S. Hugonnet, T. Koessler, A. Huyghe, and D. Pittet. 2005. Community-associated methicillin-resistant Staphylococcus aureus, Switzerland. Emerg. Infect. Dis. 11:962-965.
14. Harmsen, D., H. Claus, W. Witte, J. Rothganger, H. Claus, D. Turnwald, and U. Vogel. 2003. Typing of methicillin-resistant Staphylococcus aureus in a university hospital setting by using novel software for spa repeat determination and database management. J. Clin. Microbiol. 41:5442-5448.
15. Huijsdens, X. W., M. G. Santen-Verheuvel, E. Spalburg, M. E. Heck, G. N. Pluister, B. A. Eijkelkamp, A. J. de Neeling, and W. J. Wannet. 2006. Multiple cases of familial transmission of community-acquired methicillin-resistant Staphylococcus aureus. J. Clin. Microbiol. 44:2994-2996.
16. Huijsdens, X. W., A. M. van Lier, E. van Kregten, L. Verhoef, M. G. Santen-Verheuvel, E. Spalburg, and W. J. Wannet. 2006. Methicillin-resistant Staphylococcus aureus in Dutch soccer team. Emerg. Infect. Dis. 12:1584-1586.
17. Ito, T., X. X. Ma, F. Takeuchi, K. Okuma, H. Yuzawa, and K. Hiramatsu. 2004. Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC. Antimicrob. Agents Chemother. 48:2637-2651.
18. Jarraud, S., C. Mougel, J. Thioulouse, G. Lina, H. Meugnier, F. Forey, X. Nesme, J. Etienne, and F. Vandenesch. 2002. Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease. Infect. Immun. 70:631-641.
19. Johnson, L. B., A. Bhan, J. Pawlak, O. Manzor, and L. D. Saravolatz. 2003. Changing epidemiology of community-onset methicillin-resistant Staphylococcus aureus bacteremia. Infect. Control Hosp. Epidemiol. 24:431-435.
20. Klevens, R. M., M. A. Morrison, S. K. Fridkin, A. Reingold, S. Petit, K. Gershman, S. Ray, L. H. Harrison, R. Lynfield, G. Dumyati, J. M. Townes, A. S. Craig, G. Fosheim, L. K. McDougal, and F. C. Tenover. 2006. Community-associated methicillin-resistant Staphylococcus aureus and healthcare risk factors. Emerg. Infect. Dis. 12:1991-1993.
21. Kourbatova, E. V., J. S. Halvosa, M. D. King, S. M. Ray, N. White, and H. M. Blumberg. 2005. Emergence of community-associated methicillin-resistant Staphylococcus aureus USA 300 clone as a cause of health care-associated infections among patients with prosthetic joint infections. Am. J. Infect. Control 33:385-391.
22. Labandeira-Rey, M., F. Couzon, S. Boisset, E. L. Brown, M. Bes, Y. Benito, E. M. Barbu, V. Vazquez, M. Hook, J. Etienne, F. Vandenesch, and M. G. Bowden. 2007. Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science 315:1130-1133.
23. Lina, G., Y. Piemont, F. Godail-Gamot, M. Bes, M. O. Peter, V. Gauduchon, F. Vandenesch, and J. Etienne. 1999. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin. Infect. Dis. 29:1128-1132.
24. Linde, H., F. Wagenlehner, B. Strommenger, I. Drubel, J. Tanzer, U. Reischl, U. Raab, C. Holler, K. G. Naber, W. Witte, F. Hanses, B. Salzberger, and N. Lehn. 2005. Healthcare-associated outbreaks and community-acquired infections due to MRSA carrying the Panton-Valentine leucocidin gene in southeastern Germany. Eur. J. Clin. Microbiol. Infect. Dis. 24:419-422.
25. Maier, J., H. Melzl, U. Reischl, I. Drubel, W. Witte, N. Lehn, and H. Linde. 2005. Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus in Germany associated with travel or foreign family origin. Eur. J. Clin. Microbiol. Infect. Dis. 24:637-639.
26. McDougal, L. K., C. D. Steward, G. E. Killgore, J. M. Chaitram, S. K. McAllister, and F. C. Tenover. 2003. Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States: establishing a national database. J. Clin. Microbiol. 41:5113-5120.
27. Mehrotra, M., G. Wang, and W. M. Johnson. 2000. Multiplex PCR for detection of genes for Staphylococcus aureus enterotoxins, exfoliative toxins, toxic shock syndrome toxin 1, and methicillin resistance. J. Clin. Microbiol. 38:1032-1035.
28. Milheirico, C., D. C. Oliveira, and H. de Lencastre. 2007. Multiplex PCR strategy for subtyping the staphylococcal cassette chromosome mec type IV in methicillin-resistant Staphylococcus aureus: 'SCCmec IV multiplex.' J. Antimicrob. Chemother. 60:42-48.
29. Monecke, S., B. Berger-Bachi, G. Coombs, A. Holmes, I. Kay, A. Kearns, H. J. Linde, F. O'Brien, P. Slickers, and R. Ehricht. 2007. Comparative genomics and DNA array-based genotyping of pandemic Staphylococcus aureus strains encoding Panton-Valentine leukocidin. Clin. Microbiol. Infect. 13:236-249.
30. Monecke, S., P. Slickers, H. Hotzel, G. Richter-Huhn, M. Pohle, S. Weber, W. Witte, and R. Ehricht. 2006. Microarray-based characterisation of a Panton-Valentine leukocidin-positive community-acquired strain of methicillin-resistant Staphylococcus aureus. Clin. Microbiol. Infect. 12:718-728.
31. Murchan, S., M. E. Kaufmann, A. Deplano, R. De Ryck, M. Struelens, C. E. Zinn, V. Fussing, S. Salmenlinna, J. Vuopio-Varkila, N. El Solh, C. Cuny, W. Witte, P. T. Tassios, N. Legakis, W. van Leeuwen, A. van Belkum, A. Vindel, I. Laconcha, J. Garaizar, S. Haeggman, B. Olsson-Liljequist, U. Ransjo, G. Coombes, and B. Cookson. 2003. Harmonization of pulsed-field gel electrophoresis protocols for epidemiological typing of strains of methicillin-resistant Staphylococcus aureus: a single approach developed by conscnsus in 10 European laboratories and its application for tracing the spread of related strains. J. Clin. Microbiol. 41:1574-1585.
32. Nahvi, M. D., J. E. Fitzgibbon, J. F. John, and D. T. Dubin. 2001. Sequence analysis of dru regions from methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococcal isolates. Microb. Drug Resist. 7:1-12.
33. Okuma, K., K. Iwakawa, J. D. Turnidge, W. B. Grubb, J. M. Bell, F. G. O'Brien, G. W. Coombs, J. W. Pearman, F. C. Tenover, M. Kapi, C. Tiensasitorn, T. Ito, and K. Hiramatsu. 2002. Dissemination of new methicillin-resistant Staphylococcus aureus clones in the community. J. Clin. Microbiol. 40:4289-4294.
34. Oliveira, D. C., and H. de Lencastre. 2002. Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 46: 2155-2161.
35. O'Neill, A. J., A. R. Larsen, A. S. Henriksen, and I. Chopra. 2004. A fusidic acid-resistant epidemic strain of Staphylococcus aureus carries the fusB determinant, whereas fusA mutations are prevalent in other resistant isolates. Antimicrob. Agents Chemother. 48:3594-3597.
36. Salmenlinna, S., O. Lyytikainen, and J. Vuopio-Varkila. 2002. Community-acquired methicillin-resistant Staphylococcus aureus, Finland. Emerg. Infect. Dis. 8:602-607.
37. Seybold, U., H. M. Blumberg, S. J. Halvosa, E. Kourbatova, and M. D. King. 2005. Emergence of community-associated methicillin-resistant Staphylococcus aureus USA300 genotype in health care-associated bloodstream infections. J. Investig. Med. 53:S306.
38. Skov, R., N. Frimodt-Moller, and F. Espersen. 2001. Correlation of MIC methods and tentative interpretive criteria for disk diffusion susceptibility testing using NCCLS methodology for fusidic acid. Diagn. Microbiol. Infect. Dis. 40:111-116.
39. Skov, R. L., L. V. Pallesen, R. L. Poulsen, and F. Espersen. 1999. Evaluation of a new 3-h hybridization method for detecting the mecA gene in Staphylococcus aureus and comparison with existing genotypic and phenotypic susceptibility testing methods. J. Antimicrob. Chemother. 43:467-475.
40. 39a. Skov, R., C. S. Elsberg, J. K. Møller, B. Garhn-Hansen, H. C. Schønheyder, and H. Westh. 2000. Dissemination of a MRSA clone in Denmark, abstr. 221. Abstr. 9th Int. Symp. Staphylococci Staphylococcal Infect.
41. Tenover, F. C., L. K. McDougal, R. V. Goering, G. Killgore, S. J. Projan, J. B. Patel, and P. M. Dunman. 2006. Characterization of a strain of community-associated methicillin-resistant Staphylococcus aureus widely disseminated in the United States. J. Clin. Microbiol. 44:108-118.
42. Tristan, A., M. Bes, H. Meugnier, G. Lina, B. Bozdogan, P. Courvalin, M. E. Reverdy, M. C. Enright, F. Vandenesch, and J. Etienne. 2007. Global distribution of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus, 2006. Emerg. Infect. Dis. 13:594-600.
43. Urth, T., G. Juul, R. Skov, and H. C. Schonheyder. 2005. Spread of a methicillin-resistant Staphylococcus aureus ST80-IV clone in a Danish community. Infect. Control Hosp. Epidemiol. 26:144-149.
44. Vandenesch, F., T. Naimi, M. C. Enright, G. Lina, G. R. Nimmo, H. Heffernan, N. Liassine, M. Bes, T. Greenland, M. E. Reverdy, and J. Etienne. 2003. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg. Infect. Dis. 9:978-984.
45. Voyich, J. M., M. Otto, B. Mathema, K. R. Braughton, A. R. Whitney, D. Welty, R. D. Long, D. W. Dorward, D. J. Gardner, G. Lina, B. N. Kreiswirth, and F. R. DeLeo. 2006. Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? J. Infect. Dis. 194:1761-1770.
46. Wilkinson, J. D. 1998. Fusidic acid in dermatology. Br. J. Dermatol. 139(Suppl. 53):37-40.
47. Witte, W., C. Braulke, C. Cuny, B. Strommenger, G. Werner, D. Heuck, U. Jappe, C. Wendt, H. J. Linde, and D. Harmsen. 2005. Emergence of methicillin-resistant Staphylococcus aureus with Panton-Valentine leukocidin genes in central Europe. Eur. J. Clin. Microbiol. Infect. Dis. 24:1-5.
48. Witte, W., C. Cuny, B. Strommenger, C. Braulke, and D. Heuck. 2004. Emergence of a new community acquired MRSA strain in Germany. Euro. Surveill. 9:16-18.
49. Witte, W., G. Werner, and C. Cuny. 2001. Subtyping of MRSA isolates belonging to a widely disseminated clonal group by polymorphism of the dru sequences in mec-associated DNA. Int. J. Med. Microbiol. 291:57-62.
50. Yamasaki, O., A. Tristan, T. Yamaguchi, M. Sugai, G. Lina, M. Bes, F. Vandenesch, and J. Etienne. 2006. Distribution of the exfoliative toxin D gene in clinical Staphylococcus aureus isolates in France. Clin. Microbiol. Infect. 12:585-588.