Prospective evaluation of ondansetron for undifferentiated nausea and vomiting in the prehospital setting

Prehospital Emergency Care

Volumn 12, Issue 1, 2008, Pages 87-91

  Warden, Craig R ^a,b   Moreno, Raymond ^a   Daya, Mohamud ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Nausea; Ondansetron; Prehospital; Vomiting

Indexed keywords

ONDANSETRON; PLACEBO;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DRUG SCREENING; EMERGENCY HEALTH SERVICE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBIDITY; NAUSEA AND VOMITING; OUTCOME ASSESSMENT; WILCOXON SIGNED RANKS TEST;

ANTIEMETICS; EMERGENCY MEDICAL SERVICES; FEMALE; HUMANS; MALE; MIDDLE AGED; NAUSEA; ONDANSETRON; OREGON; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; VOMITING;

EID: 38149109786     PISSN: 10903127     EISSN: 15450066     Source Type: Journal    
DOI: 10.1080/10903120701707963     Document Type: Article

References (16)

1. Kober A, Fleischackl R, Scheck T, et al. A randomized controlled trial of oxygen for reducing nausea and vomiting during emergency transport of patients older than 60 years with minor trauma. Mayo Clin Proc. 2002;77(1):35-8.
2. Maio RF, Garrison HG, Spaite DW, et al. Emergency medical services outcomes project I (EMSOP I): prioritizing conditions for outcomes research. Ann Emerg Med. 1999;33(4):423-32.
3. Horowitz BZ, Bizovi K, Moreno R. Droperidol - behind the black box warning. Acad Emerg Med. 2002;9(6):615-8.
4. Ernst AA, Weiss SJ, Park S, Takakuwa KM, Diercks DB. Prochlorperazine versus promethazine for uncomplicated nausea and vomiting in the emergency department: a randomized, double-blind clinical trial. Ann Emerg Med. 2000;36(2):89-94.
5. Leman P. Utility of ondansetron in children with vomiting. Ann Emerg Med. 2002;40(3):366-7.
6. Reeves JJ, Shannon MW, Fleisher GR. Ondansetron decreases vomiting associated with acute gastroenteritis: a randomized, controlled trial. Pediatrics. 2002;109(4):e62.
7. Freedman SB, Adler M, Seshadri R, Powell EC. Oral ondansetron for gastroenteritis in a pediatric emergency department. NEJM. 2006;354(16):1698- 705.
8. Ramsook C, Sahagun-Carreon I, Kozinetz CA, Moro-Sutherland D. A randomized clinical trial comparing oral ondansetron with placebo in children with vomiting fromacute gastroenteritis. Ann Emerg Med. 2002;39(4):397-403.
9. Stork CM, Brown KM, Reilly TH, Secreti L, Brown LH. Emergency department treatment of viral gastritis using intravenous ondansetron or dexamethasone in children. Acad Emerg Med. 2006.
10. Holdgate A, Asha S, Craig J, Thompson J. Comparison of a verbal numeric rating scale with the visual analogue scale for the measurement of acute pain. Emerg Med (Fremantle, WA). 2003;15(5-6):441-6.
11. Lund I, Lundeberg T, Sandberg L, Budh CN, Kowalski J, Svensson E. Lack of interchangeability between visual analogue and verbal rating pain scales: a cross sectional description of pain etiology groups. BMC Med Res Method [electronic resource]. 2005;5:31.
12. Ohnhaus EE, Adler R. Methodological problems in the measurement of pain: a comparison between the verbal rating scale and the visual analogue scale. Pain. 1975;1(4):379-84.
13. Hendey GW, Donner NF, Fuller K. Clinically significant changes in nausea as measured on a visual analog scale. Ann Emerg Med. 2005;45(1):77-81.
14. Lombardi DG, Istwan NB, Rhea DJ, O'Brien JM, Barton JR. Measuring outpatient outcomes of emesis and nausea management in pregnant women. Manag Care. 2004;13(11):48-52.
15. Simpson KH, Hicks FM. Clinical pharmacokinetics of ondansetron. A review. J Pharm Pharmacol. 1996;48(8):774-81.
16. VanDenBerg CM, Kazmi Y, Stewart J, et al. Pharmacokinetics of three formulations of ondansetron hydrochloride in healthy volunteers: 24-mg oral tablet, rectal suppository, and i.v. infusion. Am J Health Syst Pharm. 2000;57(11):1046-50.