Fever and sickness behavior during an opportunistic infection in a free-living antelope, the greater kudu (Tragelaphus strepsiceros)

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 294, Issue 1, 2008, Pages

  Hetem, Robyn S ^a   Mitchell, Duncan ^a   Maloney, Shane K ^a,b   Meyer, Leith C R ^a   Fick, Linda G ^a   Kerley, Graham I H ^c   Fuller, Andrea ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c NELSON MANDELA METROPOLITAN UNIVERSITY   (South Africa)

Author keywords

Selective brain cooling; Thermoregulation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTELOPE; ARTICLE; BACTERIAL PNEUMONIA; BODY TEMPERATURE; CLIMATE; CONTROLLED STUDY; FEMALE; FEVER; HEAT LOSS; ILLNESS BEHAVIOR; NONHUMAN; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; THERMOMETER; THERMOREGULATION; TRAGELAPHUS STREPSICEROS; VASOCONSTRICTION;

ANIMALS; ANIMALS, WILD; ANTELOPES; BACTERIAL INFECTIONS; BEHAVIOR, ANIMAL; BODY TEMPERATURE; BODY TEMPERATURE REGULATION; BRAIN; CLIMATE; FEMALE; FEVER; OPPORTUNISTIC INFECTIONS; SOUTH AFRICA; STRESS;

EID: 38149085902     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00570.2007     Document Type: Article

References (57)

1. Aubert A. Sickness and behaviour in animals: a motivational perspective. Neurosci Biobehav Rev 23: 1029-1036, 1999.
2. Aubert A, Goodall G, Dantzer R, Gheusi G. Differential effects of lipopolysaccharide on pup retrieving and nest building in lactating mice. Brain Behav Immun 11: 107-118, 1997.
3. Banet M. Fever and survival in the rat. Pflügers Arch 381: 35-38, 1979.
4. Banet M. Fever and survival in the rat. Metabolic versus temperature response. Cell Mol Life Sci 37: 1302-1304, 1981.
5. Baracos VE, Whitmore WT, Gale R. The metabolic cost of fever. Can J Physiol Pharmacol 65: 1248-1254, 1987.
6. Chesy G, Kadziela W, Lachowski A, Caputa M, Kozak W, Wieczor H. Pyrogen fever and selective brain cooling in the ox. In: Contributions to Thermal Physiology, edited by Szelenyi Z, and Szekely M. Oxford: Pergamon Press, 1980, p. 197-199.
7. Dantzer R. Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity. Eur J Pharmacol 500: 399-411, 2004.
8. Demas GE, Chefer V, Talan MI, Nelson RJ. Metabolic costs of mounting an antigen-stimulated immune response in adult and aged C57BL/6J mice. Am J Physiol Regul Integr Comp Physiol 273: R1631-R1637, 1997.
9. Elliot SL, Blanford S, Thomas MB. Host-pathogen interactions in a varying environment: temperature, behavioural fever and fitness. Proc Biol Sci 269: 1599-1607, 2002.
10. Ewald PW. Evolutionary biology and the treatment of signs and symptoms of infectious disease. J Theor Biol 86: 169-176, 1980.
11. Fabricius C, Mentis MT. Modeling the habitat relations of Kudu in arid Savanna. S Afr J Sci 88: 280-284, 1992.
12. Fuller A, Kamerman PR, Maloney SK, Matthee A, Mitchell G, Mitchell D. A year in the thermal life of a free-ranging herd of springbok Antidorcas marsupialis. J Exp Biol 208: 2855-2864, 2005.
13. Fuller A, Meyer LCR, Mitchell D, Maloney SK. Dehydration increases the magnitude of selective brain cooling independently of core temperature in sheep. Am J Physiol Regul Integr Comp Physiol 293: R438-R446, 2007.
14. Gannon WL, Sikes RS. And the Animal Care and Use Committee of the American Society of Mammalogists. Guidelines of the American Society of Mammalogists for the use of wild mammals in research. J Mammal 88: 809-823, 2007.
15. Gordon CJ. 24-hour control of body temperature in the rat. II: Diisopropyl fluorophosphate-induced hypothermia and hyperthermia. Pharmacol Biochem Behav 49: 747-754, 1994.
16. Gourine AV, Rudolph K, Tesfaigzi J, Kluger MJ. Role of hypothalamic interleukin-1β in fever induced by cecal ligation and puncture in rats. Am J Physiol Regul Integr Comp Physiol 275: R754-R761, 1998.
17. Hales JR, Bennett JW, Baird JA, Fawcett AA. Thermoregulatory effects of prostaglandins E1, E2, F1 and F2 in the sheep. Pflügers Arch 339: 125-133, 1973.
18. Hart BL. Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 12: 123-137, 1988.
19. Henley SR. Habitat Suitability and Modelling for Ungulates in the Thicket Biome, Eastern Cape (PhD thesis). University of Port Elizabeth, Eastern Cape, South Africa, 2001.
20. Hetem RS, Maloney SK, Fuller A, Meyer LCR, Mitchell D. Validation of a biotelemetric technique, using ambulatory miniature black globe thermometers, to quantify thermoregulatory behaviour in ungulates. J Exp Zool 307A: 342-356, 2007.
21. Hori T, Harada Y. The effects of ambient and hypothalamic temperatures on the hyperthermic responses to prostaglandins E1 and E2. Pflügers Arch 350: 123-134, 1974.
22. IUPS Thermal Commission. Glossary of terms for thermal physiology. J Therm Biol 28: 75-106, 2003.
23. Johnson RW. The concept of sickness behavior: a brief chronological account of four key discoveries. Vet Immunol Immunopathol 87: 443-450, 2002.
24. Kamerman PR, Fuller A, Faurie AS, Mitchell G, Mitchell D. Body temperature patterns during natural fevers in a herd of free-ranging impala (Aepyceros melampus). Vet Rec 149: 26-27, 2001.
25. Kluger MJ. The evolution and adaptive value of fever. Am Sci 66: 38-43, 1978.
26. Kluger MJ. Fever: role of pyrogens and cryogens. Physiol Rev 71: 93-127, 1991.
27. Kluger MJ. Is fever beneficial? Yale J Biol Med 59: 89-95, 1986.
28. Kluger MJ. Phylogeny of fever. Fed Proc 38: 30-34, 1979.
29. Kluger MJ, Kozak W, Conn CA, Leon LR, Soszynski D. The adaptive value of fever. Infect Dis Clin North Am 10: 1-20, 1996.
30. Kluger MJ, Kozak W, Conn CA, Leon LR, Soszynski D. Role of fever in disease. Ann NY Acad Sci 856: 224-233, 1998.
31. Konsman JP, Parnet P, Dantzer R. Cytokine-induced sickness behaviour: mechanisms and implications. Trends Neurosci 25: 154-159, 2002.
32. Kozak W, Conn CA, Kluger MJ. Lipopolysaccharide induces fever and depresses locomotor activity in unrestrained mice. Am J Physiol Regul Integr Comp Physiol 266: R125-R135, 1994.
33. Kuhnen G. Selective brain cooling during fever. In: Thermal Balance in Health and Disease: Advances in Pharmacological Sciences, edited by Zeisberger E, Schonbaum E, and Lomax P. Basel: Birkhauser, Verlag 1994, p. 353-358.
34. Kuhnen G. Selective brain cooling reduces respiratory water loss during heat stress. Comp Biochem Physiol A 118: 891-895, 1997.
35. Kuhnen G, Jessen C. Effects of selective brain cooling on mechanisms of respiratory heat loss. Pflügers Arch 421: 204-208, 1992.
36. Kuhnen G, Jessen C. Threshold and slope of selective brain cooling. Pflügers Arch 418: 176-183, 1991.
37. Laburn HP, Mitchell D, Mitchell G, Saffy K. Effects of tracheostomy breathing on brain and body temperatures in hyperthermic sheep. J Physiol 406: 331-344, 1988.
38. LeGrand EK, Brown CC. Darwinian medicine: applications of evolutionary biology for veterinarians. Can Vet J 43: 556-559, 2002.
39. Lell B, Brandts CH, Graninger W, Kremsner PG. The circadian rhythm of body temperature is preserved during malarial fever. Wien Klin Wochenschr 112: 1014-1015, 2000.
40. Lochmiller RL, Deerenberg C. Trade-offs in evolutionary immunology: just what is the cost of immunity? Oikos 88: 87-98, 2000.
41. Luker FI, Mitchell D, Laburn HP. Fever and motor activity in rats following day and night injections of Staphylococcus aureus cell walls. Am J Physiol Regul Integr Comp Physiol 279: R610-R616, 2000.
42. Mitchell D, Maloney SK, Jessen C, Laburn HP, Kamerman PR, Mitchell G, Fuller A. Adaptive heterothermy and selective brain cooling in arid-zone mammals. Comp Biochem Physiol B 131: 571-585, 2002.
43. Morrow JD, Opp MR. Diurnal variation of lipopolysaccharide-induced alterations in sleep and body temperature of interleukin-6-deficient mice. Brain Behav Immun 19: 40-51, 2005.
44. Mphahlele NR, Fuller A, Roth J, Kamerman PR. Body temperature, behavior, and plasma cortisol changes induced by chronic infusion of Staphylococcus aureus in goats. Am J Physiol Regul Integr Comp Physiol 287: R863-R869, 2004.
45. Murakami DM, Horwitz BA, Fuller CA. Circadian rhythms of temperature and activity in obese and lean Zucker rats. Am J Physiol Regul Integr Comp Physiol 269: R1038-R1043, 1995.
46. Musher DM, Fainstein V, Young EJ, Pruett TL. Fever patterns. Their lack of clinical significance. Arch Intern Med 139: 1225-1228, 1979.
47. O'Reilly B, Vander AJ, Kluger MJ. Effects of chronic infusion of lipopolysaccharide on food intake and body temperature of the rat. Physiol Behav 42: 287-291, 1988.
48. Owen-Ashley NT, Turner M, Hahn TP, Wingfield JC. Hormonal, behavioral, and thermoregulatory responses to bacterial lipopolysaccharide in captive and free-living white-crowned sparrows (Zonotrichia leucophrys gambelii). Horm Behav 49: 15-29, 2006.
49. Owen-Ashley NT, Wingfield JC. Seasonal modulation of sickness behavior in free-living northwestern song sparrows (Melospiza melodia morphna). J Exp Biol 209: 3062-3070, 2006.
50. Robertshaw D. Mechanisms for the control of respiratory evaporative heat loss in panting animals. J Appl Physiol 101: 664-668, 2006.
51. Skinner JD, Chimimba CT. The Mammals of the Southern African Subregion. Cape Town, South Africa: Cambridge University Press, 2005.
52. Stitt JT. Prostaglandin E1 fever induced in rabbits. J Physiol 232: 163-179, 1973.
53. Szelenyi Z, Hummel Z, Szekely M, Petervari E. CCK-8 and PGE1: central effects on circadian body temperature and activity rhythms in rats. Physiol Behav 81: 615-621, 2004.
54. Tegowska E, Narebski J. Absence of selective brain cooling in pyrogen-induced fever in rabbits. Acta Physiol Pol 36: 256-266, 1985.
55. Vlok J, Euston-Brown D, Cowling R. Acocks' Valley Bushveld 50 years on: new perspectives on the delimitation, characterisation and origin of Subtropical Thicket vegetation. SA J Bot 69: 27-51 2003.
56. Wingfield JC. Control of behavioural strategies for capricious environments. Anim Behav 66: 807-816, 2003.
57. Yirmiya R, Avitsur R, Donchin O, Cohen E. Interleukin-1 inhibits sexual behavior in female but not in male rats. Brain Behav Immun 9: 220-233, 1995.