Comments regarding the recent OAST article [14]

Stroke

Volumn 39, Issue 1, 2008, Pages

  Miller, Scott W ^a   Palesch, Yuko Y ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISUFENTON SODIUM; PLACEBO; ANTIOXIDANT; BENZENESULFONIC ACID DERIVATIVE;

ACUTE DISEASE; ANALYSIS OF VARIANCE; BRAIN ISCHEMIA; CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; DRUG EFFECT; HUMAN; LETTER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RANKIN SCALE; SCORING SYSTEM; STATISTICAL ANALYSIS; STROKE; TREATMENT OUTCOME; HOSPITALIZATION; NOTE; OUTCOME ASSESSMENT; RISK; STATISTICAL MODEL;

ANALYSIS OF VARIANCE; ANTIOXIDANTS; BENZENESULFONATES; HUMANS; MODELS, STATISTICAL; ODDS RATIO; OUTCOME ASSESSMENT (HEALTH CARE); SEVERITY OF ILLNESS INDEX; STROKE; TREATMENT OUTCOME;

EID: 38149078283     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.107.500355     Document Type: Letter

References (5)

1. The Optimising Analysis of Stroke Trials (OAST) Collaboration. Can we improve the statistical analysis of stroke trials? Stroke. 2007;38:1911-1915.
2. Hollander M, Wolfe DA. Nonparametric Statistical Methods. Wiley, 1999.
3. Lees KR, Zivin JA, Ashwood T, Davalos A, Davis SM, Diner H-C, Grotta J, Lyden P, Shuaib A, Hardemark H-G, Wasiewski WW; for the Stroke-Acute Ischemic NXY Treatment (SAINT I) Trial Investigators. NXY-059 for acute ischemic stroke. N Engl J Med. 2006;354:588-600.
4. Shuaib A, Lees KR, Lyden P, Grotta J, Davalos A, Davis SM, Diener HC, Ashwood T, Wasiewski WW, Emeribe U; SAINT II trial investigators. NXY-059 for the treatment of acute ischemic stroke. N Engl J Med. 2007;357:562-571.
5. Koziol JA, Feng AC. On the analysis and interpretation of outcome measures in stroke clinical trials: lessons from the SAINT I study of NXY-059 for acute ischemic stroke. Stroke. 2006;37:2644-2647.