Calcium/calmodulin-dependent protein kinase II supports morphine antinociceptive tolerance by phosphorylation of glycosylated phosducin-like protein

Neuropharmacology

Volumn 54, Issue 2, 2008, Pages 319-330

  Sánchez Blázquez, Pilar ^a   Rodríguez Muñoz, María ^a   Montero, Carlos ^a   de la Torre Madrid, Elena ^a   Garzón, Javier ^a  

^a INSTITUTO CAJAL   (Spain)

Author keywords

CaMKII; G dimers; G proteins; Morphine tolerance; Opioid receptors; Phosducin like protein

Indexed keywords

DIMER; G PROTEIN COUPLED RECEPTOR KINASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN; MORPHINE; MU OPIATE RECEPTOR; PEPTIDES AND PROTEINS; PHOSDUCIN LIKE PROTEIN 1; PROTEIN 14 3 3; PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN SUBUNIT; SERINE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENZYME INHIBITION; GLYCOSYLATION; MALE; MOUSE; NOCICEPTION; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; WESTERN BLOTTING;

ANALGESICS, OPIOID; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARRIER PROTEINS; DRUG TOLERANCE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GLYCOSYLATION; IMMUNOGLOBULIN G; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MORPHINE; NERVE TISSUE PROTEINS; PAIN MEASUREMENT; PHOSPHORYLATION; REACTION TIME; RECEPTORS, OPIOID, MU; SERINE; SIGNAL TRANSDUCTION; SYNAPTOSOMES;

EID: 38149077089     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2007.10.002     Document Type: Article

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