Urine protein profile of IgA nephropathy patients may predict the response to ACE-inhibitor therapy

Proteomics

Volumn 8, Issue 1, 2008, Pages 206-216

  Rocchetti, Maria Teresa ^a   Centra, Marta ^a   Papale, Massimo ^a   Bortone, Grazia ^a   Palermo, Carmen ^a   Centonze, Diego ^a   Ranieri, Elena ^a   Di Paolo, Salvatore ^a   Gesualdo, Loreto ^a  

^a UNIVERSITY OF FOGGIA   (Italy)

Author keywords

ACE inhibitors; IgA nephropathy; Nano HPLC ESI MS MS; Two dimensional gel electrophoresis; Urinary proteome

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IMMUNOGLOBULIN A; INTER ALPHA TRYPSIN INHIBITOR; KININOGEN; PREALBUMIN; PROTEOME;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG RESPONSE; ELECTRON SPIN RESONANCE; FEMALE; FOLLOW UP; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY BIOPSY; KIDNEY FUNCTION; MALE; MASS SPECTROMETER; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEINURIA; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TREATMENT RESPONSE; URINARY EXCRETION;

ADULT; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; GLOMERULONEPHRITIS, IGA; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROTEIN ARRAY ANALYSIS; PROTEINURIA; PROTEOME; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 38149066050     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200700492     Document Type: Article

References (26)

1. Barratt, J., Feehally, J., IgA nephropathy. J. Am. Soc. Nephrol. 2005, 16, 2088-2097.
2. Appel, G. B., Waldman, M., The IgA nephropathy treatment dilemma. Kidney Int. 2006, 69, 1939-1944.
3. D'Amico, G., Colasanti, G., Barbiano di Belgioioso, G., Fellin, G. et al., Long-term follow-up of IgA mesangial nephropathy: Clinico-histological study in 374 patients. Semin. Nephrol. 1987, 7, 355-358.
4. Schena, F. P., Gesualdo, L., Markers of progression in IgA nephropathy. J. Nephrol. 2001, 14, 554-574.
5. Manno, C., Strippoli, G. F., D'Altri, C., Torres, D. et al., A novel simpler histological classification for renal survival in IgA nephropathy: A retrospective study. Am. J. Kidney Dis. 2007, 49, 763-775.
6. Wakai, K., Kawamura, T., Endoh, M., Kojima, M. et al., A scoring system to predict renal outcome in IgA nephropathy: From a nationwide prospective study. Nephrol. Dial. Transplant. 2006, 21, 2800-2808.
7. Klein, J. B., Thongboonkerd, V., Overview of proteomics, in: Thongboonkerd, V., Klein, J. B. (Eds.), Proteomics in Nephrology, Contrib. Nephrol., Basel, Karger 2004, 141, pp. 1-10.
8. Haubitz, M., Wittke, S., Weissinger, E. M., Waiden, M. et al., Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy. Kidney Int. 2005, 67, 2313-2320.
9. Park, M. R., Wang, E. H., Jin, D. C., Cha, J. et al., Establishment of a 2-D human urinary proteomic map in IgA nephropathy. Proteomics 2006, 6, 1066-1076.
10. Yokota, H., Hiramoto, M., Okada, H., Kanno, Y. et al., Absence of increased α 1-microglobulin in IgA nephropathy proteinuria. Mol. Cell. Proteomics 2007, 6, 738-744.
11. Thongboonkerd, V., McLeish, K. R., Arthur, J. M., Klein, J. B. et al., Proteomic analysis of normal urinary proteins isolated by acetone precipitation or ultracentrifugation. Kidney Int. 2002, 62, 1461-1469.
12. Shevchenko, A., Wilm, M., Vorm, O., Mann, M. et al., Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 1996, 68, 850-858.
13. Thongboonkerd, V., Klein, J. B., Jevans, A. W., McLeish, K. R., Urinary proteomics and biomarker discovery for glomerular diseases. Contrib. Nephrol. 2004, 141, 292-307.
14. Sharma, K., Lee, S., Han, S., Lee, S. et al., Two-dimensional fluorescence difference gel electrophoresis analysis of the urine proteome in human diabetic nephropathy. Proteomics 2005, 5, 2648-2655.
15. Candiano, G., Musante, L., Bruschi, M., Petretto, A. et al., Repetitive fragmentation products of albumin and alpha-1-antitrypsin in glomerular diseases associated with nephrotic syndrome. J. Am. Soc. Nephrol. 2006, 17, 3139-3148.
16. Bazzi, C., D'Amico, G., The urinary excretion of IgG and alpha1-microglobulin predicts renal outcome and identifies patients deserving treatment in membranous nephropathy. Kidney Int. 2002, 61, 2276.
17. Bazzi, C., Petrini, C., Rizza, V., Arrigo, G. et al., Urinary excretion of IgG and alpha(1)-microglobulin predicts clinical course better than the extent of proteinuria in membranous nephropathy. Am. J. Kidney Dis. 2001, 38, 240-248.
18. Sousa, M. M., Norden, A. G., Jacobsen, C., Willnow, T. E. et al., Evidence for the role of megalin in renal uptake of transthyretin. J. Biol. Chem. 2000, 275, 38176-38181.
19. Piwon, N., Gunther, W., Schwake, M., Bosl, M. R., Jentsch, T. J., ClC-5 Cl-channel disruption impairs endocytosis in a mouse model for Dent's disease. Nature 2000, 408, 369-373.
20. Tojo, A., Onorato, M. L., Ha, H., Kurihara, H. et al., Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats. Histochem. Cell Biol. 2001, 116, 269-276.
21. Obermuller, N., Kranzlin, B., Blum, W. F., Gretz, N., Witzgall, R., An endocytosis defect as a possible cause of proteinuria in polycystic kidney disease. Am. J. Physiol. Renal Physiol. 2001, 280, F244-F253.
22. Norden, A. G., Lapsley, M., Igarashi, T., Kelleher, C. L. et al., Urinary megalin deficiency implicates abnormal tubular endocytic function in Fanconi syndrome. J. Am. Soc. Nephrol. 2002, 13, 125-133.
23. Heitner, J. C., Koy, C., Kreutzer, M., Gerber, B. et al., Differentiation of HELLP patients from healthy pregnant women by proteome analysis - On the way towards a clinical marker set. J. Chromatogr. B 2006, 840, 10-19.
24. Weinberg, M. S., Azar, P., Trebbin, W. M., Solomon, R. J., The role of urinary kininogen in the regulation of kinin generation. Kidney Int. 1985, 28, 975-981.
25. Chao, J., Chao, L., Kallikrein-kinin in stroke, cardiovascular and renal disease. Exp. Physiol. 2005, 90, 291-298.
26. Lee, H. S., Choi, Y., Lee, J. S., Yu, B. H., Koh, H. I., Ultrastructural changes in IgA nephropathy in relation to histologic and clinical data. Kidney Int. 1989, 35, 880-886.