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Volumn 8, Issue 2, 2008, Pages 288-297

In vitro and in vivo prevention of human CD8+ CTL-mediated xenocytotoxicity by pig c-FLIP expression in porcine endothelial cells

Author keywords

Apoptosis; Cellular FLICE like inhibitory protein (c FLIP); Fas antigen; Human CTL; Xenotransplantation

Indexed keywords

CASPASE 10; CASPASE 3; CASPASE 8; CD8 ANTIGEN; FAS LIGAND; FLICE INHIBITORY PROTEIN;

EID: 38149051534     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2007.02077.x     Document Type: Article
Times cited : (8)

References (51)
  • 1
    • 0023683392 scopus 로고
    • Xenogeneic transplantation. a review
    • Auchincloss H Jr. Xenogeneic transplantation. A review. Transplantation 1988 46 : 1 20.
    • (1988) Transplantation , vol.46 , pp. 1-20
    • Auchincloss Jr., H.1
  • 2
    • 0026352644 scopus 로고
    • The barrier to xenotransplantation
    • Platt JL, Bach FH. The barrier to xenotransplantation. Transplantation 1991 52 : 937 947.
    • (1991) Transplantation , vol.52 , pp. 937-947
    • Platt, J.L.1    Bach, F.H.2
  • 3
    • 0026623093 scopus 로고
    • Identification of carbohydrate structures that bind human antiporcine antibodies: Implications for discordant xenografting in humans
    • Good AH, Cooper DKC, Malcolm AJ et al. Identification of carbohydrate structures that bind human antiporcine antibodies: Implications for discordant xenografting in humans. Transplant Proc 1992 24 : 559 562.
    • (1992) Transplant Proc , vol.24 , pp. 559-562
    • Good, A.H.1    Cooper, D.K.C.2    Malcolm, A.J.3
  • 4
    • 0027508081 scopus 로고
    • Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: A major obstacle for xenotransplantation in humans
    • Galili U. Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: A major obstacle for xenotransplantation in humans. Immunol Today 1993 14 : 480 482.
    • (1993) Immunol Today , vol.14 , pp. 480-482
    • Galili, U.1
  • 5
    • 0027517325 scopus 로고
    • Anti-pig IgM antibodies in human serum react predominantly with Gal(α1-3)Gal epitopes
    • Sandrin MS, Vaughan HA, Dabkowsky PL, McKenzie IFC. Anti-pig IgM antibodies in human serum react predominantly with Gal(α1-3)Gal epitopes. Proc Natl Acad Sci USA 1993 90 : 11391 11395.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11391-11395
    • Sandrin, M.S.1    Vaughan, H.A.2    Dabkowsky, P.L.3    McKenzie, I.F.C.4
  • 6
    • 0033975551 scopus 로고    scopus 로고
    • Differential immune responses to α-gal epitopes on xenografts and allografts: Implications for accommodation in xenotransplantation
    • Tanemura M, Yin D, Chong AS, Galili U. Differential immune responses to α-gal epitopes on xenografts and allografts: Implications for accommodation in xenotransplantation. J Clin Invest 2000 105 : 301 310.
    • (2000) J Clin Invest , vol.105 , pp. 301-310
    • Tanemura, M.1    Yin, D.2    Chong, A.S.3    Galili, U.4
  • 7
    • 0037039771 scopus 로고    scopus 로고
    • Production of α-1,3-Galactosyltransferase knockout pigs by nuclear transfer cloning
    • Lai L, Kolber-Simonds D, Park KW et al. Production of α-1,3-Galactosyltransferase knockout pigs by nuclear transfer cloning. Science 2002 295 : 1089 1092.
    • (2002) Science , vol.295 , pp. 1089-1092
    • Lai, L.1    Kolber-Simonds, D.2    Park, K.W.3
  • 8
    • 0347367029 scopus 로고    scopus 로고
    • Production of α1,3-Galactosyltransferase-deficient pigs
    • Phelps CJ, Koike C, Vaught TD et al. Production of α1,3- Galactosyltransferase-deficient pigs. Science 2003 299 : 411 414.
    • (2003) Science , vol.299 , pp. 411-414
    • Phelps, C.J.1    Koike, C.2    Vaught, T.D.3
  • 9
    • 13444282227 scopus 로고    scopus 로고
    • Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: Initial experience
    • Kuwaki K, Tseng YL, Dor FJMF et al. Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: Initial experience. Nat Med 2005 11 : 29 31.
    • (2005) Nat Med , vol.11 , pp. 29-31
    • Kuwaki, K.1    Tseng, Y.L.2    Fjmf, D.3
  • 10
    • 13444269248 scopus 로고    scopus 로고
    • Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue
    • Yamada K, Yazawa K, Shimizu A et al. Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3- galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue. Nat Med 2005 11 : 32 34.
    • (2005) Nat Med , vol.11 , pp. 32-34
    • Yamada, K.1    Yazawa, K.2    Shimizu, A.3
  • 12
    • 0031965879 scopus 로고    scopus 로고
    • Role of natural killer cells, macrophages, and accessory molecule interactions in the rejection of pig-to-primate xenografts beyond the hyperacute period
    • Itescu S, Kwiatkowski P, Artrip JH et al. Role of natural killer cells, macrophages, and accessory molecule interactions in the rejection of pig-to-primate xenografts beyond the hyperacute period. Hum Immunol 1998 59 : 275 286.
    • (1998) Hum Immunol , vol.59 , pp. 275-286
    • Itescu, S.1    Kwiatkowski, P.2    Artrip, J.H.3
  • 13
    • 0033485755 scopus 로고    scopus 로고
    • HLA-E and HLA-G expression on porcine endothelial cells inhibit xenoreactive human NK cells through CD94/NKG2-dependent and independent pathways
    • Sasaki H, Xu XC, Mohanakumar T. HLA-E and HLA-G expression on porcine endothelial cells inhibit xenoreactive human NK cells through CD94/NKG2-dependent and independent pathways. J Immunol 1999 163 : 6301 6305.
    • (1999) J Immunol , vol.163 , pp. 6301-6305
    • Sasaki, H.1    Xu, X.C.2    Mohanakumar, T.3
  • 14
    • 0028406899 scopus 로고
    • Porcine aortic endothelialcells activated human T cells: Direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28
    • Murray AG, Khodadoust MM, Pober JS, Bothwell ALM. Porcine aortic endothelialcells activated human T cells: Direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28. Immunity 1994 1 : 57 63.
    • (1994) Immunity , vol.1 , pp. 57-63
    • Murray, A.G.1    Khodadoust, M.M.2    Pober, J.S.3    Bothwell, A.L.M.4
  • 17
    • 0035576228 scopus 로고    scopus 로고
    • Without CD4 help, CD8 rejection of pig xenografts requires CD28 costimulation but not perforin killing
    • Zhan Y, Brady JL, Sutherland RM, Lew AM. Without CD4 help, CD8 rejection of pig xenografts requires CD28 costimulation but not perforin killing. J Immunol 2001 167 : 6279 6285.
    • (2001) J Immunol , vol.167 , pp. 6279-6285
    • Zhan, Y.1    Brady, J.L.2    Sutherland, R.M.3    Lew, A.M.4
  • 19
    • 33645065134 scopus 로고    scopus 로고
    • Significant inhibition of human CD8(+) cytotoxic T lymphocyte-mediated xenocytotoxicity by overexpression of the human decoy Fas antigen
    • Kawamoto K, Tanemura M, Nishida T et al. Significant inhibition of human CD8(+) cytotoxic T lymphocyte-mediated xenocytotoxicity by overexpression of the human decoy Fas antigen. Transplantation 2006 81 : 789 796.
    • (2006) Transplantation , vol.81 , pp. 789-796
    • Kawamoto, K.1    Tanemura, M.2    Nishida, T.3
  • 20
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN, Korsmeyer SJ. Cell death: Critical control points. Cell 2004 116 : 205 219.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 21
    • 0033575255 scopus 로고    scopus 로고
    • Suicidal tendencies: Apoptotic cell death by caspase family proteinases
    • Wolf BB, Green DR. Suicidal tendencies: Apoptotic cell death by caspase family proteinases. J Biol Chem 1999 274 : 20049 20052.
    • (1999) J Biol Chem , vol.274 , pp. 20049-20052
    • Wolf, B.B.1    Green, D.R.2
  • 22
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik Y. Caspases: Enemies within. Science 1998 281 : 1312 1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 23
    • 0030800070 scopus 로고    scopus 로고
    • Inhibition of death receptor signals by cellular FLIP
    • Irmler M, Thome M, Hahne M et al. Inhibition of death receptor signals by cellular FLIP. Nature 1997 388 : 190 195.
    • (1997) Nature , vol.388 , pp. 190-195
    • Irmler, M.1    Thome, M.2    Hahne, M.3
  • 24
    • 0030810981 scopus 로고    scopus 로고
    • FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis
    • Srinivasula SM, Ahmad M, Ottilie S et al. FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis. J Biol Chem 1997 272 : 18542 18545.
    • (1997) J Biol Chem , vol.272 , pp. 18542-18545
    • Srinivasula, S.M.1    Ahmad, M.2    Ottilie, S.3
  • 25
    • 0030841911 scopus 로고    scopus 로고
    • I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
    • Hu S, Vincenz C, Ni J, Gentz R, Dixit VM. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J Biol Chem 1997 272 : 17255 17257.
    • (1997) J Biol Chem , vol.272 , pp. 17255-17257
    • Hu, S.1    Vincenz, C.2    Ni, J.3    Gentz, R.4    Dixit, V.M.5
  • 27
    • 0030746740 scopus 로고    scopus 로고
    • Casper is a FADD- and caspase-related inducer of apoptosis
    • Shu HB, Halpin DR, Goeddel DV. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity 1997 6 : 751 763.
    • (1997) Immunity , vol.6 , pp. 751-763
    • Shu, H.B.1    Halpin, D.R.2    Goeddel, D.V.3
  • 28
    • 0030758315 scopus 로고    scopus 로고
    • MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death
    • Han DK, Chaudhary PM, Wright ME et al. MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc Natl Acad Sci U S A 1997 94 : 11333 11338.
    • (1997) Proc Natl Acad Sci U S a , vol.94 , pp. 11333-11338
    • Han, D.K.1    Chaudhary, P.M.2    Wright, M.E.3
  • 29
    • 0030961084 scopus 로고    scopus 로고
    • CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis
    • Inohara N, Koseki T, Hu Y, Chen S, Núñez G. CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis. Proc Natl Acad Sci U S A 1997 94 : 10717 10722.
    • (1997) Proc Natl Acad Sci U S a , vol.94 , pp. 10717-10722
    • Inohara, N.1    Koseki, T.2    Hu, Y.3    Chen, S.4    Núñez, G.5
  • 30
    • 7344220967 scopus 로고    scopus 로고
    • Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
    • Rasper DM, Vaillancourt JP, Hadano S et al. Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex. Cell Death Differ 1998 5 : 271 288.
    • (1998) Cell Death Differ , vol.5 , pp. 271-288
    • Rasper, D.M.1    Vaillancourt, J.P.2    Hadano, S.3
  • 31
    • 0030970013 scopus 로고    scopus 로고
    • Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
    • Thome M, Schneider P, Hofmann K. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 1997 386 : 517 521.
    • (1997) Nature , vol.386 , pp. 517-521
    • Thome, M.1    Schneider, P.2    Hofmann, K.3
  • 32
    • 0030950228 scopus 로고    scopus 로고
    • A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis
    • Hu S, Vincenz C, Buller M, Dixit VM. A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis. J Biol Chem 1997 272 : 9621 9624.
    • (1997) J Biol Chem , vol.272 , pp. 9621-9624
    • Hu, S.1    Vincenz, C.2    Buller, M.3    Dixit, V.M.4
  • 33
    • 0035192884 scopus 로고    scopus 로고
    • FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis
    • Krueger A, Baumann S, Krammer PH, Kirchhoff S. FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis. Mol Cell Biol 2001 21 : 8247 8254.
    • (2001) Mol Cell Biol , vol.21 , pp. 8247-8254
    • Krueger, A.1    Baumann, S.2    Krammer, P.H.3    Kirchhoff, S.4
  • 34
    • 0035496099 scopus 로고    scopus 로고
    • Regulation of lymphocyte proliferation and death by FLIP
    • Thome M, Tschopp J. Regulation of lymphocyte proliferation and death by FLIP. Nat Rev Immunol 2001 1 : 50 58.
    • (2001) Nat Rev Immunol , vol.1 , pp. 50-58
    • Thome, M.1    Tschopp, J.2
  • 35
    • 0033556310 scopus 로고    scopus 로고
    • The role of c-FLIP in modulation of CD95-induced apoptosis
    • Scaffidi C, Schmitz I, Krammer PH, Peter ME. The role of c-FLIP in modulation of CD95-induced apoptosis. J Biol Chem 1999 274 : 1541 1548.
    • (1999) J Biol Chem , vol.274 , pp. 1541-1548
    • Scaffidi, C.1    Schmitz, I.2    Krammer, P.H.3    Peter, M.E.4
  • 36
    • 0030746740 scopus 로고    scopus 로고
    • Casper is a FADD- and caspase-related inducer of apoptosis
    • Shu HB, Halpin DR, Goeddel DV. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity 1997 6 : 751 763.
    • (1997) Immunity , vol.6 , pp. 751-763
    • Shu, H.B.1    Halpin, D.R.2    Goeddel, D.V.3
  • 37
    • 0035827569 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex
    • Krueger A, Schmitz I, Baumann S, Krammer PH, Kirchhoff S. Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex. J Biol Chem 2001 276 : 20633 20640.
    • (2001) J Biol Chem , vol.276 , pp. 20633-20640
    • Krueger, A.1    Schmitz, I.2    Baumann, S.3    Krammer, P.H.4    Kirchhoff, S.5
  • 38
    • 0037160117 scopus 로고    scopus 로고
    • The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
    • Micheau O, Thome M, Schneider P et al. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem 2002 277 : 45162 45171.
    • (2002) J Biol Chem , vol.277 , pp. 45162-45171
    • Micheau, O.1    Thome, M.2    Schneider, P.3
  • 39
    • 0037099678 scopus 로고    scopus 로고
    • C-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
    • Chang DW, Xing Z, Pan Y et al. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J 2002 21 : 3704 3714.
    • (2002) EMBO J , vol.21 , pp. 3704-3714
    • Chang, D.W.1    Xing, Z.2    Pan, Y.3
  • 41
    • 0042466637 scopus 로고    scopus 로고
    • Interdimer processing mechanism of procaspase-8 activation
    • Chang DW, Xing Z, Capacio VL, Peter ME, Yang X. Interdimer processing mechanism of procaspase-8 activation. EMBO J 2003 22 : 4132 4142.
    • (2003) EMBO J , vol.22 , pp. 4132-4142
    • Chang, D.W.1    Xing, Z.2    Capacio, V.L.3    Peter, M.E.4    Yang, X.5
  • 42
    • 0028117561 scopus 로고
    • Effects of transfected complement regulatory proteins, MCP, DAF, and MCP/DAE hybrid, on complement-mediated swine endothelial cell lysis
    • Miyagawa S, Shirakura R, Iwata K et al. Effects of transfected complement regulatory proteins, MCP, DAF, and MCP/DAE hybrid, on complement-mediated swine endothelial cell lysis. Transplantation 1994 58 : 834 840.
    • (1994) Transplantation , vol.58 , pp. 834-840
    • Miyagawa, S.1    Shirakura, R.2    Iwata, K.3
  • 43
    • 16644389162 scopus 로고    scopus 로고
    • Porcine (Sus scrofa) cellular FLICE-like inhibitory protein (c-FLIP): Molecular cloning and comparison with the human and murine c-FLIP
    • Goto Y, Matsuda-Minehata F, Inoue N, Matsui T, Maeda A, Manabe N. Porcine (Sus scrofa) cellular FLICE-like inhibitory protein (c-FLIP): Molecular cloning and comparison with the human and murine c-FLIP. J Reprod Dev 2004 50 : 549 555.
    • (2004) J Reprod Dev , vol.50 , pp. 549-555
    • Goto, Y.1    Matsuda-Minehata, F.2    Inoue, N.3    Matsui, T.4    Maeda, A.5    Manabe, N.6
  • 44
    • 23244468079 scopus 로고    scopus 로고
    • Changes in expression of anti-apoptotic protein, c-FLIP, in granulosa cells during follicular atresia in porcine ovaries
    • Matsuda-Minehata F, Goto Y, Inoue N, Manabe N. Changes in expression of anti-apoptotic protein, c-FLIP, in granulosa cells during follicular atresia in porcine ovaries. Mol Reprod Dev 2005 72 : 145 151.
    • (2005) Mol Reprod Dev , vol.72 , pp. 145-151
    • Matsuda-Minehata, F.1    Goto, Y.2    Inoue, N.3    Manabe, N.4
  • 45
    • 0035034212 scopus 로고    scopus 로고
    • The immunological barrier to xenotransplantation
    • Cascalho M, Platt JL. The immunological barrier to xenotransplantation. Immunity 2001 14 : 437 446.
    • (2001) Immunity , vol.14 , pp. 437-446
    • Cascalho, M.1    Platt, J.L.2
  • 46
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer PH. CD95's deadly mission in the immune system. Nature 2000 407 : 789 795.
    • (2000) Nature , vol.407 , pp. 789-795
    • Krammer, P.H.1
  • 48
    • 0035870568 scopus 로고    scopus 로고
    • Early assessment of apoptosis in isolated islets of Langerhans
    • Cattan P, Berney T, Schena S et al. Early assessment of apoptosis in isolated islets of Langerhans. Transplantation. 2001 71 : 857 862.
    • (2001) Transplantation. , vol.71 , pp. 857-862
    • Cattan, P.1    Berney, T.2    Schena, S.3
  • 49
    • 0034456628 scopus 로고    scopus 로고
    • Cytokines induce both necrosis and apoptosis via a common Bcl-2-inhibitable pathway in rat insulin-producing cells
    • Saldeen J. Cytokines induce both necrosis and apoptosis via a common Bcl-2-inhibitable pathway in rat insulin-producing cells. Endocrinology 2000 141 : 2003 2010.
    • (2000) Endocrinology , vol.141 , pp. 2003-2010
    • Saldeen, J.1
  • 50
    • 33750846939 scopus 로고    scopus 로고
    • Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets
    • Maedler K, Schumann DM, Sauter N et al. Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets. Diabetes 2006 55 : 2713 2722.
    • (2006) Diabetes , vol.55 , pp. 2713-2722
    • Maedler, K.1    Schumann, D.M.2    Sauter, N.3
  • 51
    • 33847250987 scopus 로고    scopus 로고
    • The Fas pathway is involved in pancreatic beta cell secretory function
    • Schumann DM, Maedler K, Franklin I et al. The Fas pathway is involved in pancreatic beta cell secretory function. Proc Natl Acad Sci U S A 2007 104 : 2861 2866.
    • (2007) Proc Natl Acad Sci U S a , vol.104 , pp. 2861-2866
    • Schumann, D.M.1    Maedler, K.2    Franklin, I.3


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