Synthesis and characterization of polymethacrylamide having gabapentin moieties

Iranian Polymer Journal (English Edition)

Volumn 16, Issue 11, 2007, Pages 769-774

  Akat, Hakan ^a   Balcan, Mehmet ^a  

^a EGE UNIVERSITY   (Turkey)

Author keywords

Differential scanning calorimeter; Gabapentin; Polymethacrylamide; Radical polymerization; Thermogravimetric analysis

Indexed keywords

DIFFERENTIAL SCANNING CALORIMETRY; FREE RADICAL POLYMERIZATION; GLASS TRANSITION; PYROLYSIS; THERMOGRAVIMETRIC ANALYSIS;

GABAPENTIN; POLYMETHACRYLAMIDE; TRIETHYLAMINES;

POLYMERS;

EID: 38149051445     PISSN: 10261265     EISSN: 10261265     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Reddy G.J., ReddyA V.R., Naldu S.V., Synthesis and characterization of phenyl methacrylamide copolymers, Adv. Polym. Technol., 25, 41-50, 2006.
2. Sumerlin B.S., Donovan M.S., Mitsukami Y., Lowe A.B., McCormick C.L., Water-soluble polymers. 84. Controlled polymerization in aqueous media of anionic acrylamido monomers via RAFT, Macromolecules, 34, 6561-6564, 2001.
3. Donovan M.S., Sumerlin B.S., Lowe A.B., McCormick C.L., Controlled/"living" polymerization of sulfobetaine monomers directly in aqueous media via RAFT, Macromolecules, 35, 8663-8666, 2002.
4. D'Agosto F., Hughes R., Charreyre M.-T., Pichot C., Gilbert R.G., Molecular weight and functional end group control by RAFT polymerization of a bisubstituted acrylamide derivative, Macromolecules, 36, 621-629, 2003.
5. Xue W., Hamley I.W., Thermoreversible swelling behaviour of hydrogels based on N-isopropylacrylamide with a hydrophobic comonomer, Polymer, 43, 3069-3077, 2002.
6. Walker M.C., Patsalos P N., Clinical pharmacokinetics of new antiepileptic drugs, Pharm. Thera., 67, 351-384, 1995.
7. Gram L., Pharmacokinetics of new antiepileptic drugs, Epilepsia, 37, 12-16, 1996.
8. Gareri P., Gravina T., Ferreri G., Sarro G.D., Treatment of epilepsy in the elderly, Prog. Neurobiol., 58, 389-407, 1999.
9. 2+ influx and synaptic transmission in rat hippocampus and neocortex, Eur. J. Pharm., 449, 221-228, 2002;
10. Nori A., Kopeček J., Intracellular targeting of polymer-bound drugs for cancer chemotherapy, Adv. Drug Delivery Rev., 57, 609-636, 2005.
11. Akat H., Yildirim Y., Lambrecht E.Y., Yilmaz O., Balean M., Duman Y., Biological distribution of iodo-allyl gabapentin and iodo-gabapentin, J. Radioanal. Nuclear Chem., 275, 2008, in press.
12. Akat H., Balean M., Synthesis and radical polymerizations of acrylamides having Gabapentin moieties, e-Polymers, 94, 1-8, 2007.
13. Hoffman A.S., Polymers in Drug Delivery: Selecting the Right Polymer for Biomaterial Applications, CRC, Ch. 2, 2006.
14. Raillard Stephen P., Zhou Cindy X., Yao F., Manthati Suresh K., Xiang J., Gallop Mark A., Methods for synthesis of acyloxyalkyl derivatives of GABA analogs, US Patent 2004014940, 2004.
15. Kudo H., Sanda F., Endo T., Synthesis and radical polyaddition of optically active monomers derived from cysteine, Macromolecules, 32, 8370-8375, 1999.