메뉴 건너뛰기




Volumn 213, Issue 1, 2008, Pages 39-50

Developmental shift in TcR-mediated rescue of thymocytes from glucocorticoid-induced apoptosis

Author keywords

Apoptosis; Bcl 2; Double positive (DP) thymocytes; Glucocorticoid hormone (GC); Glucocorticoid receptor (GR); Mutual antagonism

Indexed keywords

CD3 ANTIBODY; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; LIPOCORTIN 5; PROTEIN BCL 2; T LYMPHOCYTE RECEPTOR;

EID: 38149042709     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2007.06.004     Document Type: Article
Times cited : (17)

References (51)
  • 1
    • 0037306522 scopus 로고    scopus 로고
    • The Ras/MAPK cascade and the control of positive selection
    • Alberolanti-Ila J., and Hernandez-Hoyos G. The Ras/MAPK cascade and the control of positive selection. Immunol. Rev. 191 (2003) 79-96
    • (2003) Immunol. Rev. , vol.191 , pp. 79-96
    • Alberolanti-Ila, J.1    Hernandez-Hoyos, G.2
  • 2
    • 3042778115 scopus 로고    scopus 로고
    • On the link between Bcl-2 family proteins and glucocorticoid-induced apoptosis
    • Almawi W.Y., Melemedjian O.K., and Jaoude M.M. On the link between Bcl-2 family proteins and glucocorticoid-induced apoptosis. J. Leukoc. Biol. 76 (2004) 7-14
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 7-14
    • Almawi, W.Y.1    Melemedjian, O.K.2    Jaoude, M.M.3
  • 3
    • 0035496231 scopus 로고    scopus 로고
    • Lymphostromal interactions in thymic development and function
    • Anderson G., and Jenkinson E.J. Lymphostromal interactions in thymic development and function. Nat. Rev. Immunol. 1 (2001) 31-40
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 31-40
    • Anderson, G.1    Jenkinson, E.J.2
  • 6
    • 0345516015 scopus 로고    scopus 로고
    • Production and flow cytometric application of a monoclonal anti-glucocorticoid receptor antibody
    • Berki T., Kumanovics G., Kumanovics A., Falus A., Ujhelyi E., and Nemeth P. Production and flow cytometric application of a monoclonal anti-glucocorticoid receptor antibody. J. Immunol. Methods 214 (1998) 19-27
    • (1998) J. Immunol. Methods , vol.214 , pp. 19-27
    • Berki, T.1    Kumanovics, G.2    Kumanovics, A.3    Falus, A.4    Ujhelyi, E.5    Nemeth, P.6
  • 7
    • 0036097603 scopus 로고    scopus 로고
    • Glucocorticoid (GC) sensitivity and GC receptor expression differ in thymocyte subpopulations
    • Berki T., Pálinkás L., Boldizsár F., and Németh P. Glucocorticoid (GC) sensitivity and GC receptor expression differ in thymocyte subpopulations. Int. Immun. 14 (2002) 463-469
    • (2002) Int. Immun. , vol.14 , pp. 463-469
    • Berki, T.1    Pálinkás, L.2    Boldizsár, F.3    Németh, P.4
  • 8
    • 0014872433 scopus 로고
    • Characteristics of the immunocompetent cells in the mouse thymus: cell population changes during cortisone-induced atrophy and subsequent regeneration
    • Blomgren H., and Andersson E. Characteristics of the immunocompetent cells in the mouse thymus: cell population changes during cortisone-induced atrophy and subsequent regeneration. Cell. Immunol. 1 (1970) 545-560
    • (1970) Cell. Immunol. , vol.1 , pp. 545-560
    • Blomgren, H.1    Andersson, E.2
  • 9
    • 0347626197 scopus 로고    scopus 로고
    • Antigen and glucocorticoid hormone (GC) induce positive selection of DP thymocytes in a TcR transgenic mouse model
    • Boldizsar F., Palinkas L., Bartis D., Nemeth P., and Berki T. Antigen and glucocorticoid hormone (GC) induce positive selection of DP thymocytes in a TcR transgenic mouse model. Immunol. Lett. 90 (2003) 97-102
    • (2003) Immunol. Lett. , vol.90 , pp. 97-102
    • Boldizsar, F.1    Palinkas, L.2    Bartis, D.3    Nemeth, P.4    Berki, T.5
  • 10
    • 33750937390 scopus 로고    scopus 로고
    • Low glucocorticoid receptor (GR), high Dig2 and low Bcl-2 expression in double positive thymocytes of Balb/c mice indicates their endogenous glucocorticoid hormone exposure
    • Boldizsár F., Pálinkás L., Czömpöly T., Bartis D., Németh P., and Berki T. Low glucocorticoid receptor (GR), high Dig2 and low Bcl-2 expression in double positive thymocytes of Balb/c mice indicates their endogenous glucocorticoid hormone exposure. Immunobiology 211 (2006) 785-796
    • (2006) Immunobiology , vol.211 , pp. 785-796
    • Boldizsár, F.1    Pálinkás, L.2    Czömpöly, T.3    Bartis, D.4    Németh, P.5    Berki, T.6
  • 11
    • 0036224429 scopus 로고    scopus 로고
    • Rapid glucocorticoid effects on immune cells
    • Buttgereit F., and Scheffold A. Rapid glucocorticoid effects on immune cells. Steroids 67 (2002) 529-534
    • (2002) Steroids , vol.67 , pp. 529-534
    • Buttgereit, F.1    Scheffold, A.2
  • 12
    • 0031918223 scopus 로고    scopus 로고
    • BCL-2 family: regulators of cell death
    • Chao D.T., and Korsmeyer S.J. BCL-2 family: regulators of cell death. Annu. Rev. Immunol. 16 (1998) 395-416
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 395-416
    • Chao, D.T.1    Korsmeyer, S.J.2
  • 13
    • 0027015928 scopus 로고
    • Glucocorticoid-induced apoptosis in the thymus
    • Cohen J.J. Glucocorticoid-induced apoptosis in the thymus. Semin. Immunol. 4 (1992) 363-369
    • (1992) Semin. Immunol. , vol.4 , pp. 363-369
    • Cohen, J.J.1
  • 14
    • 0028052385 scopus 로고
    • Flow-cytometric analysis of apoptotic and nonapoptotic T-cell receptor-transgenic thymocytes following in vitro presentation of antigen
    • Curnow S.J., Barad M., Brun-Roubereau N., and Schmitt-Verhulst A.M. Flow-cytometric analysis of apoptotic and nonapoptotic T-cell receptor-transgenic thymocytes following in vitro presentation of antigen. Cytometry 16 (1994) 41-48
    • (1994) Cytometry , vol.16 , pp. 41-48
    • Curnow, S.J.1    Barad, M.2    Brun-Roubereau, N.3    Schmitt-Verhulst, A.M.4
  • 15
    • 8344271002 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: updates
    • Frankfurt O., and Rosen S.T. Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: updates. Curr. Opin. Oncol. 16 (2004) 553-563
    • (2004) Curr. Opin. Oncol. , vol.16 , pp. 553-563
    • Frankfurt, O.1    Rosen, S.T.2
  • 16
    • 0034509630 scopus 로고    scopus 로고
    • Stress-free T-cell development: glucocorticoids are not obligatory
    • Godfrey D.I., Purton J.F., Boyd R.L., and Cole T.J. Stress-free T-cell development: glucocorticoids are not obligatory. Immunol. Today 21 (2000) 606-611
    • (2000) Immunol. Today , vol.21 , pp. 606-611
    • Godfrey, D.I.1    Purton, J.F.2    Boyd, R.L.3    Cole, T.J.4
  • 17
    • 7244232708 scopus 로고    scopus 로고
    • Cdk2 activation acts upstream of the mitochondrion during glucocorticoid induced thymocyte apoptosis
    • Granes F., Roig M.B., Brady H.J., and Gil-Gomez G. Cdk2 activation acts upstream of the mitochondrion during glucocorticoid induced thymocyte apoptosis. Eur. J. Immunol. 34 (2004) 2781-2790
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2781-2790
    • Granes, F.1    Roig, M.B.2    Brady, H.J.3    Gil-Gomez, G.4
  • 18
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross A., McDonnell J.M., and Korsmeyer S.J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 13 (1999) 1899-1911
    • (1999) Genes Dev , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 19
    • 0034641918 scopus 로고    scopus 로고
    • The biochemisty of apoptosis
    • Hengartner M.O. The biochemisty of apoptosis. Nature 407 (2000) 770-776
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 20
    • 27744477444 scopus 로고    scopus 로고
    • Mammalian initiator apoptotic caspases
    • Ho P.K., and Hawkins C.J. Mammalian initiator apoptotic caspases. FEBS J. 272 (2005) 5436-5453
    • (2005) FEBS J. , vol.272 , pp. 5436-5453
    • Ho, P.K.1    Hawkins, C.J.2
  • 21
    • 0025971637 scopus 로고
    • Rescue of thymocytes and T cell hybridomas from glucocorticoid-induced apoptosis by stimulation via the T cell receptor/CD3 complex: a possible in vitro model for positive selection of the T cell repertoire
    • Iwata M., Hanaoka S., and Sato K. Rescue of thymocytes and T cell hybridomas from glucocorticoid-induced apoptosis by stimulation via the T cell receptor/CD3 complex: a possible in vitro model for positive selection of the T cell repertoire. Eur. J. Immunol. 21 (1991) 643-648
    • (1991) Eur. J. Immunol. , vol.21 , pp. 643-648
    • Iwata, M.1    Hanaoka, S.2    Sato, K.3
  • 22
    • 0024444304 scopus 로고
    • Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor
    • Kaye J., Hsu M.L., Sauron M.E., Jameson S.C., Gascoigne N.R., and Hedrick S.M. Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature 341 (1989) 746-749
    • (1989) Nature , vol.341 , pp. 746-749
    • Kaye, J.1    Hsu, M.L.2    Sauron, M.E.3    Jameson, S.C.4    Gascoigne, N.R.5    Hedrick, S.M.6
  • 24
    • 0034055693 scopus 로고    scopus 로고
    • Self-antigen presentation by thymic stromal cells: a subtle division of labor
    • Klein L., and Kyewski B. Self-antigen presentation by thymic stromal cells: a subtle division of labor. Curr. Opin. Immunol. 12 (2000) 179-186
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 179-186
    • Klein, L.1    Kyewski, B.2
  • 25
    • 33645099763 scopus 로고    scopus 로고
    • Thymic microenvironments for T cell differentiation and selection
    • Ladi E., Yin X., Chtanova T., and Robey E.A. Thymic microenvironments for T cell differentiation and selection. Nat. Immunol. 7 (2006) 338-343
    • (2006) Nat. Immunol. , vol.7 , pp. 338-343
    • Ladi, E.1    Yin, X.2    Chtanova, T.3    Robey, E.A.4
  • 27
    • 0035124549 scopus 로고    scopus 로고
    • T cell receptor signaling
    • Lin J., and Weiss A. T cell receptor signaling. J. Cell Sci. 114 (2001) 243-244
    • (2001) J. Cell Sci. , vol.114 , pp. 243-244
    • Lin, J.1    Weiss, A.2
  • 28
    • 0028448483 scopus 로고
    • Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points
    • Linette G.P., Grusby M.J., Hedrick S.M., Hansen T.H., Glimcher L.H., and Korsmeyer S.J. Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. Immunity 1 (1994) 197-205
    • (1994) Immunity , vol.1 , pp. 197-205
    • Linette, G.P.1    Grusby, M.J.2    Hedrick, S.M.3    Hansen, T.H.4    Glimcher, L.H.5    Korsmeyer, S.J.6
  • 29
    • 0037879052 scopus 로고    scopus 로고
    • The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update
    • Ly J.D., Grubb D.R., and Lawen A. The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update. Apoptosis 8 (2003) 115-128
    • (2003) Apoptosis , vol.8 , pp. 115-128
    • Ly, J.D.1    Grubb, D.R.2    Lawen, A.3
  • 31
    • 0037438473 scopus 로고    scopus 로고
    • Dexamethasone-induced apoptosis of thymocytes: role of glucocorticoid receptor-associated Src kinase and caspase-8 activation
    • Marchetti M.C., Di Marco B., Cifone G., Migliorati G., and Riccardi C. Dexamethasone-induced apoptosis of thymocytes: role of glucocorticoid receptor-associated Src kinase and caspase-8 activation. Blood 101 (2003) 585-593
    • (2003) Blood , vol.101 , pp. 585-593
    • Marchetti, M.C.1    Di Marco, B.2    Cifone, G.3    Migliorati, G.4    Riccardi, C.5
  • 32
    • 0028790829 scopus 로고
    • Bcl-2 blocks glucocorticoid- but not Fas- or activation-induced apoptosis in T cell hybridoma
    • Memon S.A., Moreno M.B., Petrak D., and Zacharchuk C.M. Bcl-2 blocks glucocorticoid- but not Fas- or activation-induced apoptosis in T cell hybridoma. J. Immunol. 155 (1995) 4644-4652
    • (1995) J. Immunol. , vol.155 , pp. 4644-4652
    • Memon, S.A.1    Moreno, M.B.2    Petrak, D.3    Zacharchuk, C.M.4
  • 33
    • 5444224643 scopus 로고    scopus 로고
    • Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues
    • Pendergrass W., Wolf N., and Poot M. Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues. Cytometry A 61 (2004) 162-169
    • (2004) Cytometry A , vol.61 , pp. 162-169
    • Pendergrass, W.1    Wolf, N.2    Poot, M.3
  • 36
    • 0032964256 scopus 로고    scopus 로고
    • Developmental stages in the human thymus
    • Res P., and Spits H. Developmental stages in the human thymus. Semin. Immunol. 11 (1999) 39-46
    • (1999) Semin. Immunol. , vol.11 , pp. 39-46
    • Res, P.1    Spits, H.2
  • 38
    • 0037643416 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid action and resistance
    • Schaaf M.J., and Cidlowski J.A. Molecular mechanisms of glucocorticoid action and resistance. J. Steroid Biochem. Mol. Biol. 83 (2002) 37-48
    • (2002) J. Steroid Biochem. Mol. Biol. , vol.83 , pp. 37-48
    • Schaaf, M.J.1    Cidlowski, J.A.2
  • 39
    • 0033973837 scopus 로고    scopus 로고
    • The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation
    • Schnaider T., Somogyi J., Csermely P., and Szamel M. The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation. Cell Stress Chaperones 5 (2000) 52-61
    • (2000) Cell Stress Chaperones , vol.5 , pp. 52-61
    • Schnaider, T.1    Somogyi, J.2    Csermely, P.3    Szamel, M.4
  • 41
    • 31344468014 scopus 로고    scopus 로고
    • Role of mitochondrial glucocorticoid receptor in glucocorticoid-induced apoptosis
    • Sionov R.V., Cohen O., Kfir S., Zilberman Y., and Yefenof E. Role of mitochondrial glucocorticoid receptor in glucocorticoid-induced apoptosis. J. Exp. Med. 203 (2006) 189-201
    • (2006) J. Exp. Med. , vol.203 , pp. 189-201
    • Sionov, R.V.1    Cohen, O.2    Kfir, S.3    Zilberman, Y.4    Yefenof, E.5
  • 42
    • 0027447541 scopus 로고
    • Steroid receptors and their associated proteins
    • Smith D.F., and Toft D.O. Steroid receptors and their associated proteins. Mol. Endocrinol. 7 (1993) 4-11
    • (1993) Mol. Endocrinol. , vol.7 , pp. 4-11
    • Smith, D.F.1    Toft, D.O.2
  • 44
    • 0242417043 scopus 로고    scopus 로고
    • Mutually antagonistic signals regulate selection of the T cell repertoire
    • Stephens G.L., Ashwell J.D., and Ignatowicz L. Mutually antagonistic signals regulate selection of the T cell repertoire. Int. Immunol. 15 (2003) 623-632
    • (2003) Int. Immunol. , vol.15 , pp. 623-632
    • Stephens, G.L.1    Ashwell, J.D.2    Ignatowicz, L.3
  • 45
    • 0033179257 scopus 로고    scopus 로고
    • Thymus-derived glucocorticoids set the thresholds for thymocyte selection by inhibiting TCR-mediated thymocyte activation
    • Vacchio M.S., Lee J.Y., and Ashwell J.D. Thymus-derived glucocorticoids set the thresholds for thymocyte selection by inhibiting TCR-mediated thymocyte activation. J. Immunol. 163 (1999) 1327-1333
    • (1999) J. Immunol. , vol.163 , pp. 1327-1333
    • Vacchio, M.S.1    Lee, J.Y.2    Ashwell, J.D.3
  • 46
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis D.J., Sorenson C.M., Shutter J.R., and Korsmeyer S.J. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75 (1993) 229-240
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 47
    • 0029043888 scopus 로고
    • A novel assay for apoptosis flow cytometric detection of phosphatidylserine expression on early apoptotic cell using fluorescein labelled Annexin V
    • Vermes I., Haanen C., Steffens-Nakken H., and Reutelingsperger C. A novel assay for apoptosis flow cytometric detection of phosphatidylserine expression on early apoptotic cell using fluorescein labelled Annexin V. J. Immunol. Methods 184 (1995) 39-51
    • (1995) J. Immunol. Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 48
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • Wang X. The expanding role of mitochondria in apoptosis. Genes Dev. 15 (2001) 2922-2933
    • (2001) Genes Dev. , vol.15 , pp. 2922-2933
    • Wang, X.1
  • 50
    • 0025613973 scopus 로고
    • Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic
    • Zacharchuk C.M., Mercep M., Chakraborti P.K., Simons Jr. S.S., and Ashwell J.D. Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic. J. Immunol. 145 (1990) 4037-4045
    • (1990) J. Immunol. , vol.145 , pp. 4037-4045
    • Zacharchuk, C.M.1    Mercep, M.2    Chakraborti, P.K.3    Simons Jr., S.S.4    Ashwell, J.D.5
  • 51
    • 0034665305 scopus 로고    scopus 로고
    • Spontaneous thymocyte apoptosis is regulated by a mitochondrion mediated signaling pathway
    • Zhang J., Mikecz K., Finnegan A., and Glant T.T. Spontaneous thymocyte apoptosis is regulated by a mitochondrion mediated signaling pathway. J. Immunol. 165 (2000) 2970-2974
    • (2000) J. Immunol. , vol.165 , pp. 2970-2974
    • Zhang, J.1    Mikecz, K.2    Finnegan, A.3    Glant, T.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.