Water distribution and natural moisturizer factor content in human skin equivalents are regulated by environmental relative humidity

Journal of Investigative Dermatology

Volumn 128, Issue 2, 2008, Pages 378-388

  Bouwstra, Joke A ^a   Groenink, H Wouter W ^a   Kempenaar, Joop A ^a   Romeijn, Stefan G ^a   Ponec, Maria ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PYROGLUTAMIC ACID;

ARTICLE; CELL SWELLING; CONTROLLED STUDY; DESQUAMATION; ENVIRONMENTAL FACTOR; HUMAN; HUMAN CELL; HUMIDITY; HYDRATION; MOISTURE; PH MEASUREMENT; PRIORITY JOURNAL; SKIN FUNCTION; STRATUM CORNEUM; WATER SUPPLY;

EID: 38149040866     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700994     Document Type: Article

References (32)

1. Bouwstra JA, de Graaff AM, Gooris GS, Nijsse J, Wiechers JW, van Aelst AC (2003) Water distribution and related morphology in human stratum corneum at different hydration levels. J Invest Dermatol 120:750-8
2. Caspers PJ, Lucassen PW, Puppels GJ (2003) Combined in vivo confocal Raman spectroscopy and confocal microscopy of human skin. Biophys J 85:572-80
3. Choi EH, Man MQ, Wang F, Zhang X, Brown BE, Feingold KR et al. (2005) Is endogenous glycerol a determinant of stratum corneum hydration in humans? J Invest Dermatol 125:288-93
4. DeClerqc L, Muizzuddi N, Hellemans L, van Overloop L, Sparacio R, Marenus K et al. (2002) Adaptation response in human skin barrier to a hot & dry environment. J Invest Dermatol 119:716
5. El Ghalbzouri A, Lamme E, Ponec M (2002) Crucial role of fibroblasts in regulating epidermal morphogenesis. Cell Tissue Res 310:189-99
6. Fluhr JW, Qiang MM, Brown BE, Wertz PW, Crumrine D, Sundberg JP et al. (2003) Glycerol regulates stratum corneum hydration in sebaceous gland deficient (Asebia) mice. J Invest Dermatol 120:728-37
7. Furuse M, Hata M, Furuse K, Yoshida Y, Haratake A, Sugitani Y et al. (2002) Claudine based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cel Biol 156:1099-111
8. Hara M, Verkman AS (2003) Glycerol replacement corrects defective skin hydration, elasticity and barrier function in aquaporin-3-deficient mice. PNAS 100:7360-5
9. Harding CR, Scott IR (1983) Histidine-rich proteins (filaggrins). Structural and functional heterogeneity during epidermal differentiation. J Mol Biol 170:651-73
10. Harding CR, Watkinson A, Rawlings AV (2000) Dry skin moisturisation and corneodesmolysis. Int J Cosm Sci 22:21-52
11. Horikoshi T, Igarashi S, Uchiwa H, Brysk H, Brysk MM (1999) Role of endogenous cathepsin D-like and chemotrypsin-like proteolysis in human epidermal dequamation. Br J Dermatol 141:453-9
12. Horikoshi T, Matsumoto M, Usuki A, Igarashi S, Hikima R, Huchiwa H et al. (2005) Effects of glycolic acid on desquamation-regulating proteinases in human stratum corneum. Exp Dermatol 14:34-40
13. Igarashi S, Takizawa T, Yasuda Y, Uchiwa H, Hayashi S, Brysk H et al. (2004) Cathepsin D, but not cathepsin E, degrades desmosomes during epidermal dequamation. Br J Dermatol 151:355-61
14. Lundstrom A, Serre G, Haftek M, Egelrud T (1990) Evidence for a role of corneodesmosin, a protein which may serve to modify desmosomes during cornification in stratum corneum cell cohesion and desquamations. Arch Dermatol Res 282:237-43
15. Nakagawa N, Sakai S, Matsumoto M, Yamada K, Nagano M, Yuki T et al. (2004) Relationship between NMF (lactate and potassium) content and the physical properties of the stratum corneum in healthy subjects. J Invest Dermatol 122:755-63
16. Pierard GE, Goffin V, Le-Hermanns T, Pierard-Franchimont C (2000) Corneocyte desquamation. Int J Mol Med 6:217-21
17. Ponec M (2002) Skin constructs for replacement of skin tissues for in vitro testing. Adv Drug Deliv Rev 54(Suppl 1):S19-30
18. Ponec M, Boelsma E, Weerheim AM (2000) Covalently bound lipids in reconstructed human epithelia. Acta Derm Venereol 80:89-93
19. Ponec M, Gibbs S, Pilgram G, Boelsma E, Koerten H, Bouwstra J et al. (2001) Barrier function in reconstructed epidermis and its resemblance to native human skin. Skin Pharmacol Appl Skin Physiol 14(Suppl 1):63-71
20. Ponec M, Kempenaar J, Weerheim AM (2002) The lack of desquamation, the Achilles heel of reconstructed epidermis. Int J Cosm Sci 24:263-72
21. Ponec M, Weerheim A, Lankhorst P, Wertz P (2003) New acylceramide in native and reconstructed epidermis. J Invest Dermatol 120:581-8
22. Rawlings AV (2003) Trends in stratum corneum research. Intern J Cosm Sci 25:1-33
23. Rawlings AV, Harding CR (2004) Moisturization and skin barrier function. Dermatol Ther 17:43-8
24. Rawlings AV, Scott IR, Harding CR, Bowser PA (1994) Stratum corneum moisturization at the molecular level. J Invest Dermatol 103:731-41
25. Rawlings AV, Matts PJ (2005) Stratum corneum moisturization at the molecular level: an update in relation to dry skin cycle. J Invest Dermatol 124:1099-110
26. Simon M, Bernard D, Minondo A-M, Camus C, Fiat F, Corcuff P et al. (2001) Persistence of both peripheral and non-peripheral corneodesmosomes in the upper stratum corneum of winter xerosis skin versus only peripheral in normal skin. J Invest Dermatol 116:23-30
27. Smola H, Thiekotter G, Fugenic NNE (1998) Mutual induced grow factor gene expression by epidermal-dermal cell interaction. J Cell Biol 122:417-29
28. Suzuki Y, Nomura Y, Koyama J, Horii I (1994) The role of proteases in stratum corneum: involvement in stratum corneum desquamation. Arch Dermatol Res 286:369-75
29. Swartzendruber DC, Wertz PW, Madison KC, Downing DT (1987) Evidence that the corneocyte has a cemically bound lipid envelope. J Invest Dermatol 88:709-13
30. Vicanova J, Boelsma E, Mommaas AM, Kempenaar JA, Forslind B, Pallon J et al. (1998) Normalization of epidermal calcium distribution profile in reconstructed human epidermis is related to improvement of terminal differentiation and stratum corneum barrier formation. J Invest Dermatol 111:97-106
31. Watkinson A, Harding C, Moore A, Coan P (2001) Water modulation of stratum corneum chymotryptic enzyme activity and desquamation. Arch Dermatol Res 293:470-6
32. Wertz PW, Madison KC, Downing DT (1989) Covalently bound lipids of human stratum corneum. J Invest Dermatol 92:109-11